Vasc Health Risk Manag:牙周炎可能是卒中的一个危险因素,尤其是缺血性卒中

2020-09-27 MedSci原创 MedSci原创

本系统性回顾和荟萃分析调查了牙周炎与卒中之间的关系,研究结果已在线发表于asc Health Risk Manag。

本系统性回顾和荟萃分析调查了牙周炎与卒中之间的关系,研究结果已在线发表于Vasc Health Risk Manag。

该综述遵循系统性综述和荟萃分析首选报告项目(PRISMA)指南建立的方法。在5个数据库和2个灰色文献源中进行检索。在对文章进行筛选后,进行了偏倚风险评估。进行了三项荟萃分析。评估病例对照研究中卒中和牙周炎之间的总体关联;病例对照研究中缺血性卒中和牙周炎;队列研究中卒中和牙周炎之间的关联。使用I2指数评估异质性,同时计算赔率比(P<0.05)。应用推荐评估、发展和评价分级(GRADE)来评估证据水平。

 

研究人员共筛选出2193项潜在的相关研究,其中10项研究纳入定性和定量分析。所有的文章都被认为是低风险的偏见和低水平的确定性。结果显示,在队列研究中,这两种疾病与卒中风险增加呈正相关(RR 1.88[1.55,2.29],P<0.00001,I2=0%),在病例对照研究中,这两种疾病与缺血性卒中事件呈正相关(RR 2.72[2.00,3.71],P<0.00001,I2=4%)。

综上所述,该结果表明,牙周炎可能是卒中的一个危险因素,尤其是在缺血性卒中。然而,为了得出可靠的结论,有必要进行设计优良的新研究。

 

原始出处:

 

Nathalia Carolina Fernandes FagundesAnna Paula Costa Ponte Sousa Carvalho Almeida, et al., Periodontitis As A Risk Factor For Stroke: A Systematic Review And Meta-Analysis. Vasc Health Risk Manag. 2019 Nov 6;15:519-532. doi: 10.2147/VHRM.S204097.

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    2021-03-17 quxin068
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time=2020-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026696, encodeId=0c791026696be, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sun Sep 27 16:48:28 CST 2020, time=2020-09-27, status=1, ipAttribution=)]
    2020-10-08 AspirantSuo
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time=2020-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026696, encodeId=0c791026696be, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sun Sep 27 16:48:28 CST 2020, time=2020-09-27, status=1, ipAttribution=)]
    2020-12-15 1dedaedcm53(暂无匿称)

    现在突然很多因素都与卒中有关

    0

  5. 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time=2020-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026696, encodeId=0c791026696be, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sun Sep 27 16:48:28 CST 2020, time=2020-09-27, status=1, ipAttribution=)]
    2020-12-07 shizhenshan
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level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Tue Sep 29 04:48:28 CST 2020, time=2020-09-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=888767, encodeId=0f74888e67b0, content=中国人对口腔卫生和健康的意识普遍不足,需要多一些这方面的学习文章<a href='/topic/show?id=16e8382e7cd' target=_blank style='color:#2F92EE;'>#口腔健康#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38277, encryptionId=16e8382e7cd, topicName=口腔健康)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210607/9f00a0de660e4b36b77a9a5f7620d6bf/98c22b17ddf7446fa7b9a618fabcb9f7.jpg, createdBy=a8fb2299762, createdName=Psycho.Dr Du, createdTime=Sun Sep 27 17:31:21 CST 2020, time=2020-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026696, encodeId=0c791026696be, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sun Sep 27 16:48:28 CST 2020, time=2020-09-27, status=1, ipAttribution=)]
  8. 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time=2020-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026696, encodeId=0c791026696be, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sun Sep 27 16:48:28 CST 2020, time=2020-09-27, status=1, ipAttribution=)]
  9. [GetPortalCommentsPageByObjectIdResponse(id=1939109, encodeId=a55a1939109ca, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Wed Mar 17 10:48:28 CST 2021, time=2021-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1893326, encodeId=234d1893326bc, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, 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level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Tue Sep 29 04:48:28 CST 2020, time=2020-09-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=888767, encodeId=0f74888e67b0, content=中国人对口腔卫生和健康的意识普遍不足,需要多一些这方面的学习文章<a href='/topic/show?id=16e8382e7cd' target=_blank style='color:#2F92EE;'>#口腔健康#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38277, encryptionId=16e8382e7cd, topicName=口腔健康)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210607/9f00a0de660e4b36b77a9a5f7620d6bf/98c22b17ddf7446fa7b9a618fabcb9f7.jpg, createdBy=a8fb2299762, createdName=Psycho.Dr Du, createdTime=Sun Sep 27 17:31:21 CST 2020, time=2020-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026696, encodeId=0c791026696be, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sun Sep 27 16:48:28 CST 2020, time=2020-09-27, status=1, ipAttribution=)]
    2020-09-27 Psycho.Dr Du

    中国人对口腔卫生和健康的意识普遍不足,需要多一些这方面的学习文章#口腔健康#

    0

  10. 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level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Tue Sep 29 04:48:28 CST 2020, time=2020-09-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=888767, encodeId=0f74888e67b0, content=中国人对口腔卫生和健康的意识普遍不足,需要多一些这方面的学习文章<a href='/topic/show?id=16e8382e7cd' target=_blank style='color:#2F92EE;'>#口腔健康#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38277, encryptionId=16e8382e7cd, topicName=口腔健康)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210607/9f00a0de660e4b36b77a9a5f7620d6bf/98c22b17ddf7446fa7b9a618fabcb9f7.jpg, createdBy=a8fb2299762, createdName=Psycho.Dr Du, createdTime=Sun Sep 27 17:31:21 CST 2020, time=2020-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026696, encodeId=0c791026696be, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sun Sep 27 16:48:28 CST 2020, time=2020-09-27, status=1, ipAttribution=)]
    2020-09-27 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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J Cereb Blood Flow Metab:卒中诱导的免疫抑制和吞咽困难与卒中相关肺炎独立相关

脑卒中相关肺炎是脑卒中后常见的并发症,与不良结局有关。吞咽困难是脑卒中相关肺炎的已知危险因素,但现有的证据表明,脑卒中诱导的免疫抑制状态增加了脑卒中相关肺炎的易感性。本研究旨在通过研究单细胞HLA-D

类似于急性冠脉综合征及中风,你会想起该病吗?

嗜酸性肉芽肿性多血管炎,也称为Churg-Strauss综合征(churg-strauss syndrome,CSS),以哮喘、嗜酸性粒细胞增多及血管炎为临床表现的、累及多器官的罕见疾病。

Neurology:服用达比加群卒中患者的溶栓治疗

达比加群酯(达比加群)是一种直接凝血酶抑制剂,已被证明可预防心房颤动患者的卒中。伊达鲁珠单抗(Idarucizumab)是一种人源化单克隆抗体片段,旨在逆转达比加群的抗凝作用。伊达鲁珠单抗与达比加群的

王拥军:中国卒中报告2019发布

Stroke & Vascular Neurology