ASCO更新止吐药临床实践指南

2011-10-04 MedSci原创 MedSci原创

  近日,美国临床肿瘤学会(ASCO)更新了止吐药临床实践指南,新指南在线发表于《临床肿瘤学杂志》(J Clin Oncol)。   新指南推荐:   蒽环类联合环磷酰胺应被归为重度致吐性化疗方案。   对于接受重度致吐性药物化疗的患者,应给予一种5羟色胺3(5-HT3)受体拮抗剂、地塞米松和一种神经激肽1(NK1)受体拮抗剂治疗。   一项大型研究证明福沙匹坦和阿瑞匹

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  近日,美国临床肿瘤学会(ASCO)更新了止吐药临床实践指南,新指南在线发表于《临床肿瘤学杂志》(J Clin Oncol)。

  新指南推荐:

  蒽环类联合环磷酰胺应被归为重度致吐性化疗方案。

  对于接受重度致吐性药物化疗的患者,应给予一种5羟色胺3(5-HT3)受体拮抗剂、地塞米松和一种神经激肽1(NK1)受体拮抗剂治疗。

  一项大型研究证明福沙匹坦和阿瑞匹坦有相同止吐效果。

  对于接受中度致吐性药物化疗的患者,应优先给予帕洛诺司琼而非其他药物,并联合地塞米松治疗。

  对于接受轻度致吐性药物化疗的患者,应在化疗开始前给予地塞米松。

  对于接受重度致吐性放疗的患者,应在每次放疗前并在放疗后24小时给予患者5-HT3受体拮抗剂,可在第1~5次放疗期间给予患者1疗程共5日的地塞米松治疗。

  指南更新委员会强调应在治疗过程中持续监测患者症状。医生常低估恶心的发生率,这一症状不如呕吐好控制。

  相关链接:Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update

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    2012-02-17 quxin068
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    2011-10-06 rgjl