Lancet:脑囊虫病致儿童死亡-案例报道

2016-05-09 Mechront 译 MedSci原创

患者男,10岁,因1小时前全面性强直阵挛发作就诊。既往癫痫、头痛伴发热史3年。使用苯妥英钠(5mg/kg bid)治疗。就诊急诊时,患者已经心脏骤停(呼吸 5次/分,心率40次/分,收缩压50 mmHg,脉搏微弱,毛细血管再充盈 >15秒)。患者无意识(GCS: 3/15),双侧瞳孔散大无反应。心肺复苏等一系列抢救后,宣布患者死亡。尸检:大脑冠状切面显示双侧脑室腔塌陷,脑皮质广泛水肿,皮质下

患者男,10岁,因1小时前全面性强直阵挛发作就诊。

既往癫痫、头痛伴发热史3年。使用苯妥英钠(5mg/kg bid)治疗。

就诊急诊时,患者已经心脏骤停(呼吸 5次/分,心率40次/分,收缩压50 mmHg,脉搏微弱,毛细血管再充盈 >15秒)。患者无意识(GCS: 3/15),双侧瞳孔散大无反应。

心肺复苏等一系列抢救后,宣布患者死亡。

尸检:大脑冠状切面显示双侧脑室腔塌陷,脑皮质广泛水肿,皮质下可见大小不同的众多脑实质囊肿,一些可见幼虫。



镜检:囊肿内可见幼虫和分解物,以及间质沉积、纤维化、增生和坏死。



脑囊虫病是由寄生虫(猪绦虫为主)所传染的一种顽固性颅脑内疾病。该病约占囊虫病的80%以上。是由于口服了猪肉绦虫虫卵,发育成囊尾蚴,经消化道穿出肠壁进入肠系膜小静脉,再经体循环而到达脑膜、脑实质以及脑室内。患此病后脑组织及大脑中枢损伤严重,头疼、浑身无力、肢体运动障碍,最严重的是继发癫痫,视物不清,甚至失明,再甚者就诸如本案例中的死亡。

原始出处:

Nelly Gonzalez,Maria Guadalupe Trevino,et al.Cysticercal encephalitis.The Lancet.DOI: http://dx.doi.org/10.1016/S0140-6736(13)60691-1

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    2017-01-17 howi
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    2016-08-29 ylzr123

    深入学习,好文值得点赞!

    0

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    2016-06-15 早茶月光

    有点可怕!一定要注意宝宝们的饮食了

    0

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    2016-05-16 lecoo

    囊虫病在牧区比较常见。

    0

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    2016-05-15 Lisa971

    这种疾病,早期发现,能有效挽救没?

    0

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    2016-05-14 吴教授

    有密集恐惧症

    0

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    2016-05-10 1dd8a7c5m95(暂无匿称)

    值得阅读,学习!

    0

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    2016-05-09 jaysppr

    这关这种病例报道

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