Am J Gastroenterol:美国结直肠癌筛查指南

2017-06-08 zhangfan MedSci原创

近日代表美国胃肠病学会、美国胃肠病学会、美国胃肠内镜学会的大肠癌社会协会(MSTF)公布了最新的美国结直肠癌(CRC)筛查建议

近日代表美国胃肠病学会、美国胃肠病学会、美国胃肠内镜学会的大肠癌社会协会(MSTF)公布了最新的美国结直肠癌(CRC)筛查建议。

根据性能,成本和实际情况,CRC筛查分为3级。第1级为每10年一次结肠镜检查和每年的粪便免疫化学试验(FIT)。结肠镜检查和FIT是各种筛查的基石,结肠镜检查为第一选择而FIT可减少患者接受结肠镜检查的次数;第2级包括每5年进行结肠CT,每3年进行粪便排泄物DNA测试和每5-10年的可屈性乙状结肠镜检查,上述检测是适当的筛选试验,但相比于第1级检查有各自的缺点;由于有限的证据和目前存在的使用障碍,每5年进行胶囊结肠镜检查为第3级测试。不建议SEPT9血清检测作为常规的结肠癌筛选手段。

平均风险人群的起始筛查年龄为50岁,非裔美国人在45年开始筛查。50岁以下CRC患者比例目前成上升趋势,故疑似大肠出血的年轻人应进行全面的诊断。对于持续结肠镜筛查阴性至75岁的老年人可考虑终止筛查,对于从未进行过筛查的老人应根据年龄和合并症考虑筛查至85岁。对于有家族大肠癌史、<60岁的晚期腺瘤一级亲属和2名肿瘤的一级亲属患者的人群,推荐在平均风险年龄或40岁前甚至更早,每5年进行结肠镜检查;对于>60岁的结肠癌或晚期腺癌一级亲属的人群,其具有结肠癌的平均风险,推荐初始检查年龄为40岁。

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    2018-03-13 许安
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    2017-06-09 luominglian113

    学习了,谢谢分享

    0

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    2017-06-08 清风拂面

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