Chin Circul J:大于80岁高危急性心梗患者介入前预防性IABP有助于预防严重事件

2017-04-25 文韬 中国循环杂志

近期阜外医院张沛等在《中国循环杂志》发表的一项回顾性研究显示,在80岁以上的高危急性心梗患者中,急诊冠脉介入术前预防性置入主动脉内球囊反搏(IABP)减有助于预防严重心血管事件,但对长期生存率影响不大。IABP是一种机械辅助循环的方法,通过物理作用,提高主动脉内舒张压,增加冠状动脉供血和改善心肌功能。作者分析了99例>80岁的急性心梗患者,其中24例预防性植入了IABP。在73例未植入IAB

近期阜外医院张沛等在《中国循环杂志》发表的一项回顾性研究显示,在80岁以上的高危急性心梗患者中,急诊冠脉介入术前预防性置入主动脉内球囊反搏(IABP)减有助于预防严重心血管事件,但对长期生存率影响不大。

IABP是一种机械辅助循环的方法,通过物理作用,提高主动脉内舒张压,增加冠状动脉供血和改善心肌功能。

作者分析了99例>80岁的急性心梗患者,其中24例预防性植入了IABP。

在73例未植入IABP的患者中,有12例在术中或术后即刻、因血流动力学不稳定或反复室速和室颤而置入IABP。

多因素回归分析显示收缩压≤ 100 mmHg和非“罪犯”血管慢性闭塞是医生使用预防性IABP的独立预测因素,反映了术者对其血流动力学不稳定趋势的预判。

研究中预防性使用IABP的患者在1月时,有2人死亡(8.3%),有3人(12.5%)发生心原性休克,而未植入IABP和补救性IABP的患者分别有12人(16.4%)和2人(16.7%)死亡,有7人(9.6%)和3人(25%)心原性休克。

而术后TIMI血流<3级和合并疾病(包括慢阻肺、肾功能损害和贫血)等是长期随访过程中死亡的主要预测因素。

原始出处:

张沛, 戴军, 吴元,等. 直接经皮冠状动脉介入治疗前预防性置入主动脉内球囊反搏对大于80 岁急性ST 段抬高型心肌梗死患者的预后影响. 中国循环杂志, 2017, 32: 217-221.

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