GUT:全谷物饮食会影响你的肠道微生物吗?

2018-03-12 海北 MedSci原创

最近,来自丹麦技术大学的研究人员进行了一项研究,调查全谷类食物是否改变肠道微生物群,胰岛素敏感性,以及代谢健康和肠道功能的生物标志物。

最近,来自丹麦技术大学的研究人员进行了一项研究,调查全谷类食物是否改变肠道微生物群,胰岛素敏感性,以及代谢健康和肠道功能的生物标志物。

研究人员招募了60名处于代谢综合征风险发展中的丹麦成人,其被纳入一项随机交叉试验,进行两个8周的饮食干预期,饮食包括全谷物饮食和精制谷物饮食。两个8周之间存在时间间隔为≥6周的清除期。研究人员对肠道微生物组成的干预,胰岛素敏感性,以及葡萄糖和脂质代谢,消化道功能,炎症标志物,人体测量学和尿代谢组学进行了评估。

50名参与者完成了两个阶段,在全谷物和精制谷物期间分别完成了全谷物摄入量179±50g /天和13±10g /天。依从性被血浆烷基间苯二酚的差异所证实(p <0.0001)。

与精制谷物相比,全谷物不会显着改变葡萄糖稳态,并且不会引起粪便微生物组的重大变化。此外,呼吸氢水平,血浆短链脂肪酸,肠道完整性,以及肠道转运时间也都不受影响。然而,与精制谷物相比,全谷物饮食能够降低体重(p <0.0001),减少血清炎症标志物,白细胞介素(IL)-6(p = 0.009),和C反应蛋白(p = 0.003)。体重减少与能量摄入减少一致,IL-6减少与全谷物消耗量相关,特别是摄入黑麦时。

与精制谷物相比,全谷物饮食不改变胰岛素敏感性和肠道微生物组,但能够降低体重和全身低度炎症。


原始出处:

Henrik Munch Roager et al. Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial. GUT; DOI: http://dx.doi.org/10.1136/gutjnl-2017-314786


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    2018-06-08 licz0435
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    2018-03-13 cscdliu

    学习了.谢谢

    0

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    2018-03-13 yfjms

    学习

    0

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    2018-03-13 秀红

    学习了

    0

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    2018-03-12 bluemooning

    我们都会有.我的.我的人都有一个人的

    0

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