Neurology:癫痫全球患病率和发病率分析

2016-12-18 haofan MedSci原创

这项研究从发表的国际研究中得到了一个全面的综合的癫痫的患病率和发病率,并提供洞察估计之间的异质性的因素的机会。显著的差距(例如,缺乏发病率研究,按年龄组分层)被确定,进一步进行癫痫流行病学研究标准化报告是必要的。

近日,神经病学领域权威期刊Neurology上发表了一篇荟萃分析文章,旨在评价以人群为基础的癫痫全球患病率和发病率的研究,并通过荟萃分析技术来探讨可以用于解释估计两者之间的异质性的因素。

研究人员遵循了系统评价和Meta分析的优选报告条目标准,并检索了MEDLINE和EMBASE数据库,查找了自1985年至今发表关于癫痫患病率和发病率的文献。摘要、全文审查和数据抽提有两个研究者独立进行。采用Meta分析和Meta回归分析,探究患病率、发病率、年龄、性别、农村收入水平、研究质量之间的相关性。

研究人员共纳入222项研究(197项为患病率研究,48项为发病率研究)。活动性癫痫的患病率为每1000人有6.38人(95%可信区间为5.57-7.30),而终身患病率为每1000人有7.60人(95%可信区间为6.17-9.38)。每年癫痫的累积发病率为每100,000人有67.77人(95%可信区间为56.69-81.03),而发病率为每100,000人每年有61.44人(95%可信区间为50.75-74.38)。癫痫患病率不受年龄、性别、或研究质量影响。在中低收入国家的活动性年患病率、终生患病率和癫痫发病率均较高。不明病因的癫痫和全身性发作的癫痫的发病率最高。

由此可见,这项研究从发表的国际研究中得到了一个全面的综合的癫痫的患病率和发病率,并提供洞察估计之间的异质性的因素的机会。显著的差距(例如,缺乏发病率研究,按年龄组分层)被确定,进一步进行癫痫流行病学研究标准化报告是必要的。

原始出处:


Kirsten M.Fiest, et al. Prevalence and incidence of epilepsy A systematic
review and meta-analysis of international studies
. Neurology. December 16, 2016.  

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    2017-10-06 yinhl1978
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    2017-05-26 lifestar
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    2016-12-20 xinmeili
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    2016-12-20 Lisa971

    国民患病率,跟国家发展水平相关~

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1999792, encodeId=343d1999e926c, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Fri Oct 06 23:15:00 CST 2017, time=2017-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823299, encodeId=0980182329905, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Fri May 26 11:15:00 CST 2017, time=2017-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250448, encodeId=8130125044864, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Tue Dec 20 11:15:00 CST 2016, time=2016-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164195, encodeId=790c164195e6, content=国民患病率,跟国家发展水平相关~, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Tue Dec 20 00:13:44 CST 2016, time=2016-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164025, encodeId=6fb616402584, content=癫痫的发病率也在增加。, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160529/IMG574A6B851C0291840.jpg, createdBy=cb1b1723481, createdName=stomach, createdTime=Mon Dec 19 10:00:44 CST 2016, time=2016-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=163972, encodeId=2b5b1639e2bf, content=新的统计数据, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Dec 19 06:01:45 CST 2016, time=2016-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=163911, encodeId=aecb163911e1, content=学习中,希望有所进步, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Sun Dec 18 23:29:44 CST 2016, time=2016-12-18, status=1, ipAttribution=)]
    2016-12-19 stomach

    癫痫的发病率也在增加。

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1999792, encodeId=343d1999e926c, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Fri Oct 06 23:15:00 CST 2017, time=2017-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823299, encodeId=0980182329905, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Fri May 26 11:15:00 CST 2017, time=2017-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250448, encodeId=8130125044864, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Tue Dec 20 11:15:00 CST 2016, time=2016-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164195, encodeId=790c164195e6, content=国民患病率,跟国家发展水平相关~, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Tue Dec 20 00:13:44 CST 2016, time=2016-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164025, encodeId=6fb616402584, content=癫痫的发病率也在增加。, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160529/IMG574A6B851C0291840.jpg, createdBy=cb1b1723481, createdName=stomach, createdTime=Mon Dec 19 10:00:44 CST 2016, time=2016-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=163972, encodeId=2b5b1639e2bf, content=新的统计数据, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Dec 19 06:01:45 CST 2016, time=2016-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=163911, encodeId=aecb163911e1, content=学习中,希望有所进步, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Sun Dec 18 23:29:44 CST 2016, time=2016-12-18, status=1, ipAttribution=)]
    2016-12-19 susice

    新的统计数据

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1999792, encodeId=343d1999e926c, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Fri Oct 06 23:15:00 CST 2017, time=2017-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823299, encodeId=0980182329905, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Fri May 26 11:15:00 CST 2017, time=2017-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250448, encodeId=8130125044864, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Tue Dec 20 11:15:00 CST 2016, time=2016-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164195, encodeId=790c164195e6, content=国民患病率,跟国家发展水平相关~, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Tue Dec 20 00:13:44 CST 2016, time=2016-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=164025, encodeId=6fb616402584, content=癫痫的发病率也在增加。, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160529/IMG574A6B851C0291840.jpg, createdBy=cb1b1723481, createdName=stomach, createdTime=Mon Dec 19 10:00:44 CST 2016, time=2016-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=163972, encodeId=2b5b1639e2bf, content=新的统计数据, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Dec 19 06:01:45 CST 2016, time=2016-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=163911, encodeId=aecb163911e1, content=学习中,希望有所进步, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Sun Dec 18 23:29:44 CST 2016, time=2016-12-18, status=1, ipAttribution=)]
    2016-12-18 cqykthl

    学习中,希望有所进步

    0

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