Gynecol Endocrinol:连续三次重复试管婴儿患者体外受精周期中顺序胚胎移植与囊胚移植的妊娠结局

2020-07-25 MedSci原创 MedSci原创

本研究旨在确定在体外受精-胚胎移植(IVF/ET)中,连续3次反复IVF失败的患者在第3天和第5天都进行双胚移植与第5天单独移植的妊娠率。

本研究旨在确定在体外受精-胚胎移植(IVF/ET)中,连续3次反复IVF失败的患者在第3天和第5天都进行双胚移植与第5天单独移植的妊娠率。

 

在这项对照试验中,将连续3次反复IVF失败的预定IVF/ET的女性随机分为取卵后第2天和第5天依次移植胚胎(第1组,n=60)或第5天进行囊胚ET(第2组,n=60)作为对照组。主要结果测量是化学和临床妊娠率。两组的基线和周期特征具有可比性。与ET组第5天(38.3%)相比,序贯ET组的化学和临床妊娠率(40%)相似(P值=.85)。由此看来,对于3次反复IVF-ET失败的患者,双ET与第5天的囊胚ET相比,并不会增加妊娠的几率。

 

原始出处:

 

Ensieh Shahrokh TehraninejadElham Raisi, et al., The sequential embryo transfer compared to blastocyst embryo transfer in in vitro fertilization (IVF) cycle in patients with the three repeated consecutive IVF. A randomized controlled trial. Gynecol Endocrinol. 2019 Nov;35(11):955-959. doi: 10.1080/09513590.2019.1613639. 

 

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    2020-07-26 ailian1202
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1813183, encodeId=d67d181318368, content=<a href='/topic/show?id=1fdd91e56f7' target=_blank style='color:#2F92EE;'>#试管婴#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91756, encryptionId=1fdd91e56f7, topicName=试管婴)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11b4465, createdName=ying_wu, createdTime=Tue Apr 27 23:16:33 CST 2021, time=2021-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944191, encodeId=123b194419170, content=<a href='/topic/show?id=8194404117b' target=_blank style='color:#2F92EE;'>#囊胚移植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40411, encryptionId=8194404117b, topicName=囊胚移植)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1f1d390, createdName=feifers, createdTime=Sat Feb 20 15:16:33 CST 2021, time=2021-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044149, encodeId=c6c92044149c7, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Tue Jun 01 11:16:33 CST 2021, time=2021-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1315471, encodeId=c68913154e1eb, content=<a href='/topic/show?id=6fcc83e0554' target=_blank style='color:#2F92EE;'>#胚胎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83705, encryptionId=6fcc83e0554, topicName=胚胎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6393434, createdName=ailian1202, createdTime=Sun Jul 26 15:16:33 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1392969, encodeId=5fce1392969f7, content=<a href='/topic/show?id=8c9f4492370' target=_blank style='color:#2F92EE;'>#妊娠结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44923, encryptionId=8c9f4492370, topicName=妊娠结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fa82500120, createdName=12498a1cm67暂无昵称, createdTime=Sun Jul 26 15:16:33 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1514580, encodeId=0fc8151458019, content=<a href='/topic/show?id=690283e36cb' target=_blank style='color:#2F92EE;'>#胚胎移植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83736, encryptionId=690283e36cb, topicName=胚胎移植)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8a9910663000, createdName=ms2694732865965676, createdTime=Sun Jul 26 15:16:33 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1539936, encodeId=38241539936a2, content=<a href='/topic/show?id=98013806437' target=_blank style='color:#2F92EE;'>#受精#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38064, encryptionId=98013806437, topicName=受精)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=072113156483, createdName=旅苦化文_212, createdTime=Sun Jul 26 15:16:33 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=804553, encodeId=d404804553ec, content=了解一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Sat Jul 25 22:26:11 CST 2020, time=2020-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=804539, encodeId=c2d98045395f, content=有意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=116f5402036, createdName=ms9000000268923470, createdTime=Sat Jul 25 18:40:55 CST 2020, time=2020-07-25, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1813183, encodeId=d67d181318368, content=<a href='/topic/show?id=1fdd91e56f7' target=_blank style='color:#2F92EE;'>#试管婴#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91756, encryptionId=1fdd91e56f7, topicName=试管婴)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11b4465, createdName=ying_wu, createdTime=Tue Apr 27 23:16:33 CST 2021, time=2021-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944191, encodeId=123b194419170, content=<a href='/topic/show?id=8194404117b' target=_blank style='color:#2F92EE;'>#囊胚移植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40411, encryptionId=8194404117b, topicName=囊胚移植)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1f1d390, createdName=feifers, createdTime=Sat Feb 20 15:16:33 CST 2021, time=2021-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044149, encodeId=c6c92044149c7, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Tue Jun 01 11:16:33 CST 2021, time=2021-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1315471, encodeId=c68913154e1eb, content=<a href='/topic/show?id=6fcc83e0554' target=_blank style='color:#2F92EE;'>#胚胎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83705, encryptionId=6fcc83e0554, topicName=胚胎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6393434, createdName=ailian1202, createdTime=Sun Jul 26 15:16:33 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1392969, encodeId=5fce1392969f7, content=<a href='/topic/show?id=8c9f4492370' target=_blank style='color:#2F92EE;'>#妊娠结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44923, encryptionId=8c9f4492370, topicName=妊娠结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fa82500120, createdName=12498a1cm67暂无昵称, createdTime=Sun Jul 26 15:16:33 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1514580, encodeId=0fc8151458019, content=<a href='/topic/show?id=690283e36cb' target=_blank style='color:#2F92EE;'>#胚胎移植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83736, encryptionId=690283e36cb, topicName=胚胎移植)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8a9910663000, createdName=ms2694732865965676, createdTime=Sun Jul 26 15:16:33 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1539936, encodeId=38241539936a2, content=<a href='/topic/show?id=98013806437' target=_blank style='color:#2F92EE;'>#受精#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38064, encryptionId=98013806437, topicName=受精)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=072113156483, createdName=旅苦化文_212, createdTime=Sun Jul 26 15:16:33 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=804553, encodeId=d404804553ec, content=了解一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Sat Jul 25 22:26:11 CST 2020, time=2020-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=804539, encodeId=c2d98045395f, content=有意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=116f5402036, createdName=ms9000000268923470, createdTime=Sat Jul 25 18:40:55 CST 2020, time=2020-07-25, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1813183, encodeId=d67d181318368, content=<a href='/topic/show?id=1fdd91e56f7' target=_blank style='color:#2F92EE;'>#试管婴#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91756, encryptionId=1fdd91e56f7, topicName=试管婴)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11b4465, createdName=ying_wu, createdTime=Tue Apr 27 23:16:33 CST 2021, time=2021-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944191, encodeId=123b194419170, content=<a href='/topic/show?id=8194404117b' target=_blank style='color:#2F92EE;'>#囊胚移植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40411, encryptionId=8194404117b, topicName=囊胚移植)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1f1d390, createdName=feifers, createdTime=Sat Feb 20 15:16:33 CST 2021, time=2021-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044149, encodeId=c6c92044149c7, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Tue Jun 01 11:16:33 CST 2021, time=2021-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1315471, encodeId=c68913154e1eb, content=<a href='/topic/show?id=6fcc83e0554' target=_blank style='color:#2F92EE;'>#胚胎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83705, encryptionId=6fcc83e0554, topicName=胚胎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6393434, createdName=ailian1202, createdTime=Sun Jul 26 15:16:33 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1392969, encodeId=5fce1392969f7, content=<a href='/topic/show?id=8c9f4492370' target=_blank style='color:#2F92EE;'>#妊娠结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44923, encryptionId=8c9f4492370, topicName=妊娠结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fa82500120, createdName=12498a1cm67暂无昵称, createdTime=Sun Jul 26 15:16:33 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1514580, encodeId=0fc8151458019, content=<a href='/topic/show?id=690283e36cb' target=_blank style='color:#2F92EE;'>#胚胎移植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83736, encryptionId=690283e36cb, topicName=胚胎移植)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8a9910663000, createdName=ms2694732865965676, createdTime=Sun Jul 26 15:16:33 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1539936, encodeId=38241539936a2, content=<a href='/topic/show?id=98013806437' target=_blank style='color:#2F92EE;'>#受精#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38064, encryptionId=98013806437, topicName=受精)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=072113156483, createdName=旅苦化文_212, createdTime=Sun Jul 26 15:16:33 CST 2020, time=2020-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=804553, encodeId=d404804553ec, content=了解一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Sat Jul 25 22:26:11 CST 2020, time=2020-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=804539, encodeId=c2d98045395f, content=有意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=116f5402036, createdName=ms9000000268923470, createdTime=Sat Jul 25 18:40:55 CST 2020, time=2020-07-25, status=1, ipAttribution=)]
    2020-07-25 wxl882001

    了解一下

    0

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    2020-07-25 ms9000000268923470

    有意义

    0

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