Administration of 5-methoxyindole-2-carboxylic acid that potentially targets mitochondrial dihydrolipoamide dehydrogenase confers cerebral preconditioning against ischemic stroke injury

Wu, JZ; Li, RR; Li, WJ; Ren, M; Thangthaeng, N; Sumien, N; Liu, R; Yang, SH; Simpkins, JW; Forster, MJ; Yan, LJ

Yan, LJ (reprint author), Univ North Texas, Hlth Sci Ctr, UNT Syst Coll Pharm, Dept Pharmaceut Sci, 3500 Camp Bowie Blvd, Ft Worth, TX 76107 USA.

FREE RADICAL BIOLOGY AND MEDICINE, 2017; 113 ( ): 244

Abstract

The objective of this study was to investigate a possible role of mitochondrial dihydrolipoamide dehydrogenase (DLDH) as a chemical preconditioning ta......

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