JAMA:化疗后一定要掉头发吗?新技术或可改变这一现状

2017-03-19 生物谷 生物谷

掉发是癌症治疗过程中最严重的副作用之一。而科学家们早在80年代就指出通过冷却患者的头皮,能够有效避免化疗过程中头发掉落的问题。2015年,一种叫做DigniCap的冷却设备被FDA批准用于女性乳腺癌治疗的过程中。


(图片摘自网络)
掉发是癌症治疗过程中最严重的副作用之一。而科学家们早在80年代就指出通过冷却患者的头皮,能够有效避免化疗过程中头发掉落的问题。2015年,一种叫做DigniCap的冷却设备被FDA批准用于女性乳腺癌治疗的过程中。

最近,发表在《Journal of the American Medical Association》杂志上的两篇文章指出这种设备具有显著的效果。结果显示,使用该设备的女性患者头发脱落的情况得到了50%的缓解。

那么,科学家们是如何想到利用冷却头皮达到保存头发的目的的呢,另外,这一疗法究竟又需要多久的时间呢?事实上,利用冷却的方法防止毛发脱落并不是新鲜的主意,过去三十年来已经有很多公司都在试验,也有一些设备早已在临床上使用。但这一设备是第一次得到了FDA的批准。在最近的临床试验中,作者们通过对接受化疗的早期乳腺癌患者进行试验,得到了令人满意的结果。

这种冷却设备的工作机制是什么?在化疗过程中,冷却头皮能够降低毛囊的血液流速,这会进一步降低化疗药物对毛囊的损伤作用,并进而减少头发的脱落。此前有许多设备已经在这一方面进行了尝试,但最新的这一设备采用了紧绷的头盖,就像一个浴帽一样,能够在化疗期间持续性的戴在头上,也避免了使用制冷设备或更换头套的麻烦。

这一设备真的对乳腺癌患者有益处吗?对于许多女性患者来说,化疗引发的头发脱落极大地影响了生活质量。另一方面,通过降低头发的脱落能够有效地降低患者在治疗期间的精神压力。

这一设备未来能否用于其他癌症的治疗呢?当然,针对不同的癌症类型会有不同的解决办法,不过研究者们相信这一设备能同样能够适用于其它类型的癌症。

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    2017-06-17 venlin
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    2017-03-21 qindq
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    2017-03-20 虈亣靌

    学习新知识谢谢分享

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