Measuring the reproducibility and quality of Hi-C data

Yardimci, GG; Ozadam, H; Sauria, MEG; Ursu, O; Yan, KK; Yang, T; Chakraborty, A; Kaul, A; Lajoie, BR; Song, F; Zhan, Y; Ay, F; Gerstein, M; Kundaje, A; Li, QH; Taylor, J; Yue, F; Dekker, J; Noble, WS

Noble, WS (reprint author), Univ Washington, Dept Genome Sci, Seattle, WA 98195 USA.; Dekker, J (reprint author), Univ Massachusetts, Med Sch, Program Syst Biol, Worcester, MA 01605 USA.

GENOME BIOLOGY, 2019; 20 ():

Abstract

BackgroundHi-C is currently the most widely used assay to investigate the 3D organization of the genome and to study its role in gene regulation, DNA ......

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