一口气看懂「糖尿病酮症酸中毒」

2016-07-17 Mechront MedSci原创

昨日扬子晚报刊登了一则名为「天气热不吃饭只吃饮料和冰块 男子患病死亡」的新闻。 习惯了北方气候的乔某因南方气温攀升,感身体疲乏无力、不思饮食。为消暑降温,在三四天时间里,没有正常进食,只吃饮料和冰块,结果更让他身体虚弱、胃部灼痛。后去医院就诊,但最终死亡。诊断为「糖尿病酮症酸中毒」。 「酮症酸中毒」是什么? 酮体是脂肪分解的代谢产物,为酸性物质,尿液可以排除一部分

昨日扬子晚报刊登了一则名为「天气热不吃饭只吃饮料和冰块 男子患病死亡」的新闻。



习惯了北方气候的乔某因南方气温攀升,感身体疲乏无力、不思饮食。为消暑降温,在三四天时间里,没有正常进食,只吃饮料和冰块,结果更让他身体虚弱、胃部灼痛。后去医院就诊,但最终死亡。诊断为糖尿病酮症酸中毒」



「酮症酸中毒」是什么?

酮体是脂肪分解的代谢产物,为酸性物质,尿液可以排除一部分该物质;但当其在血液中积蓄过多时,会引起酸中毒,即酮症酸中毒。

但凡会导致脂肪分解过多的情况,就会引发酮体浓度的增高;如体内胰岛素不足、机体缺乏糖分。

糖尿病酮症酸中毒」是什么?

糖尿病患者在某些情况下,因体内胰岛素严重不足,以及胰高血糖素、肾上腺素、皮质醇等升糖激素升高,导致高血糖、高血酮和代谢性酸中毒为主要改变的临床综合征。

该疾病是临床常见的糖尿病急性并发症之一,需及时治疗,不然后果会像新闻中男子一样,危及生命。

「糖尿病酮症酸中毒」会在什么情况下诱发?

落脚点在于胰岛素不足、升糖激素升高上,任何会加剧这两种情况的现象均会诱发该疾病。

常见诱因有饮食不当(如暴饮暴食、过度饥饿)、过度激烈运动、急性感染、应激、治疗性胰岛素停用或减量不当。

「糖尿病酮症酸中毒」会有什么表现?

最初糖尿病本身症状(口渴、多饮、多尿、疲乏无力等)会加重,同时伴胃肠道症状(食欲不振、恶心、呕吐、腹痛等)。

疾病进展后,出现脱水症状(脱水达体重5%:尿量减少、皮肤干燥、眼球下陷等;脱水超过15%:心率加快、脉搏细弱、血压及体温下降等),呼气中带有类似烂苹果气味的酮臭味。

病情进一步恶化,患者出现神志改变(头痛、嗜睡、意识不清甚至昏迷)。

「糖尿病酮症酸中毒」怎么诊断?

核心条件:

血糖 ≥ 16.7 mmol/L、尿酮体强阳性(+++~++++)或血酮>5mmol/L、血pH值<7.35或HCO-3<15 mmol/L,并排除酸中毒其他原因。

其他要点:

糖尿病病史或既往糖尿病酮症酸中毒病史、前面所述诱发该疾病的常见诱因、上述临床表现,以及电解质、心电图等辅助检查。

「糖尿病酮症酸中毒」怎么处理?

充足补液(稀释血酮、促进酮体经肾排泄)、小剂量胰岛素治疗(抑制酮体生成;避免低血糖及低血钾;当血糖降至13.9mmol/L时开始输入5%葡萄糖液)、纠正电解质及酸碱平衡失调、治疗诱因、防治并发症。

「糖尿病酮症酸中毒」怎么预防?

避免饮食不当,切忌过度饥饿或暴饮暴食;避免过度运动;多饮水避免脱水的发生;定期监测血糖,规律用药;减量、停药等应在医师的指导下进行;如有不适,及时就诊。

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    2017-06-24 QFXL123456

    归纳的好,学习了,谢谢

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  4. 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  5. 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objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 16:15:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93774, encodeId=fd8593e74de, content=知识点很好,值得普及!, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Jul 20 11:19:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1288676, encodeId=9d0112886e669, content=<a href='/topic/show?id=b969e679974' target=_blank style='color:#2F92EE;'>#糖尿病酮症酸中毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76799, encryptionId=b969e679974, topicName=糖尿病酮症酸中毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8346212, createdName=respect, createdTime=Tue Jul 19 04:56:00 CST 2016, time=2016-07-19, status=1, ipAttribution=)]
    2016-09-20 1e10c84am36(暂无匿称)

    文章很好,非常有益

    0

  6. 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objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 16:15:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93774, encodeId=fd8593e74de, content=知识点很好,值得普及!, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Jul 20 11:19:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1288676, encodeId=9d0112886e669, content=<a href='/topic/show?id=b969e679974' target=_blank style='color:#2F92EE;'>#糖尿病酮症酸中毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76799, encryptionId=b969e679974, topicName=糖尿病酮症酸中毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8346212, createdName=respect, createdTime=Tue Jul 19 04:56:00 CST 2016, time=2016-07-19, status=1, ipAttribution=)]
    2016-09-13 舒心和人

    生活方式很重要,感谢分享

    0

  7. 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createdBy=c5dd27335710, createdName=hywen7335, createdTime=Sat Apr 08 00:56:00 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2037515, encodeId=36dd203e515f5, content=<a href='/topic/show?id=862b9553521' target=_blank style='color:#2F92EE;'>#酮症酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95535, encryptionId=862b9553521, topicName=酮症酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c6262500044, createdName=1249862am72(暂无昵称), createdTime=Thu Jun 22 04:56:00 CST 2017, time=2017-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1641180, encodeId=c17b1641180de, content=<a href='/topic/show?id=8d739553475' target=_blank style='color:#2F92EE;'>#酮症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95534, encryptionId=8d739553475, topicName=酮症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=790822763597, createdName=ms705947299214030, createdTime=Fri Feb 03 09:56:00 CST 2017, time=2017-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=131813, encodeId=8c9513181369, content=文章很好,非常有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 20 22:39:00 CST 2016, time=2016-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=125638, encodeId=1a0212563825, content=生活方式很重要,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Tue Sep 13 19:00:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=106054, encodeId=40c31060542a, content=深度好文,值得学习,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sun Aug 28 04:01:00 CST 2016, time=2016-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105669, encodeId=f5651056693e, content=好文,值得学习,赞一个。, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 16:15:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93774, encodeId=fd8593e74de, content=知识点很好,值得普及!, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Jul 20 11:19:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1288676, encodeId=9d0112886e669, content=<a href='/topic/show?id=b969e679974' target=_blank style='color:#2F92EE;'>#糖尿病酮症酸中毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76799, encryptionId=b969e679974, topicName=糖尿病酮症酸中毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8346212, createdName=respect, createdTime=Tue Jul 19 04:56:00 CST 2016, time=2016-07-19, status=1, ipAttribution=)]
    2016-08-28 ylzr123

    深度好文,值得学习,赞!

    0

  8. 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objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 16:15:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93774, encodeId=fd8593e74de, content=知识点很好,值得普及!, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Jul 20 11:19:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1288676, encodeId=9d0112886e669, content=<a href='/topic/show?id=b969e679974' target=_blank style='color:#2F92EE;'>#糖尿病酮症酸中毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76799, encryptionId=b969e679974, topicName=糖尿病酮症酸中毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8346212, createdName=respect, createdTime=Tue Jul 19 04:56:00 CST 2016, time=2016-07-19, status=1, ipAttribution=)]
    2016-08-27 ylzr123

    好文,值得学习,赞一个。

    0

  9. 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objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 16:15:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93774, encodeId=fd8593e74de, content=知识点很好,值得普及!, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Wed Jul 20 11:19:00 CST 2016, time=2016-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1288676, encodeId=9d0112886e669, content=<a href='/topic/show?id=b969e679974' target=_blank style='color:#2F92EE;'>#糖尿病酮症酸中毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76799, encryptionId=b969e679974, topicName=糖尿病酮症酸中毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8346212, createdName=respect, createdTime=Tue Jul 19 04:56:00 CST 2016, time=2016-07-19, status=1, ipAttribution=)]
    2016-07-20 1dd8c52fm63(暂无匿称)

    知识点很好,值得普及!

    0

  10. 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