The Lancet Psychiatry:社交焦虑障碍治疗荟萃分析

2014-10-28 MedSci MedSci原创

http://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(14)70329-3/abstract

社交焦虑障碍是一种对任何社交或公开场合感到强烈恐惧或忧虑的慢性、持续性精神疾病,可引起神经系统的器质性损害,目前可通过药物、心理和自我干预等多种措施进行治疗。本研究即在于比较上述干预措施,以便确定有效的成人社交焦虑症急性治疗措施。 研究方法: 研究人员针对成年社交焦虑症患者的干预措施,进行了系统性回顾和网络荟萃分析,收集自1988年至2013年9月13日的发布及未发布的资料。研究人员对干预措施进行聚类分析和独立分析。临床结局证实社交焦虑障碍干预措施的有效性,并以相对于候选参考的标准平均差(SMDs)进行描述。该研究在PROSPERO进行注册,注册号为CRD42012003146。 研究结果: 本研究中,研究人员共收集101项临床试验的资料(13164名志愿者),包括41项干预措施或对照措施(17个类别)。与候选参考相比,具有更好的临床结局的药物类干预措施为单胺氧化酶抑制剂(SMD −1·01,95%置信区间−1.56至−0.45)、苯二氮卓类(−0.96, −1.56至−0.36)、选择性5-强色胺重摄取抑制剂和5-羟色胺-去甲肾上腺素重摄取抑制剂(SSRIs和SNRIs;−0.91,

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    2014-10-30 fengyi818
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    2014-10-29 218.249.94.9

    自我管理自我鼓励还是蛮重要的

    0

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    2015-07-23 howi

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