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J Rheumatol：成年男性胸椎弥漫性特发性骨肥厚的自然病程

2018-04-30 xiangting MedSci原创

弥漫性特发性骨肥厚病程DISH骨桥
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在5年的平均病程中，新骨从不完整的尖骨桥进展为更流动的完整骨桥。这表明可测量的成骨过程在继续发展，DISH确诊病例也是如此。

弥漫性特发性骨肥厚（DISH）的特征是脊柱右侧的流动骨桥。目前人们关于这些脊柱桥进展的认知很有限。这项纵向计算机断层扫描（CT）研究旨在弥补这一差距。该研究回顾性纳入胸部CT扫描2次（两次间隔≥2.5年）的老年男性患者。使用Resnick标准，分为前DISH组和确诊DISH组。创建了基于骨桥完整性（得分0-3）、流畅程度和新骨位置的评分系统以评估成骨进展。1367名受试者中的145名被分配到DISH组，平均随访5年。完整骨桥的患病率在前DISH组（11.3％至31.0％）和确诊DISH组（45.0％至55.8％）中均升高。前DISH组和确诊DISH组中平均骨桥评分均显著升高（p<0.001）。新骨逐渐变得更流动并周向扩大。在5年的平均病程中，新骨从不完整的尖骨桥进展为更流动的完整骨桥。这表明可测量的成骨过程在继续发展，DISH确诊病例也是如此。原始出处：Jonneke S. Kuperus, et al. The Natural Course of Diffuse Idiopathic Skeletal Hyperostosis in the Thoracic Spine of

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    2018-08-23 siiner

    #自然病程#

    0

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    2018-08-04 xinxin088

    #特发性#

    0

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    2018-09-17 123d9fd9m15暂无昵称

    学习

    0

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    2018-09-14 123d9fd9m15暂无昵称

    受教了

    0

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    2018-05-02 zhouqu_8

    #弥漫性#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1740365, encodeId=a8361e4036593, content=<a href='/topic/show?id=6f088626603' target=_blank style='color:#2F92EE;'>#自然病程#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86266, encryptionId=6f088626603, topicName=自然病程)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e00d34741921, createdName=siiner, createdTime=Thu Aug 23 22:14:00 CST 2018, time=2018-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1894666, encodeId=a095189466695, content=<a href='/topic/show?id=e45b6e859f3' target=_blank style='color:#2F92EE;'>#特发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67859, encryptionId=e45b6e859f3, topicName=特发性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=xinxin088, createdTime=Sat Aug 04 00:14:00 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=345325, encodeId=1d353453251d, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7ca22442437, createdName=123d9fd9m15暂无昵称, createdTime=Mon Sep 17 08:14:10 CST 2018, time=2018-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344983, encodeId=c51d344983aa, content=受教了, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7ca22442437, createdName=123d9fd9m15暂无昵称, createdTime=Fri Sep 14 14:45:38 CST 2018, time=2018-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1438586, encodeId=83a11438586f4, content=<a href='/topic/show?id=9851500416c' target=_blank style='color:#2F92EE;'>#弥漫性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50041, encryptionId=9851500416c, topicName=弥漫性)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Wed May 02 01:14:00 CST 2018, time=2018-05-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1489968, encodeId=41b2148996833, content=<a href='/topic/show?id=2d258411ea9' target=_blank style='color:#2F92EE;'>#胸椎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84117, encryptionId=2d258411ea9, topicName=胸椎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6d688662973, createdName=yyj065, createdTime=Wed May 02 01:14:00 CST 2018, time=2018-05-02, status=1, ipAttribution=)]
    2018-05-02 yyj065

    #胸椎#

    0