Current status and progress in using radiolabelled PARP-1 inhibitors for imaging PARP-1 expression in tumours

Wang, QN; Zhang, JB

Zhang, JB (通讯作者)，Beijing Normal Univ, Key Lab Radiopharmaceut, NMPA Key Lab Res & Evaluat Radiopharmaceut, Coll Chem,Minist Educ,Natl Med Prod Adm, Beijing 100875, Peoples R China.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022; 242 ():

Abstract

Poly(ADP-ribose) polymerase-1 (PARP-1) is a key enzyme in the DNA repair process, and the overexpression of PARP-1 in several tumours makes this enzym......

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