Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments

Guix, FX; Sannerud, R; Berditchevski, F; Arranz, AM; Horre, K; Snellinx, A; Thathiah, A; Saido, T; Saito, T; Rajesh, S; Overduin, M; Kumar-Singh, S; Radaelli, E; Corthout, N; Colombelli, J; Tosi, S; Munck, S; Salas, IH; Annaert, W; De Strooper, B

Guix, FX; De Strooper, B (reprint author), VIB, VIB Ctr Brain & Dis Res, Leuven, Belgium.; Guix, FX; De Strooper, B (reprint author), Katholieke Univ Leuven, Ctr Human Genet, Leuven, Gasthuisberg O&, Belgium.; Guix, FX; De Strooper, B (reprint author), Ka

MOLECULAR NEURODEGENERATION, 2017; 12 ( ):

Abstract

Background: The mechanisms behind A beta-peptide accumulation in non- familial Alzheimer's disease (AD) remain elusive. Proteins of the tetraspanin fa......

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