Regulation of HLTF-mediated PCNA polyubiquitination by RFC and PCNA monoubiquitination levels determines choice of damage tolerance pathway

Masuda, Y; Mitsuyuki, S; Kanao, R; Hishiki, A; Hashimoto, H; Masutani, C

Masuda, Y (reprint author), Nagoya Univ, Res Inst Environm Med, Dept Genome Dynam, Chikusa Ku, Furo Cho, Nagoya, Aichi 4648601, Japan.; Masuda, Y (reprint author), Nagoya Univ, Grad Sch Med, Showa Ku, 65 Tsurumai Cho, Nagoya, Aichi 4668550, Japan.

NUCLEIC ACIDS RESEARCH, 2018; 46 (21): 11340

Abstract

DNA-damage tolerance protects cells via at least two sub-pathways regulated by proliferating cell nuclear antigen (PCNA) ubiquitination in eukaryotes:......

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