子宫内膜再生术为不孕者带来“再生宝宝”,有望三年后产业化

2017-05-22 郑生竹、董瑞丰 新华社

严重子宫内膜损伤导致的重度子宫腔粘连曾被认为是导致不孕不育的绝症。记者从中科院遗传发育所再生医学中心获悉,该中心戴建武研究员团队联合南京鼓楼医院研发的子宫内膜再生术,自2013年开展临床研究以来,已取得重要突破,先后有13名宫腔粘连患者通过该项技术生下“再生宝宝”。“子宫内膜损伤后会出现明显的瘢痕化,供血不足,导致受精卵无法着床发育,就像土地变成了水泥地而长不出植物一样。”据南京鼓楼医院副院长、妇

严重子宫内膜损伤导致的重度子宫腔粘连曾被认为是导致不孕不育的绝症。记者从中科院遗传发育所再生医学中心获悉,该中心戴建武研究员团队联合南京鼓楼医院研发的子宫内膜再生术,自2013年开展临床研究以来,已取得重要突破,先后有13名宫腔粘连患者通过该项技术生下“再生宝宝”。

“子宫内膜损伤后会出现明显的瘢痕化,供血不足,导致受精卵无法着床发育,就像土地变成了水泥地而长不出植物一样。”据南京鼓楼医院副院长、妇产科主任胡娅莉介绍,随着宫腔操作的增加而导致的宫腔粘连发生率升高,已成为女性继发不孕的重要病因。最新统计数据显示,我国不孕人口数已超过5000万人,因宫腔粘连而导致的不孕患者占了很大一部分。

来自南京的周女士在2012年因胎儿出现心脏病问题做过引产,导致其出现宫腔粘连而不孕不育。之后曾做过一次宫腔镜粘连分离术,效果不太好。2014年她在鼓楼医院做了宫腔内膜再生术后,顺利怀孕和分娩,现在她的小孩已有8个多月大。“小孩70多厘米,19斤多,各项指标都很正常。”张女士说。

干细胞的作用是分泌很多营养成分,就像用于土壤改良的有机质,干细胞放在支架材料上后,可以吸引血管长到支架上来,然后细胞被牵引过来,形成新的内膜,或者让内膜增厚。”据戴建武介绍,目前宫腔镜粘连分离术虽是治疗宫腔粘连的经典方法,但预防粘连复发效果不佳。子宫内膜再生技术创新之处是利用支架材料帮助干细胞定植、分化,从而实现血管、组织的再生,修复瘢痕化的子宫内膜,为受精卵提供着床、发育的环境。

据介绍,该项技术在很多细节上都有创新,获得多项专利。因此项技术是基于生物材料和干细胞而属于医疗器械范畴,未来可通过医疗器械企业来转化这项科技成果,有望在三四年后实现产业化。

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    2017-12-29 cnxcy
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    2017-05-23 sillywu

    学术到实践的典型啊,很有意义,真科研

    0

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    2017-05-23 飛歌

    学习了很有用

    0

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    2017-05-23 jaysppr

    感谢梅斯平台的分享!

    0

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