Cotargeting of BTK and MALT1 overcomes resistance to BTK inhibitors in mantle cell lymphoma

Jiang, VC; Liu, Y; Lian, JW; Huang, SJ; Jordan, A; Cai, QS; Lin, RT; Yan, FF; McIntosh, J; Li, YJ; Che, YX; Chen, ZH; Vargas, J; Badillo, M; Bigcal, JN; Lee, HH; Wang, W; Yao, YX; Nie, L; Flowers, CR; Wang, MC

Wang, MC (通讯作者)，Univ Texas MD Anderson Canc Ctr, Dept Lymphoma & Myeloma, Houston, TX 77030 USA.

JOURNAL OF CLINICAL INVESTIGATION, 2023; 133 (3):

Abstract

Bruton's tyrosine kinase (BTK) is a proven target in mantle cell lymphoma (MCL), an aggressive subtype of non-Hodgkin lymphoma. However, resistance to......

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