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SABCS：乳腺癌干细胞对抗化疗和放疗的机制被初步揭开

2011-12-20 MedSci原创 MedSci原创

乳腺肿瘤干细胞乳腺癌干细胞
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美国贝勒医学院(Baylor College of Medicine)研究人员在2011年德克萨斯大学健康科学中心癌症治疗和研究中心-美国癌症研究协会圣安东尼奥市乳腺癌研讨会上陈述了他们在研究乳腺肿瘤干细胞---一小部分独特的乳腺癌细胞，能够启动肿瘤生长，并且相对而言能够抵抗化疗和放疗---方面取得的新进展，他们发现Stat3信号传导在肿瘤干细胞中高度活跃，另外还发现两种不同的Hedgehog信号

美国贝勒医学院(Baylor College of Medicine)研究人员在2011年德克萨斯大学健康科学中心癌症治疗和研究中心-美国癌症研究协会圣安东尼奥市乳腺癌研讨会上陈述了他们在研究乳腺肿瘤干细胞---一小部分独特的乳腺癌细胞，能够启动肿瘤生长，并且相对而言能够抵抗化疗和放疗---方面取得的新进展，他们发现Stat3信号传导在肿瘤干细胞中高度活跃，另外还发现两种不同的Hedgehog信号传导网络抑制剂组合使用时能够促进肿瘤萎缩。 贝勒医学院李斯特和休-史密斯乳腺中心成员迈克尔-刘易斯(Michael Lewis)也是一名分子和细胞生物学和放射学副教授，他说，“这是乳腺癌基础科学研究人员正努力解决的主要临床问题，以便更好地理解这些干细胞的分子特征。这些细胞似乎能造成疾病复发并扩散到身体上其他器官”。 Stat3信号传导刘易斯实验室研究生Wei Wei领导的一个研究人员小组在他们的研究摘要中写到，鉴定出负责乳腺癌干细胞维持和自我更新的细胞信号传导途径是开发有效疗法的一种关键性障碍。 在他们的研究中，研究小组集中关注一种重要的调节干细胞功能的途径，Stat3信号传导途径。 使用一种

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    2012-11-25 cmj21wellington

    #ABC#

    0

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    2012-04-28 ms7899726347904398

    #乳腺癌干细胞#

    0

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    2011-12-22 1249898am19暂无昵称

    #癌干细胞#

    0

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    2011-12-22 guguangxiang

    #SABCS#

    0