Lancet Oncol:低水平空气污染仍会增加肺癌风险

2013-07-29 Ole Raaschou-Nielsen 《柳叶刀肿瘤》

一项欧洲最新研究表明,即使空气污染处于较低水平,哪怕在欧盟标准之内,长期处于颗粒物空气污染环境也会增加人们罹患肺癌的风险。 瑞典卡罗林斯卡医学院在一份公报中称,该医学院和欧洲其他国家科研机构的研究人员对涉及欧洲9国31.3万人的追踪调查结果进行了分析,这些人在13年中有2095人患了肺癌。通过对调查对象生活环境的可吸入颗粒物PM2.5和PM10浓度进行估测发现,患肺癌风险与长期吸入空气中的可吸入

一项欧洲最新研究表明,即使空气污染处于较低水平,哪怕在欧盟标准之内,长期处于颗粒物空气污染环境也会增加人们罹患肺癌的风险。

瑞典卡罗林斯卡医学院在一份公报中称,该医学院和欧洲其他国家科研机构的研究人员对涉及欧洲9国31.3万人的追踪调查结果进行了分析,这些人在13年中有2095人患了肺癌。通过对调查对象生活环境的可吸入颗粒物PM2.5和PM10浓度进行估测发现,患肺癌风险与长期吸入空气中的可吸入颗粒物浓度成正比。在研究中,研究人员建立了数据模型,排除了吸烟、体重以及职业等因素对研究结果的影响。

分析表明,当每1立方米空气中的PM2.5每增加5微克时,患肺癌的风险会增加18%;当每1立方米空气中的PM10每增加10微克时,患肺癌、特别是肺腺癌的风险则会增加22%。即使可吸入颗粒物浓度低于欧盟标准时也是如此。欧盟规定的PM2.5和PM10最高限值分别为年均浓度每立方米25微克和40微克。

研究人员说,他们发现没有一个绝对无风险的安全值,“(可吸入颗粒物浓度)越高越差,越低越好”。

该项研究是“欧洲空气污染效应队列研究”项目的一部分。研究成果已发表在《柳叶刀肿瘤》杂志上。

Raaschou-Nielsen O, Andersen ZJ, Beelen R, Samoli E, Stafoggia M, Weinmayr G, Hoffmann B, Fischer P, Nieuwenhuijsen MJ, Brunekreef B, Xun WW, Katsouyanni K, Dimakopoulou K, Sommar J, Forsberg B, Modig L, Oudin A, Oftedal B, Schwarze PE, Nafstad P, De Faire U, Pedersen NL, Ostenson CG, Fratiglioni L, Penell J, Korek M, Pershagen G, Eriksen KT, Sørensen M, Tjønneland A, Ellermann T, Eeftens M, Peeters PH, Meliefste K, Wang M, Bueno-de-Mesquita B, Key TJ, de Hoogh K, Concin H, Nagel G, Vilier A, Grioni S, Krogh V, Tsai MY, Ricceri F, Sacerdote C, Galassi C, Migliore E, Ranzi A, Cesaroni G, Badaloni C, Forastiere F, Tamayo I, Amiano P, Dorronsoro M, Trichopoulou A, Bamia C, Vineis P, Hoek G.Air pollution and lung cancer incidence in 17 European cohorts: prospective analyses from the European Study of Cohorts for Air Pollution Effects (ESCAPE).Lancet Oncol. 2013 Jul 10. doi:pii: S1470-2045(13)70279-1. 10.1016/S1470-2045(13)70279-1. [Epub ahead of print]PMID:23849838

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    2013-08-20 howi
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    2014-03-28 minlingfeng
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    2014-03-20 sjq027
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