BMJ:新冠肺炎感染孕妇的临床特征研究

2020-09-25 网络 网络

研究认为,新冠肺炎感染孕妇的发热和肌痛症状不显著,但接受重症监护治疗的风险增加。既往共病、高龄产妇和高体重指数是重症covid-19的危险因素

近日研究人员考察了疑似或确诊的2019年冠状病毒病(covid-19)孕妇的临床表现、危险因素、以及孕产妇和围产期结局。

本次研究为系统综述及荟萃分析研究,收集了Medline、Embase、Cochran、WHO COVID-19数据库、CNKI及万方数据库数据。研究报告了疑似或确诊covid-19孕妇的发病率、临床表现(症状、实验室和放射学发现)、危险因素以及围产期结局。

本次研究包含77项队列研究,11432名孕妇被诊断为疑似或确诊covid-19患者。妊娠期covid-19最常见的临床表现为发热(40%)和咳嗽(39%)。与育龄期的非孕妇相比,covid-19孕妇出现发热症状(比值比0.43)和肌痛(0.48)的风险较低,但需重症监护治疗(1.62)和有创通气(1.88)的风险增加。73名确诊为covid-19的孕妇(0.1%)死亡。年龄增加(1.78)、高体重指数(2.38)、慢性高血压(2.0)和糖尿病(2.51)与妊娠期严重的covid-19相关。既往共病是需重症监护(4.21)和有创通气(4.48)的危险因素。Covid-19产妇的自然早产率为6%。与未患covid-19的孕妇相比,患有covid-19孕妇的早产风险较高(3.01)。1/4的患有covid-19产妇的新生儿接受NICU护理(25%),其入院风险(风险比3.13)显著增加。

研究认为,新冠肺炎感染孕妇的发热和肌痛症状不显著,但接受重症监护治疗的风险增加。既往共病、高龄产妇和高体重指数是重症covid-19的危险因素。

原始出处:

John Allotey et al Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis. BMJ. 01 September,2020.

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    2021-01-09 智慧医人
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    2021-03-16 zhwj
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    2020-09-28 ms8000000775044569

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    2020-09-26 ms3000001774039970

    xie

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    2020-09-25 公卫新人

    新冠肺炎,疫情何时才能消失

    0