Int Ophthalmol. :用于近视的激光原位角膜磨镶术后眼内压和“眼内压常数”的样本预测模型

2017-06-26 cuiguizhong MedSci原创

激光原位角膜磨镶术术后对近视患者眼内压的评估很重要。本项研究就得出了近视患者激光原位角膜磨镶术术后借助近视眼中眼内压常数预测真实眼内压的一个实用公式。

近日,来自土耳其Acibadem大学医学院眼科系的Bahadir Kilavuzoglu AE和其合作者在Int Ophthalmol.杂志上发表了他们的最近研究:用于近视的激光原位角膜磨镶术后眼内压和“眼内压常数”的样本预测模型。

在本项研究中,作者们描述了一个近视治疗术--激光原位角膜磨镶术(LASIK)的眼内压(IOP)和眼内压常数的样本预测模型。

研究中回顾性地记录了通过WaveLight Allegretto Wave Eye-Q 400 Hz准分子激光和Hansatome XP微型角膜刀进行激光原位角膜磨镶术的近视和近视散光患者的治疗情况。除了近视或近视散光患者之外,没有全身或眼部疾病的患者也被纳入研究。收集术前和术后1个月数据和术中数据用于建立激光原位角膜磨镶术术后的眼内压预测模型。通过从术前眼内压中减去预测的眼内压计算眼内压常数。研究还利用配对样本t检验、Pearson相关分析、曲线估计分析和线性回归分析用于评估研究数据。

该项研究共纳入了平均年龄32±7.8岁的214位病人的425只眼睛。尝试矫正(SE-ac)的平均球面当量为-3.7±1.7屈光度。激光原位角膜磨镶术术后眼内压平均下降幅度为4.6±2.3 mmHg。术前和术后眼内压差异有统计学意义(P<0.001)。基于线性回归分析得出结果是,SE-ac(P<0.001和R 2= 0.043)、术前眼内压(P<0.001和R2= 0.370)和中心角膜厚度(P<0.001和R2=0.132)对术后眼内压具有非常显着的影响。由此,作者们创建了回归模型(F = 127.733,P <0.001),调整后的R2值为0.548。

激光原位角膜磨镶术术后对近视患者眼内压的评估很重要。本项研究就得出了近视患者激光原位角膜磨镶术术后借助近视眼中眼内压常数预测真实眼内压的一个实用公式。

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    2018-03-16 zhzhxiang
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    2017-06-30 半夏微凉

    学习了谢谢分享

    0

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    2017-06-28 oliver169
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    2017-06-28 snowpeakxu
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