J Rheumatol:中国多发性大动脉炎患者心脏受累的临床特征

2017-08-21 xiangting MedSci原创

伴有心脏异常的TA患者并不罕见,特别是伴Numano V型血管受累的患者。

这项研究旨在分析中国多发性大动脉炎(TA)患者心脏受累的特点。

回顾性分析了411例TA患者(325例女性,86例男性)的医疗数据。对伴有(n = 164)和不伴(n = 247)心脏受累TA患者的临床表现进行比较。

411例TA患者发病年龄的中位数为23.0岁(18.0-30.0),164例心脏受累患者的中位年龄23.0岁(17.3-30.0)。心脏受累组的病程(中位数:24.0 mos)显著长于无心脏受累患者(对照组,中位数:16.0 mos)。高血压(57.3%vs 46.6%; p = 0.033),肾功能不全(17.1%vs 7.7%; p = 0.003),锁骨下动脉杂音(45.1%vs 34.4%; p = 0.029)在心脏受累组更为常见。心脏受累组中134例(81.7%)患者出现瓣膜异常,26例(15.9%)心肌异常,19例(11.6%)冠状动脉异常。有心肌、瓣膜、冠脉异常患者的发病年龄(yrs)和病程(mos)分别为18.8/ 13.0,23.8/23.5和26.8/57.0。在心脏受累组中,心肌异常的22例(84.6%),冠脉异常的15例(78.9%),瓣膜异常的89例(66.4%)有Numano V型血管受累。高敏C反应蛋白水平在心脏受累组(中位数:10.0 mg/l)较高,与对照组相比差异有统计学意义(中位数7.0 mg/l; p = 0.017)。

伴有心脏异常的TA患者并不罕见,特别是伴Numano V型血管受累的患者。因此超声心动图检查可能是了解TA患者整体特征的有用工具。

原始出处:
Jing Li, Hongchao Li, Fei Sun, et al. Clinical Characteristics of Heart Involvement in Chinese Patients with Takayasu Arteritis. J Rheumatol. 15 August 2017. 

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    2018-06-16 xsm927
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    2017-08-21 1771ae4158m

    学习一下很不错

    0

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    2017-08-21 1dd8c52fm63(暂无匿称)

    学习学习,了解了解

    0