CT血管造影原始图像预测性优于非增强CT

2011-07-03 MedSci原创 MedSci原创

一项最新的研究结果表明,与非增强CT ASPECTS评分(Alberta卒中项目早期CT评分)相比,CT血管造影原始图像ASPECTS评分与患者基线时的卒中严重程度更相关,因而它不仅是确定最终梗死组织范围的一个较好预测因子,还可以独立地预测患者神经系统的预后情况。该项研究成果已在线发表于《卒中》期刊网站。 Alberta卒中项目早期CT评分(ASPECTS)现已广泛应用于对急性卒中患者早期缺血病

一项最新的研究结果表明,与非增强CT ASPECTS评分(Alberta卒中项目早期CT评分)相比,CT血管造影原始图像ASPECTS评分与患者基线时的卒中严重程度更相关,因而它不仅是确定最终梗死组织范围的一个较好预测因子,还可以独立地预测患者神经系统的预后情况。该项研究成果已在线发表于《卒中》期刊网站。

Alberta卒中项目早期CT评分(ASPECTS)现已广泛应用于对急性卒中患者早期缺血病变的评估。我们假定,与非增强CT ASPECTS评分相比,CT血管造影原始图像(CTA-SI)ASPECTS评分与患者的基线国立卫生院卒中量表评分、最终ASPECTS评分以及神经病学预后之间的相关性更强。

科学家对来自Calgary CT血管造影数据库、患急性缺血性卒中且近端血管闭塞部位(颈内动脉、大脑中动脉M1段、大脑中动脉M2段近端)明确的患者进行了研究。患者的CT结果经三位检查人员独立判读后得出其基线非增强CT ASPECTS评分、CT血管造影原始图像ASPECTS评分以及随访期ASPECTS评分。患者的详细人口统计学数据和患病风险因素也被记录了下来。预后良好的评价标准是:随访3个月时的改良Rankin量表评分≤2分。

研究中共选取了261例近端血管闭塞患者进行分析。结果发现,CT血管造影原始图像ASPECTS评分(Spearman相关系数 r=0.65;95% 置信区间CI为0.58-0.72;P<0.001)与非增强CT ASPECTS评分(Spearman相关系数 r=0.46;95%CI为0.36-0.55;P<0.001)相比,前者与随访期CT ASPECTS评分之间的相关性更强。与非增强CT ASPECTS评分相比,CT血管造影原始图像ASPECTS评分与基线国立卫生院卒中量表评分和发病24小时后国立卫生院卒中量表评分之间的相关性更好(P<0.001)。在一种同时包含CT血管造影原始图像ASPECTS评分和非增强CT ASPECTS评分两因素在内的校正模型中,我们发现患者预后较好与其CT血管造影原始图像ASPECTS评分相关(比值比OR为2.30;95%CI为1.16-4.53),而与非增强CT ASPECTS评分不相关(OR为1.54;95%CI为0.84-2.82)。在多种影像学指标中,CT血管造影原始图像ASPECTS评分是患者预后良好的唯一一个独立预测因子(OR为2.29;95%CI为1.16-4.53)。

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  2. [GetPortalCommentsPageByObjectIdResponse(id=2034718, encodeId=a0c12034e18a2, content=<a href='/topic/show?id=79d099360d2' target=_blank style='color:#2F92EE;'>#非增强#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99360, encryptionId=79d099360d2, topicName=非增强)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=20b5274, createdName=JR19860219, createdTime=Sun Sep 04 21:21:00 CST 2011, time=2011-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1987050, encodeId=a31f198e050d5, content=<a href='/topic/show?id=a498422e7e6' target=_blank style='color:#2F92EE;'>#增强CT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42277, encryptionId=a498422e7e6, topicName=增强CT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc0372, createdName=bnurmamat, createdTime=Sat Dec 10 01:21:00 CST 2011, time=2011-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3364, encodeId=b122336400, content=I think you hit a bullseye there fleals!, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=jalen, createdTime=Wed Oct 19 19:34:00 CST 2011, time=2011-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3143, encodeId=eada31434f, content=这样的文章也能发表, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=98d945896, createdName=ximengchuixue, createdTime=Fri Sep 16 01:28:00 CST 2011, time=2011-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1493948, encodeId=e7ab1493948f7, content=<a href='/topic/show?id=3e34949e333' target=_blank style='color:#2F92EE;'>#造影#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94973, encryptionId=3e34949e333, topicName=造影)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=908d9134595, createdName=sodoo, createdTime=Tue Jul 05 14:21:00 CST 2011, time=2011-07-05, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2034718, encodeId=a0c12034e18a2, content=<a href='/topic/show?id=79d099360d2' target=_blank style='color:#2F92EE;'>#非增强#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99360, encryptionId=79d099360d2, topicName=非增强)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=20b5274, createdName=JR19860219, createdTime=Sun Sep 04 21:21:00 CST 2011, time=2011-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1987050, encodeId=a31f198e050d5, content=<a href='/topic/show?id=a498422e7e6' target=_blank style='color:#2F92EE;'>#增强CT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42277, encryptionId=a498422e7e6, topicName=增强CT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc0372, createdName=bnurmamat, createdTime=Sat Dec 10 01:21:00 CST 2011, time=2011-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3364, encodeId=b122336400, content=I think you hit a bullseye there fleals!, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=jalen, createdTime=Wed Oct 19 19:34:00 CST 2011, time=2011-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3143, encodeId=eada31434f, content=这样的文章也能发表, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=98d945896, createdName=ximengchuixue, createdTime=Fri Sep 16 01:28:00 CST 2011, time=2011-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1493948, encodeId=e7ab1493948f7, content=<a href='/topic/show?id=3e34949e333' target=_blank style='color:#2F92EE;'>#造影#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94973, encryptionId=3e34949e333, topicName=造影)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=908d9134595, createdName=sodoo, createdTime=Tue Jul 05 14:21:00 CST 2011, time=2011-07-05, status=1, ipAttribution=)]
    2011-10-19 jalen

    I think you hit a bullseye there fleals!

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2034718, encodeId=a0c12034e18a2, content=<a href='/topic/show?id=79d099360d2' target=_blank style='color:#2F92EE;'>#非增强#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99360, encryptionId=79d099360d2, topicName=非增强)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=20b5274, createdName=JR19860219, createdTime=Sun Sep 04 21:21:00 CST 2011, time=2011-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1987050, encodeId=a31f198e050d5, content=<a href='/topic/show?id=a498422e7e6' target=_blank style='color:#2F92EE;'>#增强CT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42277, encryptionId=a498422e7e6, topicName=增强CT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc0372, createdName=bnurmamat, createdTime=Sat Dec 10 01:21:00 CST 2011, time=2011-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3364, encodeId=b122336400, content=I think you hit a bullseye there fleals!, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=jalen, createdTime=Wed Oct 19 19:34:00 CST 2011, time=2011-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=3143, encodeId=eada31434f, content=这样的文章也能发表, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=98d945896, createdName=ximengchuixue, createdTime=Fri Sep 16 01:28:00 CST 2011, time=2011-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1493948, encodeId=e7ab1493948f7, content=<a href='/topic/show?id=3e34949e333' target=_blank style='color:#2F92EE;'>#造影#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94973, encryptionId=3e34949e333, topicName=造影)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=908d9134595, createdName=sodoo, createdTime=Tue Jul 05 14:21:00 CST 2011, time=2011-07-05, status=1, ipAttribution=)]
    2011-09-16 ximengchuixue

    这样的文章也能发表

    0

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    2011-07-05 sodoo