Prostate Cancer P D:下尿路症状对死亡率的影响

2018-11-16 AlexYang MedSci原创

下尿路症状(LUTS)作为死亡率风险因素的使用情况仍旧不清楚。考虑到症状的波动和症状的重新复发,重复性的评估师需要的。最近,有研究人员在中年和老年男性中,评估了与3种尿路储存相关的死亡率,包括紧急情况,白天尿频和夜尿情况,同时也考虑了跟踪调查期间,其他的随时间变化的因素。研究人员在芬兰进行了基于群体的通信调查,时间分别为 1994, 1999, 2004和2009年,跟踪调查起始年龄分别为50、6

下尿路症状(LUTS)作为死亡率风险因素的使用情况仍旧不清楚。考虑到症状的波动和症状的重新复发,重复性的评估师需要的。

最近,有研究人员在中年和老年男性中,评估了与3种尿路储存相关的死亡率,包括紧急情况,白天尿频和夜尿情况,同时也考虑了跟踪调查期间,其他的随时间变化的因素。研究人员在芬兰进行了基于群体的通信调查,时间分别为 1994, 1999, 2004和2009年,跟踪调查起始年龄分别为50、60和70岁。研究人员发现,在1332名符合标准的具有LUTS数据的男性中,514名(38.6%)男性在21年的跟踪调查过程中死亡。在时间依赖的分析中,白天尿频和夜尿与死亡率的增加显著相关:调整后白天尿频、夜尿和紧急情况的HR分别为 1.42 (95% CI 1.11-1.83) 、1.38 (1.07-1.79)和1.19 (0.94-1.50)。在敏感度分析中,只有夜尿与死亡的增加相关:调整后白天尿频、夜尿和紧急情况的HR分别为 1.09 (0.84-1.42)、1.41 (0.99-2.02)和0.94 (0.52-1.68)。

最后,研究人员指出,在老龄化男性中,LUTS在预测短期死亡率上要比长期死亡率更准确。重复性的评估是需要的,从而来检测临床相关性和永久性症状,这些常常与病态相关。另外,具有白天尿频和夜尿的男性的死亡率要增加1.4倍,因此在阐释伴随疾病时应该评估。

原始出处:

Jonne Åkerla, Jori S Pesonen, Antti Pöyhönen et al. Impact of lower urinary tract symptoms on mortality: a 21-year follow-up among middle-aged and elderly Finnish men. Prostate Cancer P D. 08 Nov 2018.

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    2018-11-18 lsndxfj
  5. [GetPortalCommentsPageByObjectIdResponse(id=2003788, encodeId=c6792003e8854, content=<a href='/topic/show?id=d82d4e52095' target=_blank style='color:#2F92EE;'>#尿路症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47520, encryptionId=d82d4e52095, topicName=尿路症状)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bfa6343, createdName=aliceclz, createdTime=Mon Aug 12 14:46:00 CST 2019, time=2019-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1791556, encodeId=f0aa1e9155698, content=<a href='/topic/show?id=b77f14e4541' target=_blank style='color:#2F92EE;'>#Prostate Ca#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14745, encryptionId=b77f14e4541, topicName=Prostate Ca)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a691420, createdName=30397604, createdTime=Thu Dec 06 13:46:00 CST 2018, time=2018-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1746847, encodeId=a4f41e468479c, content=<a href='/topic/show?id=05dc201464d' target=_blank style='color:#2F92EE;'>#下尿路#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20146, encryptionId=05dc201464d, topicName=下尿路)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=57c735864207, createdName=hongbochen, createdTime=Thu Mar 14 12:46:00 CST 2019, time=2019-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364417, encodeId=d72b136441eb9, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Sun Nov 18 03:46:00 CST 2018, time=2018-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1404528, encodeId=0cfd1404528c2, content=<a href='/topic/show?id=ce86201482f' target=_blank style='color:#2F92EE;'>#下尿路症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20148, encryptionId=ce86201482f, topicName=下尿路症状)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=edaf2479486, createdName=yilong5287543, createdTime=Sun Nov 18 03:46:00 CST 2018, time=2018-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1602077, encodeId=4be516020e768, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Sun Nov 18 03:46:00 CST 2018, time=2018-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=352771, encodeId=ffa0352e7166, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Fri Nov 16 13:54:10 CST 2018, time=2018-11-16, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=2003788, encodeId=c6792003e8854, content=<a href='/topic/show?id=d82d4e52095' target=_blank style='color:#2F92EE;'>#尿路症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47520, encryptionId=d82d4e52095, topicName=尿路症状)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bfa6343, createdName=aliceclz, createdTime=Mon Aug 12 14:46:00 CST 2019, time=2019-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1791556, encodeId=f0aa1e9155698, content=<a href='/topic/show?id=b77f14e4541' target=_blank style='color:#2F92EE;'>#Prostate Ca#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14745, encryptionId=b77f14e4541, topicName=Prostate Ca)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a691420, createdName=30397604, createdTime=Thu Dec 06 13:46:00 CST 2018, time=2018-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1746847, encodeId=a4f41e468479c, content=<a href='/topic/show?id=05dc201464d' target=_blank style='color:#2F92EE;'>#下尿路#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20146, encryptionId=05dc201464d, topicName=下尿路)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=57c735864207, createdName=hongbochen, createdTime=Thu Mar 14 12:46:00 CST 2019, time=2019-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364417, encodeId=d72b136441eb9, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Sun Nov 18 03:46:00 CST 2018, time=2018-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1404528, encodeId=0cfd1404528c2, content=<a href='/topic/show?id=ce86201482f' target=_blank style='color:#2F92EE;'>#下尿路症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20148, encryptionId=ce86201482f, topicName=下尿路症状)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=edaf2479486, createdName=yilong5287543, createdTime=Sun Nov 18 03:46:00 CST 2018, time=2018-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1602077, encodeId=4be516020e768, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Sun Nov 18 03:46:00 CST 2018, time=2018-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=352771, encodeId=ffa0352e7166, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Fri Nov 16 13:54:10 CST 2018, time=2018-11-16, status=1, ipAttribution=)]
    2018-11-18 sunylz
  7. [GetPortalCommentsPageByObjectIdResponse(id=2003788, encodeId=c6792003e8854, content=<a href='/topic/show?id=d82d4e52095' target=_blank style='color:#2F92EE;'>#尿路症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47520, encryptionId=d82d4e52095, topicName=尿路症状)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bfa6343, createdName=aliceclz, createdTime=Mon Aug 12 14:46:00 CST 2019, time=2019-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1791556, encodeId=f0aa1e9155698, content=<a href='/topic/show?id=b77f14e4541' target=_blank style='color:#2F92EE;'>#Prostate Ca#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14745, encryptionId=b77f14e4541, topicName=Prostate Ca)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a691420, createdName=30397604, createdTime=Thu Dec 06 13:46:00 CST 2018, time=2018-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1746847, encodeId=a4f41e468479c, content=<a href='/topic/show?id=05dc201464d' target=_blank style='color:#2F92EE;'>#下尿路#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20146, encryptionId=05dc201464d, topicName=下尿路)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=57c735864207, createdName=hongbochen, createdTime=Thu Mar 14 12:46:00 CST 2019, time=2019-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364417, encodeId=d72b136441eb9, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Sun Nov 18 03:46:00 CST 2018, time=2018-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1404528, encodeId=0cfd1404528c2, content=<a href='/topic/show?id=ce86201482f' target=_blank style='color:#2F92EE;'>#下尿路症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20148, encryptionId=ce86201482f, topicName=下尿路症状)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=edaf2479486, createdName=yilong5287543, createdTime=Sun Nov 18 03:46:00 CST 2018, time=2018-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1602077, encodeId=4be516020e768, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Sun Nov 18 03:46:00 CST 2018, time=2018-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=352771, encodeId=ffa0352e7166, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Fri Nov 16 13:54:10 CST 2018, time=2018-11-16, status=1, ipAttribution=)]
    2018-11-16 一个字-牛

    学习了谢谢分享

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