Breast: 年龄是乳腺癌患者预后不良的独立危险因素

2011-09-22 MedSci原创 MedSci原创

 广州中山大学肿瘤中心学者的一项回顾性病例对照研究共纳入551 例年龄≤35 岁的乳腺癌患者(Ⅰ组),将36~50 岁的乳腺癌患者作为对照(Ⅱ组)。   研究结果显示,Ⅰ组患者无病生存(DFS)期、5年DFS率和总生存(OS)率均显著低于Ⅱ组,P 值分别为0.024、<0.001 和 0.024。多因素分析显示,年龄(≤35岁)是乳腺癌患者预后不

 广州中山大学肿瘤中心学者的一项回顾性病例对照研究共纳入551 例年龄≤35 岁的乳腺癌患者(Ⅰ组),将36~50 岁的乳腺癌患者作为对照(Ⅱ组)。

  研究结果显示,Ⅰ组患者无病生存(DFS)期、5年DFS率和总生存(OS)率均显著低于Ⅱ组,P 值分别为0.024、<0.001 和 0.024。多因素分析显示,年龄(≤35岁)是乳腺癌患者预后不良的独立危险因素。相关论文于8月13日在线发表于Breast。

    MedSci分析认为,这篇文章的研究着眼于DFS和年龄,而且观察到35岁作为年龄的重要分水岭,这是主要的创新之处。

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    2011-09-24 zhaojie88
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