肿瘤科

订阅

MedSci主页 / 所有栏目 / 肿瘤科

Cancer Cell：日本发现辐射后白血病的致病基因

2013-09-12 佚名 新华网

核辐射白血病基因
关注

日本研究人员一项最新研究发现，某个基因与遭受辐射很长时间后才会发病的“迟发性”白血病有关。这将有助于对遭受辐射者进行健康管理，并对白血病进行早期预防、发现和治疗。【原文下载】 在遭受核辐射和在放射线治疗中遭受大量辐射后，有些人经过很长时间才会出现白血病和骨髓增生异常综合征（MDS）。广岛和长崎原子弹爆炸亲历者中就有很多这样的患者。广岛大学教授稻叶俊哉等人发现，很多患者的7号染色体异常，并


日本研究人员一项最新研究发现，某个基因与遭受辐射很长时间后才会发病的“迟发性”白血病有关。这将有助于对遭受辐射者进行健康管理，并对白血病进行早期预防、发现和治疗。【原文下载】

在遭受核辐射和在放射线治疗中遭受大量辐射后，有些人经过很长时间才会出现白血病和骨髓增生异常综合征（MDS）。广岛和长崎原子弹爆炸亲历者中就有很多这样的患者。广岛大学教授稻叶俊哉等人发现，很多患者的7号染色体异常，并锁定7号染色体上负责调整细胞分裂的一对“Samd9L”基因可能是致病原因。

研究人员通过基因操作获得这种基因异常的实验鼠，并与正常实验鼠进行对比研究。结果发现，健康的实验鼠在出生25个月后，因白血病和MDS而死亡的比率只有约7％，而缺乏一个“Samd9L”基因和缺乏一对该基因的实验鼠，这一数字则分别是53％和60％。

不过，这些缺乏一个或一对“Samd9L”基因的实验鼠在一年之内都没有出现死亡，而且也几乎未患其他恶性肿瘤。稻叶俊哉说，虽然该基因比其他基因致癌的能力弱，但却能带来长期影响。

这项研究成果已发表在美国《癌细胞》杂志网络版上。

原文下载

Akiko Nagamachi, Hirotaka Matsui, Hiroya Asou, Yuko Ozaki, Daisuke Aki, Akinori Kanai, Keiyo Takubo, Toshio Suda, Takuro Nakamura, Linda Wolff, Hiroaki Honda, Toshiya Inaba. Haploinsufficiency of SAMD9L, an Endosome Fusion Facilitator, auses Myeloid Malignancies in Mice Mimicking Human Diseases with Monosomy 7.CANCER CELL 2013 September 9.


    

版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1780604, encodeId=b4071e806049c, content=<a href='/topic/show?id=517a4016ac' target=_blank style='color:#2F92EE;'>#cancer cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4016, encryptionId=517a4016ac, topicName=cancer cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96f62500201, createdName=12498e67m28暂无昵称, createdTime=Sat Sep 14 01:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1868681, encodeId=6fe818686818b, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Tue Jan 14 04:05:00 CST 2014, time=2014-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958920, encodeId=51c219589202e, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Thu Oct 31 23:05:00 CST 2013, time=2013-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1294136, encodeId=1b19129413669, content=<a href='/topic/show?id=ca6e592189b' target=_blank style='color:#2F92EE;'>#日本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59218, encryptionId=ca6e592189b, topicName=日本)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1349291, encodeId=86e41349291f9, content=<a href='/topic/show?id=838593e35b2' target=_blank style='color:#2F92EE;'>#辐射#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93735, encryptionId=838593e35b2, topicName=辐射)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488490, encodeId=e7d21488490eb, content=<a href='/topic/show?id=b569864e51e' target=_blank style='color:#2F92EE;'>#致病基因#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86475, encryptionId=b569864e51e, topicName=致病基因)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6d1a8427162, createdName=wfang548, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=)]
    2013-09-14 12498e67m28暂无昵称

    #cancer cell#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1780604, encodeId=b4071e806049c, content=<a href='/topic/show?id=517a4016ac' target=_blank style='color:#2F92EE;'>#cancer cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4016, encryptionId=517a4016ac, topicName=cancer cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96f62500201, createdName=12498e67m28暂无昵称, createdTime=Sat Sep 14 01:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1868681, encodeId=6fe818686818b, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Tue Jan 14 04:05:00 CST 2014, time=2014-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958920, encodeId=51c219589202e, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Thu Oct 31 23:05:00 CST 2013, time=2013-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1294136, encodeId=1b19129413669, content=<a href='/topic/show?id=ca6e592189b' target=_blank style='color:#2F92EE;'>#日本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59218, encryptionId=ca6e592189b, topicName=日本)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1349291, encodeId=86e41349291f9, content=<a href='/topic/show?id=838593e35b2' target=_blank style='color:#2F92EE;'>#辐射#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93735, encryptionId=838593e35b2, topicName=辐射)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488490, encodeId=e7d21488490eb, content=<a href='/topic/show?id=b569864e51e' target=_blank style='color:#2F92EE;'>#致病基因#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86475, encryptionId=b569864e51e, topicName=致病基因)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6d1a8427162, createdName=wfang548, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=)]
    2014-01-14 zhaozhouchifen

    #Cell#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1780604, encodeId=b4071e806049c, content=<a href='/topic/show?id=517a4016ac' target=_blank style='color:#2F92EE;'>#cancer cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4016, encryptionId=517a4016ac, topicName=cancer cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96f62500201, createdName=12498e67m28暂无昵称, createdTime=Sat Sep 14 01:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1868681, encodeId=6fe818686818b, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Tue Jan 14 04:05:00 CST 2014, time=2014-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958920, encodeId=51c219589202e, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Thu Oct 31 23:05:00 CST 2013, time=2013-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1294136, encodeId=1b19129413669, content=<a href='/topic/show?id=ca6e592189b' target=_blank style='color:#2F92EE;'>#日本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59218, encryptionId=ca6e592189b, topicName=日本)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1349291, encodeId=86e41349291f9, content=<a href='/topic/show?id=838593e35b2' target=_blank style='color:#2F92EE;'>#辐射#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93735, encryptionId=838593e35b2, topicName=辐射)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488490, encodeId=e7d21488490eb, content=<a href='/topic/show?id=b569864e51e' target=_blank style='color:#2F92EE;'>#致病基因#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86475, encryptionId=b569864e51e, topicName=致病基因)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6d1a8427162, createdName=wfang548, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=)]
    2013-10-31 维他命

    #CEL#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1780604, encodeId=b4071e806049c, content=<a href='/topic/show?id=517a4016ac' target=_blank style='color:#2F92EE;'>#cancer cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4016, encryptionId=517a4016ac, topicName=cancer cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96f62500201, createdName=12498e67m28暂无昵称, createdTime=Sat Sep 14 01:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1868681, encodeId=6fe818686818b, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Tue Jan 14 04:05:00 CST 2014, time=2014-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958920, encodeId=51c219589202e, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Thu Oct 31 23:05:00 CST 2013, time=2013-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1294136, encodeId=1b19129413669, content=<a href='/topic/show?id=ca6e592189b' target=_blank style='color:#2F92EE;'>#日本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59218, encryptionId=ca6e592189b, topicName=日本)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1349291, encodeId=86e41349291f9, content=<a href='/topic/show?id=838593e35b2' target=_blank style='color:#2F92EE;'>#辐射#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93735, encryptionId=838593e35b2, topicName=辐射)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488490, encodeId=e7d21488490eb, content=<a href='/topic/show?id=b569864e51e' target=_blank style='color:#2F92EE;'>#致病基因#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86475, encryptionId=b569864e51e, topicName=致病基因)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6d1a8427162, createdName=wfang548, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=)]
    2013-09-14 chentianping

    #日本#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1780604, encodeId=b4071e806049c, content=<a href='/topic/show?id=517a4016ac' target=_blank style='color:#2F92EE;'>#cancer cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4016, encryptionId=517a4016ac, topicName=cancer cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96f62500201, createdName=12498e67m28暂无昵称, createdTime=Sat Sep 14 01:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1868681, encodeId=6fe818686818b, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Tue Jan 14 04:05:00 CST 2014, time=2014-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958920, encodeId=51c219589202e, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Thu Oct 31 23:05:00 CST 2013, time=2013-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1294136, encodeId=1b19129413669, content=<a href='/topic/show?id=ca6e592189b' target=_blank style='color:#2F92EE;'>#日本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59218, encryptionId=ca6e592189b, topicName=日本)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1349291, encodeId=86e41349291f9, content=<a href='/topic/show?id=838593e35b2' target=_blank style='color:#2F92EE;'>#辐射#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93735, encryptionId=838593e35b2, topicName=辐射)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488490, encodeId=e7d21488490eb, content=<a href='/topic/show?id=b569864e51e' target=_blank style='color:#2F92EE;'>#致病基因#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86475, encryptionId=b569864e51e, topicName=致病基因)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6d1a8427162, createdName=wfang548, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=)]
    2013-09-14 jiyangfei

    #辐射#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1780604, encodeId=b4071e806049c, content=<a href='/topic/show?id=517a4016ac' target=_blank style='color:#2F92EE;'>#cancer cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4016, encryptionId=517a4016ac, topicName=cancer cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96f62500201, createdName=12498e67m28暂无昵称, createdTime=Sat Sep 14 01:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1868681, encodeId=6fe818686818b, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Tue Jan 14 04:05:00 CST 2014, time=2014-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958920, encodeId=51c219589202e, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Thu Oct 31 23:05:00 CST 2013, time=2013-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1294136, encodeId=1b19129413669, content=<a href='/topic/show?id=ca6e592189b' target=_blank style='color:#2F92EE;'>#日本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59218, encryptionId=ca6e592189b, topicName=日本)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1349291, encodeId=86e41349291f9, content=<a href='/topic/show?id=838593e35b2' target=_blank style='color:#2F92EE;'>#辐射#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93735, encryptionId=838593e35b2, topicName=辐射)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488490, encodeId=e7d21488490eb, content=<a href='/topic/show?id=b569864e51e' target=_blank style='color:#2F92EE;'>#致病基因#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86475, encryptionId=b569864e51e, topicName=致病基因)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6d1a8427162, createdName=wfang548, createdTime=Sat Sep 14 00:05:00 CST 2013, time=2013-09-14, status=1, ipAttribution=)]
    2013-09-14 wfang548

    #致病基因#

    0