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Int J Cardiol：妊娠期肝内胆汁瘀积症使女性心血管疾病风险增加

2015-04-21 Mechront 译 MedSci原创

胆汁瘀积ICP心血管QT间期
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胆汁酸可以通过改变心肌细胞收缩性从而诱发心律失常，而妊娠期肝内胆汁瘀积症（ICP）的诊断标准便是孕妇总胆酸含量的增高。Kirbas O等人进行了一项病例对照试验，通过对比ICP、非ICP孕妇简单标准心电图(ECG)测量的QT间期离散度，评估ICP与心室复极化间究竟有无关系。该研究共纳入75名ICP孕妇和35名健康、没有妊娠期并发症的孕妇（对照）。通过Hodges公式对研究对象的心率进行校正。记录心

准妈妈携带乙肝病毒 要缩短分娩时间

胆汁酸可以通过改变心肌细胞收缩性从而诱发心律失常，而妊娠期肝内胆汁瘀积症（ICP）的诊断标准便是孕妇总胆酸含量的增高。Kirbas O等人进行了一项病例对照试验，通过对比ICP、非ICP孕妇简单标准心电图(ECG)测量的QT间期离散度，评估ICP与心室复极化间究竟有无关系。

该研究共纳入75名ICP孕妇和35名健康、没有妊娠期并发症的孕妇（对照）。通过Hodges公式对研究对象的心率进行校正。记录心电图QT间期、QT间期离散度(QT-disp)参数等。

研究结果显示，最大QT间期值在重度ICP患者中最高，不仅高于对照组(p<0.001)，同时也高于轻度ICP(p=0.01)。而该值在轻度ICP和对照组中相似。同时数据分析表明，ICP组（重度+轻度）QT-disp值明显高于对照组，而在ICP内部对比发现，重度ICP该值明显高于轻度ICP孕妇。

研究结果表明，妊娠期肝内胆汁瘀积症（ICP）会导致女性心血管疾病风险增加。同时研究数据清楚地表明，ICP孕妇相比正常孕妇，其QT-disp值显著改变。研究者提出，可以使用标准心电图(ECG)对高危女性进行筛查，以利于对既往有ICP病史的女性进行更好的生活方式咨询、以后的密切检测和管理等。

原始出处：

Kirbas O, Biberoglu EH, Kirbas A, Daglar K, Kurmus O, Danisman N, Biberoglu K: Evaluation of ventricular repolarization in pregnant women with intrahepatic cholestasis. International journal of cardiology 2015, 189:25-29.

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    2015-12-17 ms5880526374914242

    #胆汁瘀积#

    0

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    2015-05-11 仁者大医

    #Cardiol#

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    2015-04-23 wjcjjian

    #妊娠期#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1809421, encodeId=ecae18094212b, content=<a href='/topic/show?id=6830834839f' target=_blank style='color:#2F92EE;'>#胆汁瘀积#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83483, encryptionId=6830834839f, topicName=胆汁瘀积)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqySEUYKeYDjXJMYMrtscBNkpAnLfQZgDcdkEratcJPqS7ARJOXqllZQhCSFicErlBFbIywuoiaP0LQ/132, createdBy=012d2500132, createdName=ms5880526374914242, createdTime=Thu Dec 17 13:52:00 CST 2015, time=2015-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1781682, encodeId=8f861e81682d5, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Mon May 11 18:52:00 CST 2015, time=2015-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250957, encodeId=f4bf125095e7c, content=<a href='/topic/show?id=90494486837' target=_blank style='color:#2F92EE;'>#妊娠期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44868, encryptionId=90494486837, topicName=妊娠期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1472959, encodeId=20a214e2959fd, content=<a href='/topic/show?id=862be0746bc' target=_blank style='color:#2F92EE;'>#疾病风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70746, encryptionId=862be0746bc, topicName=疾病风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c757221906, createdName=花花1368, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497881, encodeId=718e149e88185, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579148, encodeId=29e215e91484f, content=<a href='/topic/show?id=372b834e673' target=_blank style='color:#2F92EE;'>#胆汁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83476, encryptionId=372b834e673, topicName=胆汁)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a0616505872, createdName=108807375_62823132, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21665, encodeId=c2c621665c4, content=学习了，我爱人就有过。, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=121e1622385, createdName=chenhui888, createdTime=Wed Apr 22 09:29:00 CST 2015, time=2015-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21650, encodeId=24f32165007, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=cspcsp, createdTime=Wed Apr 22 00:31:00 CST 2015, time=2015-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21649, encodeId=7214216499b, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=cspcsp, createdTime=Wed Apr 22 00:30:00 CST 2015, time=2015-04-22, status=1, ipAttribution=)]
    2015-04-23 花花1368

    #疾病风险#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1809421, encodeId=ecae18094212b, content=<a href='/topic/show?id=6830834839f' target=_blank style='color:#2F92EE;'>#胆汁瘀积#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83483, encryptionId=6830834839f, topicName=胆汁瘀积)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqySEUYKeYDjXJMYMrtscBNkpAnLfQZgDcdkEratcJPqS7ARJOXqllZQhCSFicErlBFbIywuoiaP0LQ/132, createdBy=012d2500132, createdName=ms5880526374914242, createdTime=Thu Dec 17 13:52:00 CST 2015, time=2015-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1781682, encodeId=8f861e81682d5, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Mon May 11 18:52:00 CST 2015, time=2015-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250957, encodeId=f4bf125095e7c, content=<a href='/topic/show?id=90494486837' target=_blank style='color:#2F92EE;'>#妊娠期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44868, encryptionId=90494486837, topicName=妊娠期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1472959, encodeId=20a214e2959fd, content=<a href='/topic/show?id=862be0746bc' target=_blank style='color:#2F92EE;'>#疾病风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70746, encryptionId=862be0746bc, topicName=疾病风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c757221906, createdName=花花1368, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497881, encodeId=718e149e88185, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579148, encodeId=29e215e91484f, content=<a href='/topic/show?id=372b834e673' target=_blank style='color:#2F92EE;'>#胆汁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83476, encryptionId=372b834e673, topicName=胆汁)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a0616505872, createdName=108807375_62823132, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21665, encodeId=c2c621665c4, content=学习了，我爱人就有过。, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=121e1622385, createdName=chenhui888, createdTime=Wed Apr 22 09:29:00 CST 2015, time=2015-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21650, encodeId=24f32165007, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=cspcsp, createdTime=Wed Apr 22 00:31:00 CST 2015, time=2015-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21649, encodeId=7214216499b, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=cspcsp, createdTime=Wed Apr 22 00:30:00 CST 2015, time=2015-04-22, status=1, ipAttribution=)]
    2015-04-23 andy2090

    #血管疾病#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1809421, encodeId=ecae18094212b, content=<a href='/topic/show?id=6830834839f' target=_blank style='color:#2F92EE;'>#胆汁瘀积#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83483, encryptionId=6830834839f, topicName=胆汁瘀积)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqySEUYKeYDjXJMYMrtscBNkpAnLfQZgDcdkEratcJPqS7ARJOXqllZQhCSFicErlBFbIywuoiaP0LQ/132, createdBy=012d2500132, createdName=ms5880526374914242, createdTime=Thu Dec 17 13:52:00 CST 2015, time=2015-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1781682, encodeId=8f861e81682d5, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Mon May 11 18:52:00 CST 2015, time=2015-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250957, encodeId=f4bf125095e7c, content=<a href='/topic/show?id=90494486837' target=_blank style='color:#2F92EE;'>#妊娠期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44868, encryptionId=90494486837, topicName=妊娠期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1472959, encodeId=20a214e2959fd, content=<a href='/topic/show?id=862be0746bc' target=_blank style='color:#2F92EE;'>#疾病风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70746, encryptionId=862be0746bc, topicName=疾病风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c757221906, createdName=花花1368, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497881, encodeId=718e149e88185, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579148, encodeId=29e215e91484f, content=<a href='/topic/show?id=372b834e673' target=_blank style='color:#2F92EE;'>#胆汁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83476, encryptionId=372b834e673, topicName=胆汁)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a0616505872, createdName=108807375_62823132, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21665, encodeId=c2c621665c4, content=学习了，我爱人就有过。, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=121e1622385, createdName=chenhui888, createdTime=Wed Apr 22 09:29:00 CST 2015, time=2015-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21650, encodeId=24f32165007, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=cspcsp, createdTime=Wed Apr 22 00:31:00 CST 2015, time=2015-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21649, encodeId=7214216499b, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=cspcsp, createdTime=Wed Apr 22 00:30:00 CST 2015, time=2015-04-22, status=1, ipAttribution=)]
    2015-04-23 108807375_62823132

    #胆汁#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1809421, encodeId=ecae18094212b, content=<a href='/topic/show?id=6830834839f' target=_blank style='color:#2F92EE;'>#胆汁瘀积#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83483, encryptionId=6830834839f, topicName=胆汁瘀积)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqySEUYKeYDjXJMYMrtscBNkpAnLfQZgDcdkEratcJPqS7ARJOXqllZQhCSFicErlBFbIywuoiaP0LQ/132, createdBy=012d2500132, createdName=ms5880526374914242, createdTime=Thu Dec 17 13:52:00 CST 2015, time=2015-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1781682, encodeId=8f861e81682d5, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Mon May 11 18:52:00 CST 2015, time=2015-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250957, encodeId=f4bf125095e7c, content=<a href='/topic/show?id=90494486837' target=_blank style='color:#2F92EE;'>#妊娠期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44868, encryptionId=90494486837, topicName=妊娠期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1472959, encodeId=20a214e2959fd, content=<a href='/topic/show?id=862be0746bc' target=_blank style='color:#2F92EE;'>#疾病风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70746, encryptionId=862be0746bc, topicName=疾病风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c757221906, createdName=花花1368, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497881, encodeId=718e149e88185, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579148, encodeId=29e215e91484f, content=<a href='/topic/show?id=372b834e673' target=_blank style='color:#2F92EE;'>#胆汁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83476, encryptionId=372b834e673, topicName=胆汁)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a0616505872, createdName=108807375_62823132, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21665, encodeId=c2c621665c4, content=学习了，我爱人就有过。, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=121e1622385, createdName=chenhui888, createdTime=Wed Apr 22 09:29:00 CST 2015, time=2015-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21650, encodeId=24f32165007, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=cspcsp, createdTime=Wed Apr 22 00:31:00 CST 2015, time=2015-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21649, encodeId=7214216499b, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=cspcsp, createdTime=Wed Apr 22 00:30:00 CST 2015, time=2015-04-22, status=1, ipAttribution=)]
    2015-04-22 chenhui888

    学习了，我爱人就有过。

    0

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    2015-04-22 cspcsp

    有趣

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1809421, encodeId=ecae18094212b, content=<a href='/topic/show?id=6830834839f' target=_blank style='color:#2F92EE;'>#胆汁瘀积#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83483, encryptionId=6830834839f, topicName=胆汁瘀积)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqySEUYKeYDjXJMYMrtscBNkpAnLfQZgDcdkEratcJPqS7ARJOXqllZQhCSFicErlBFbIywuoiaP0LQ/132, createdBy=012d2500132, createdName=ms5880526374914242, createdTime=Thu Dec 17 13:52:00 CST 2015, time=2015-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1781682, encodeId=8f861e81682d5, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Mon May 11 18:52:00 CST 2015, time=2015-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250957, encodeId=f4bf125095e7c, content=<a href='/topic/show?id=90494486837' target=_blank style='color:#2F92EE;'>#妊娠期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44868, encryptionId=90494486837, topicName=妊娠期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1472959, encodeId=20a214e2959fd, content=<a href='/topic/show?id=862be0746bc' target=_blank style='color:#2F92EE;'>#疾病风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70746, encryptionId=862be0746bc, topicName=疾病风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3c757221906, createdName=花花1368, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1497881, encodeId=718e149e88185, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579148, encodeId=29e215e91484f, content=<a href='/topic/show?id=372b834e673' target=_blank style='color:#2F92EE;'>#胆汁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83476, encryptionId=372b834e673, topicName=胆汁)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a0616505872, createdName=108807375_62823132, createdTime=Thu Apr 23 13:52:00 CST 2015, time=2015-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21665, encodeId=c2c621665c4, content=学习了，我爱人就有过。, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=121e1622385, createdName=chenhui888, createdTime=Wed Apr 22 09:29:00 CST 2015, time=2015-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21650, encodeId=24f32165007, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=cspcsp, createdTime=Wed Apr 22 00:31:00 CST 2015, time=2015-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=21649, encodeId=7214216499b, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=cspcsp, createdTime=Wed Apr 22 00:30:00 CST 2015, time=2015-04-22, status=1, ipAttribution=)]
    2015-04-22 cspcsp

    有用

    0