J Periodontol:正接受化疗的乳腺癌患者也可接受牙周非手术治疗

2016-10-27 MedSci MedSci原创

虽然多种疾病同时存在时往往会选择最危及生命的疾病优先治疗,如癌症,但是也应关注预防及改善口腔其他并发症,这些并发症可能是因癌症所致或癌症治疗所致。本研究旨在通过临床监测和C反应蛋白(CRP)水平来对比了健康人和正接受化疗的乳腺癌患者牙周治疗的结果。研究共纳入35名参与者,将其分为两组:牙周炎患者组(P,n = 18)和伴有牙周炎的乳腺癌患者组(CAN/P,n = 17)。基线和非手术牙周治疗(NS

虽然多种疾病同时存在时往往会选择最危及生命的疾病优先治疗,如癌症,但是也应关注预防及改善口腔其他并发症,这些并发症可能是因癌症所致或癌症治疗所致。本研究旨在通过临床监测和C反应蛋白(CRP)水平来对比了健康人和正接受化疗的乳腺癌患者牙周治疗的结果。

研究共纳入35名参与者,将其分为两组:牙周炎患者组(P,n = 18)和伴有牙周炎的乳腺癌患者组(CAN/P,n = 17)。基线和非手术牙周治疗(NSPT)后的45天、90天及180天时评估以下临床参数:1)探测深度(PD);2)临床附着水平(CAL);3)斑块指数(PI);4)牙龈指数(GI);5)CRP;和6)全血细胞计数。临床参数和血清C反应蛋白水平进行统计学分析。

结果,与基线时期相比,P 组和CAN/P组患者NSPT治疗45天、90天和180天后,PD显著降低(P<0.05)。P组治疗后CAL获得明显,治疗45天、90天和180天后两组患者的PI和GI显著降低(P<0.05)。NSPT治疗后180天,与P组相比,CAN/P组剩余牙周袋的数目较高(P<0.05)(分别为46.48±26.80和7.58±7.40)。与基线时期相比,NSPT治疗后45天和180天P组患者的CRP水平显著降低(P<0.05),而CAN/P组则未见明显减少。

该研究发现,正接受化疗的乳腺恶性肿瘤患者对牙周非手术治疗反应较好,虽然效果较非癌症患者的牙周炎患者差,这或需额外的或辅助牙周治疗。

原始出处:

Vargas-Villafuerte KR, et al., Preliminary Results of Non-Surgical Periodontal Treatment in Patients With Breast Cancer Undergoing Chemotherapy. J Periodontol. 2016 Nov;87(11):1268-1277.

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    2016-12-17 爆笑小医
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time=2016-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151645, encodeId=41d2151645e2, content=不去做不去想。, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Oct 28 07:32:05 CST 2016, time=2016-10-28, status=1, ipAttribution=)]
    2016-11-08 ylzr123

    正接受化疗的乳腺恶性肿瘤患者对牙周非手术治疗反应较好,虽然效果较非癌症患者的牙周炎患者差,这或需额外的或辅助牙周治疗。

    0

  4. 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topicId=null, topicList=[TopicDto(id=54454, encryptionId=e86454454ea, topicName=手术治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=920c231, createdName=lixiaol, createdTime=Sat Oct 29 12:05:00 CST 2016, time=2016-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416572, encodeId=dacf14165e297, content=<a href='/topic/show?id=7d7e9944e99' target=_blank style='color:#2F92EE;'>#非手术治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99447, encryptionId=7d7e9944e99, topicName=非手术治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=73fb3217487, createdName=chentianping, createdTime=Sat Oct 29 12:05:00 CST 2016, time=2016-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450488, encodeId=1e471450488fa, content=<a href='/topic/show?id=f0476e49582' target=_blank 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time=2016-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151645, encodeId=41d2151645e2, content=不去做不去想。, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Oct 28 07:32:05 CST 2016, time=2016-10-28, status=1, ipAttribution=)]
  5. 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  6. 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time=2016-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151645, encodeId=41d2151645e2, content=不去做不去想。, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Oct 28 07:32:05 CST 2016, time=2016-10-28, status=1, ipAttribution=)]
  7. 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createdBy=395f25, createdName=爆笑小医, createdTime=Sat Dec 17 00:05:00 CST 2016, time=2016-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154349, encodeId=060e1543495e, content=正接受化疗的乳腺恶性肿瘤患者对牙周非手术治疗反应较好,虽然效果较非癌症患者的牙周炎患者差,这或需额外的或辅助牙周治疗。, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Nov 08 14:53:04 CST 2016, time=2016-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290591, encodeId=bfce1290591ee, content=<a href='/topic/show?id=e86454454ea' target=_blank style='color:#2F92EE;'>#手术治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, 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style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Sat Oct 29 12:05:00 CST 2016, time=2016-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571010, encodeId=0b4415e10100e, content=<a href='/topic/show?id=f42823e48d7' target=_blank style='color:#2F92EE;'>#乳腺癌患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23748, encryptionId=f42823e48d7, topicName=乳腺癌患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=37bc15724202, createdName=hanhaisha2013, createdTime=Sat Oct 29 12:05:00 CST 2016, time=2016-10-29, status=1, ipAttribution=), 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  8. 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time=2016-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151645, encodeId=41d2151645e2, content=不去做不去想。, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Oct 28 07:32:05 CST 2016, time=2016-10-28, status=1, ipAttribution=)]
    2016-10-28 zhixue

    在国内,不会有人这么重视牙周病的,尤其癌症患者,更不会,牙周病大不了就是掉牙,没人知道它和全身疾病之间的关系!以后随着科普普及,可能会好一些!

    0

  9. 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createdBy=395f25, createdName=爆笑小医, createdTime=Sat Dec 17 00:05:00 CST 2016, time=2016-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154349, encodeId=060e1543495e, content=正接受化疗的乳腺恶性肿瘤患者对牙周非手术治疗反应较好,虽然效果较非癌症患者的牙周炎患者差,这或需额外的或辅助牙周治疗。, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Nov 08 14:53:04 CST 2016, time=2016-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290591, encodeId=bfce1290591ee, content=<a href='/topic/show?id=e86454454ea' target=_blank style='color:#2F92EE;'>#手术治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, 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time=2016-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151645, encodeId=41d2151645e2, content=不去做不去想。, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Oct 28 07:32:05 CST 2016, time=2016-10-28, status=1, ipAttribution=)]
    2016-10-28 doctorJiangchao

    虽然有这个结果 但是临床上谁去冒险了

    0

  10. 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createdBy=395f25, createdName=爆笑小医, createdTime=Sat Dec 17 00:05:00 CST 2016, time=2016-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154349, encodeId=060e1543495e, content=正接受化疗的乳腺恶性肿瘤患者对牙周非手术治疗反应较好,虽然效果较非癌症患者的牙周炎患者差,这或需额外的或辅助牙周治疗。, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Tue Nov 08 14:53:04 CST 2016, time=2016-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290591, encodeId=bfce1290591ee, content=<a href='/topic/show?id=e86454454ea' target=_blank style='color:#2F92EE;'>#手术治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54454, encryptionId=e86454454ea, topicName=手术治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=920c231, createdName=lixiaol, createdTime=Sat Oct 29 12:05:00 CST 2016, time=2016-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416572, encodeId=dacf14165e297, content=<a href='/topic/show?id=7d7e9944e99' target=_blank style='color:#2F92EE;'>#非手术治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99447, encryptionId=7d7e9944e99, topicName=非手术治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=73fb3217487, createdName=chentianping, createdTime=Sat Oct 29 12:05:00 CST 2016, time=2016-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450488, encodeId=1e471450488fa, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Sat Oct 29 12:05:00 CST 2016, time=2016-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571010, encodeId=0b4415e10100e, content=<a href='/topic/show?id=f42823e48d7' target=_blank style='color:#2F92EE;'>#乳腺癌患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23748, encryptionId=f42823e48d7, topicName=乳腺癌患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=37bc15724202, createdName=hanhaisha2013, createdTime=Sat Oct 29 12:05:00 CST 2016, time=2016-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151758, encodeId=3009151e58ed, content=在国内,不会有人这么重视牙周病的,尤其癌症患者,更不会,牙周病大不了就是掉牙,没人知道它和全身疾病之间的关系!以后随着科普普及,可能会好一些!, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25101619573, createdName=zhixue, createdTime=Fri Oct 28 18:29:31 CST 2016, time=2016-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151650, encodeId=239415165042, content=虽然有这个结果 但是临床上谁去冒险了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Oct 28 07:56:21 CST 2016, time=2016-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151645, encodeId=41d2151645e2, content=不去做不去想。, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Oct 28 07:32:05 CST 2016, time=2016-10-28, status=1, ipAttribution=)]
    2016-10-28 jyzxjiangqin

    不去做不去想。

    0

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