Obstet Gynecol:胎盘植入和产后出血

2015-03-17 MedSci MedSci原创

胎盘植入是产科凶险的并发症,无论妊娠或产时、产后均不易确诊,一旦发病致严重产后出血,如不及时、果断处理,会危及产妇生命。 近期Azar Mehrabadi等人进行了一项回顾性队列研究,以探究胎盘植入与产后出血及严重产后出血的发生率。该研究纳入了2009-2010年间在加拿大住院分娩的孕妇共570,637人,胎盘植入包括胎盘粘连在子宫壁(侵入性胎盘)、植入到子宫肌肉组织(植入性胎盘)和穿透子宫

胎盘植入是产科凶险的并发症,无论妊娠或产时、产后均不易确诊,一旦发病致严重产后出血,如不及时、果断处理,会危及产妇生命。

近期Azar Mehrabadi等人进行了一项回顾性队列研究,以探究胎盘植入与产后出血及严重产后出血的发生率。该研究纳入了2009-2010年间在加拿大住院分娩的孕妇共570,637人,胎盘植入包括胎盘粘连在子宫壁(侵入性胎盘)、植入到子宫肌肉组织(植入性胎盘)和穿透子宫附着在周围器官(穿透性胎盘)。严重产后出血包括进行输血治疗、子宫切除术、或者其他止血操作(子宫捆绑缝合、子宫动脉栓塞等)。

该研究数据表明,每10,000名孕妇中,胎盘植入发生率为14.4(95% CI 13.4–15.4)(819/570,637),胎盘植入合并产后出血的发生率为7.2(95% CI 6.5–8.0)。胎盘植入孕妇其产后出血主要集中在第三产程(41%)。尽管胎盘植入与产后出血密切相关(RR 8.3,95%
CI 7.7–8.9),但是其低频率导致人群中所占比例很小(1.0%, 95% CI 0.93–1.16)。不可忽视的是,胎盘植入和产后出血行子宫切除的风险密切相关(RR 286, 95% CI 226–361),其人口中所占比例为29.0% (95% CI 24.3–34.3)。

该研究表明,胎盘植入虽然不常见、发生率低,不能对近期增加的产后出血率做出合适的解释,但是胎盘植入具有潜在的产后出血行子宫切除术的风险。

原始出处:

Mehrabadi A1, Hutcheon JA, Liu S, Bartholomew S, Kramer MS, Liston RM, Joseph KS; for the Maternal Health Study Group of the Canadian Perinatal Surveillance System (Public Health Agency of Canada).Contribution of Placenta Accreta to the Incidence of Postpartum Hemorrhage and Severe Postpartum Hemorrhage.Obstet Gynecol. 2015 Mar 5. [Epub ahead of print]

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    2018-01-01 15121100f4m

    胎盘植入要做好围手术期出血和子宫切除准备.

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    2015-11-24 yhy100200
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  5. [GetPortalCommentsPageByObjectIdResponse(id=274440, encodeId=963a2e4440f7, content=胎盘植入要做好围手术期出血和子宫切除准备., beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/12/31/a88428e95e462b5a95499ced50b4325e.jpg, createdBy=60182225250, createdName=15121100f4m, createdTime=Mon Jan 01 09:32:00 CST 2018, time=2018-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2043844, encodeId=4c6420438448e, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Wed Jun 17 23:02:00 CST 2015, time=2015-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011182, encodeId=3401201118223, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Tue Nov 24 12:02:00 CST 2015, time=2015-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1659265, encodeId=91151659265e9, content=<a href='/topic/show?id=8c208366583' target=_blank style='color:#2F92EE;'>#胎盘植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83665, encryptionId=8c208366583, topicName=胎盘植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1f1e24955765, createdName=gwc391, createdTime=Fri Nov 13 11:02:00 CST 2015, time=2015-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=19225, encodeId=7a4a19225ad, content=然不常见、发生率低,不能对近期增加的产后出血率做出合适的解释,但是胎盘植入具有潜在的产后出血行子宫切除术的风, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Tue Mar 31 23:29:00 CST 2015, time=2015-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1404937, encodeId=f18a140493efe, content=<a href='/topic/show?id=4b552444e8c' target=_blank style='color:#2F92EE;'>#产后出血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24447, encryptionId=4b552444e8c, topicName=产后出血)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85fc2510054, createdName=gous, createdTime=Thu Mar 19 05:02:00 CST 2015, time=2015-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1406808, encodeId=895c1406808ff, content=<a href='/topic/show?id=2aca8365e2c' target=_blank style='color:#2F92EE;'>#胎盘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83657, encryptionId=2aca8365e2c, topicName=胎盘)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTItxfbnwF4Yku2j227me6wl2EGarBoTicR3tHxrMtib5tnyyEEsgxlHkk8JAS4ZjHsEF7PxhBwh1QwQ/132, createdBy=c8162575557, createdName=liuyong2981, createdTime=Thu Mar 19 05:02:00 CST 2015, time=2015-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520257, encodeId=bddc152025e57, content=<a href='/topic/show?id=7a736264553' target=_blank style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Thu Mar 19 05:02:00 CST 2015, time=2015-03-19, status=1, ipAttribution=)]
    2015-03-31 x35042875

    然不常见、发生率低,不能对近期增加的产后出血率做出合适的解释,但是胎盘植入具有潜在的产后出血行子宫切除术的风

    0

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    2015-03-19 gous
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    2015-03-19 jiyangfei

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