Radiology:CT表现预测结肠憩室炎复发的价值。

2017-08-29 shaosai MedSci原创

结肠憩室是指肠粘膜经肠壁肌层缺损处向外形成囊状突出的病理结构。多个憩室的存在则称之为结肠憩室病。憩室绝大多数为后天形成的。结肠憩室炎急性发作时有程度不同的局限性腹部疼痛,可呈刺痛、钝痛和绞痛,大多疼痛部位都在左下腹,偶尔位于耻骨上、右下腹或整个下腹部。炎症邻接膀胱可产生尿频、尿急。根据炎症部位和严重性还可伴有恶心和呕吐。本研究旨在评价CT表现预测结肠憩室炎复发的价值并将结果发表在Radiology

结肠憩室是指肠粘膜经肠壁肌层缺损处向外形成囊状突出的病理结构。多个憩室的存在则称之为结肠憩室病。憩室绝大多数为后天形成的。结肠憩室炎急性发作时有程度不同的局限性腹部疼痛,可呈刺痛、钝痛和绞痛,大多疼痛部位都在左下腹,偶尔位于耻骨上、右下腹或整个下腹部。炎症邻接膀胱可产生尿频、尿急。根据炎症部位和严重性还可伴有恶心和呕吐。本研究旨在评价CT表现预测结肠憩室炎复发的价值并将结果发表在Radiology上。

本研究共纳入了自2004年1月至2008年5月诊断为急性结肠憩室炎的患者,并安排6位腹部组影像科医师评价结肠憩室炎的病变位置、病变处最大管壁厚度、憩室炎的严重程度、其他并发症(脓肿、瘘管、狭窄和穿孔)、炎性病变程度。分析自患者初次行CT检查后5年的病历来评估临床预后。利用单变量和多变量COX比例危险回归模型来评价憩室炎的复发指标。

结果为,结肠憩室炎最常见于直肠乙状结肠(70%, 309 of 440)和降结肠(30%, 133 of 440)。

共有22%患者(98 of 440)表现为复杂的憩室炎。在单变量回归分析中,结肠憩室炎复发最显着的预测指标为炎性病变处的最大管壁厚度(管壁厚度每增加1毫米HR为1.07 ,P < .001)、合并并发症(HR, 1.75; P = .002)和炎性程度(每增加1个等级HR为1.36,线性趋势P为0.003)。在炎性病变的最大管壁厚度(HR, 1.05 per millimeter; P = .016)、炎性程度(HR, 1.29 per category; P = .018)在Cox多变量回归模型中仍然具有显着性差异。

本研究表明,结肠的最大管壁厚度和炎性程度是急性结肠憩室炎复发的预测指标,从而有助于根据选择性结肠部分切除术的需要指导治疗方案。

原始出处:

Dickerson EC, Chong ST, Ellis JH, et al,Recurrence of Colonic Diverticulitis: Identifying Predictive CT Findings-Retrospective Cohort Study. Radiology. 2017.DOI: 10.1148/radiol.2017161374

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1391439, encodeId=eb171391439fb, content=<a href='/topic/show?id=b5be53e91fc' target=_blank style='color:#2F92EE;'>#憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53791, encryptionId=b5be53e91fc, topicName=憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Aug 31 11:57:00 CST 2017, time=2017-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522716, encodeId=5def1522e169f, content=<a href='/topic/show?id=14d853e8918' target=_blank style='color:#2F92EE;'>#憩室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53789, encryptionId=14d853e8918, topicName=憩室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=33b211483971, createdName=zutt, createdTime=Thu Aug 31 11:57:00 CST 2017, time=2017-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523804, encodeId=43bd15238045c, content=<a href='/topic/show?id=7170e87563e' target=_blank style='color:#2F92EE;'>#结肠憩室炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78756, encryptionId=7170e87563e, topicName=结肠憩室炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4e5311558208, createdName=guojianrong, createdTime=Thu Aug 31 11:57:00 CST 2017, time=2017-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1595658, encodeId=7b5c159565836, content=<a href='/topic/show?id=ec7c5485b0' target=_blank style='color:#2F92EE;'>#CT表现#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5485, encryptionId=ec7c5485b0, topicName=CT表现)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=97b318291922, createdName=smallant2008, createdTime=Thu Aug 31 11:57:00 CST 2017, time=2017-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=238619, encodeId=c7bb238619e4, content=好好学习.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Wed Aug 30 09:38:10 CST 2017, time=2017-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=238438, encodeId=101e23843836, content=好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Tue Aug 29 21:26:15 CST 2017, time=2017-08-29, status=1, ipAttribution=)]
    2017-08-30 shaosai

    好好学习.谢谢分享!

    0

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    2017-08-29 thlabcde

    好东西学习了!

    0

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