JAIDS:HIV感染者新希望,抗逆转录病毒治疗

2014-10-17 佚名 生物谷

近日旧金山加州大学新临床研究显示,与那些不使用兴奋剂的感染艾滋病毒的人相比,341名使用冰毒和可卡因的感染艾滋病毒的人通过抗逆转录病毒的方法治疗初步见效。 “艾滋病患者用抗逆转录病毒疗法常常遇到困难,部分原因由于医疗服务提供者的担忧,他们不能准确把握药物定向。来自本研究的发现表明,许多兴奋剂使用者能够准确把握抗逆转录病毒治疗方法,这样足以避免引起消极的临床后果。抗逆转录病毒疗法能引起一些较好

近日旧金山加州大学新临床研究显示,与那些不使用兴奋剂的感染艾滋病毒的人相比,341名使用冰毒和可卡因的感染艾滋病毒的人通过抗逆转录病毒的方法治疗初步见效。

“艾滋病患者用抗逆转录病毒疗法常常遇到困难,部分原因由于医疗服务提供者的担忧,他们不能准确把握药物定向。来自本研究的发现表明,许多兴奋剂使用者能够准确把握抗逆转录病毒治疗方法,这样足以避免引起消极的临床后果。抗逆转录病毒疗法能引起一些较好的临床效益,包括兴奋剂使用者和非兴奋剂使用者。”Adam W. Carrico博士说。

在Multicenter AIDS Cohort Study研究中,1313名感染艾滋病病毒的男性通过男男性交而患病。“如果我们要实现国家艾滋病战略和联合国艾滋病规划署的结束艾滋病流行的目标,那么我们需要就是在为他们治疗艾滋病的同时鼓励他们停止或减少兴奋剂的使用。这样有效管理滥用兴奋剂与艾滋病的临床护理服务会改善病人状况并减少新发感染。”Carrico说。

旧金山总医院的艾滋病部门创造了一种综合服务递药系统,它可以作为其他诊所的模板。Carrico补充道。艾滋病初级保健诊所应用病人集中团队护理方法,对包括滥用兴奋剂和阿片类药物进行有效管理。

“真正的问题是,病人是否能按照规定使用抗逆转录病毒药物。我们发现在减少或停止兴奋剂使用之前,一些患者开始服用抗逆转录病毒药物,这样的临床效果非常好,这样的变化通常需要更复杂的行为、情感、人际关系和环境变化。”Valerie Gruber博士说。

原始出处:

Carrico AW1, Shoptaw S, Cox C, Stall R, Li X, Ostrow DG, Vlahov D, Plankey MW.Stimulant Use and Progression to AIDS or Mortality After The Initiation of Highly Active Anti-Retroviral Therapy.J Acquir Immune Defic Syndr. 2014 Sep 30. [Epub ahead of print]

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    2015-05-26 仁心济世
  3. 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00:25:00 CST 2014, time=2014-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1365605, encodeId=0156136560547, content=<a href='/topic/show?id=41fa21e036' target=_blank style='color:#2F92EE;'>#AIDS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2170, encryptionId=41fa21e036, topicName=AIDS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbcc223, createdName=cooco, createdTime=Sun Oct 19 00:25:00 CST 2014, time=2014-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554344, encodeId=948e1554344ea, content=<a href='/topic/show?id=d4bf5580e02' target=_blank style='color:#2F92EE;'>#抗逆转录病毒治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55807, encryptionId=d4bf5580e02, topicName=抗逆转录病毒治疗)], attachment=null, 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    2015-04-23 珙桐
  4. 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encodeId=28ff1e47182b0, content=<a href='/topic/show?id=832e93345c3' target=_blank style='color:#2F92EE;'>#转录#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93345, encryptionId=832e93345c3, topicName=转录)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=58df35929710, createdName=mjldent, createdTime=Fri Mar 13 21:25:00 CST 2015, time=2015-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290207, encodeId=4afa129020e4c, content=<a href='/topic/show?id=f774890827' target=_blank style='color:#2F92EE;'>#HIV感染者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8908, encryptionId=f774890827, topicName=HIV感染者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f65b226, createdName=circumcision, createdTime=Sun Oct 19 00:25:00 CST 2014, time=2014-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1365605, encodeId=0156136560547, content=<a href='/topic/show?id=41fa21e036' target=_blank style='color:#2F92EE;'>#AIDS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2170, encryptionId=41fa21e036, topicName=AIDS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbcc223, createdName=cooco, createdTime=Sun Oct 19 00:25:00 CST 2014, time=2014-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554344, encodeId=948e1554344ea, content=<a href='/topic/show?id=d4bf5580e02' target=_blank style='color:#2F92EE;'>#抗逆转录病毒治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55807, encryptionId=d4bf5580e02, topicName=抗逆转录病毒治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=804c14523313, createdName=crystal0567, createdTime=Sun Oct 19 00:25:00 CST 2014, time=2014-10-19, status=1, ipAttribution=)]
    2015-02-13 hxj0117
  5. [GetPortalCommentsPageByObjectIdResponse(id=2053165, encodeId=3c25205316567, content=<a href='/topic/show?id=623294e587c' target=_blank style='color:#2F92EE;'>#逆转录病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94758, encryptionId=623294e587c, topicName=逆转录病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f67438, createdName=xiaogang317, createdTime=Mon Feb 09 04:25:00 CST 2015, time=2015-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2033812, encodeId=427420338125b, content=<a href='/topic/show?id=852b216824' target=_blank style='color:#2F92EE;'>#AID#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2168, encryptionId=852b216824, topicName=AID)], attachment=null, authenticateStatus=null, 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encodeId=28ff1e47182b0, content=<a href='/topic/show?id=832e93345c3' target=_blank style='color:#2F92EE;'>#转录#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93345, encryptionId=832e93345c3, topicName=转录)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=58df35929710, createdName=mjldent, createdTime=Fri Mar 13 21:25:00 CST 2015, time=2015-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290207, encodeId=4afa129020e4c, content=<a href='/topic/show?id=f774890827' target=_blank style='color:#2F92EE;'>#HIV感染者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8908, encryptionId=f774890827, topicName=HIV感染者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f65b226, createdName=circumcision, createdTime=Sun Oct 19 00:25:00 CST 2014, time=2014-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1365605, encodeId=0156136560547, content=<a href='/topic/show?id=41fa21e036' target=_blank style='color:#2F92EE;'>#AIDS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2170, encryptionId=41fa21e036, topicName=AIDS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbcc223, createdName=cooco, createdTime=Sun Oct 19 00:25:00 CST 2014, time=2014-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554344, encodeId=948e1554344ea, content=<a href='/topic/show?id=d4bf5580e02' target=_blank style='color:#2F92EE;'>#抗逆转录病毒治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55807, encryptionId=d4bf5580e02, topicName=抗逆转录病毒治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=804c14523313, createdName=crystal0567, createdTime=Sun Oct 19 00:25:00 CST 2014, time=2014-10-19, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=2053165, encodeId=3c25205316567, content=<a href='/topic/show?id=623294e587c' target=_blank style='color:#2F92EE;'>#逆转录病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94758, encryptionId=623294e587c, topicName=逆转录病毒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f67438, createdName=xiaogang317, createdTime=Mon Feb 09 04:25:00 CST 2015, time=2015-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2033812, encodeId=427420338125b, content=<a href='/topic/show?id=852b216824' target=_blank style='color:#2F92EE;'>#AID#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2168, encryptionId=852b216824, topicName=AID)], attachment=null, authenticateStatus=null, 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encodeId=28ff1e47182b0, content=<a href='/topic/show?id=832e93345c3' target=_blank style='color:#2F92EE;'>#转录#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93345, encryptionId=832e93345c3, topicName=转录)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=58df35929710, createdName=mjldent, createdTime=Fri Mar 13 21:25:00 CST 2015, time=2015-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290207, encodeId=4afa129020e4c, content=<a href='/topic/show?id=f774890827' target=_blank style='color:#2F92EE;'>#HIV感染者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8908, encryptionId=f774890827, topicName=HIV感染者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f65b226, createdName=circumcision, createdTime=Sun Oct 19 00:25:00 CST 2014, time=2014-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1365605, encodeId=0156136560547, content=<a href='/topic/show?id=41fa21e036' target=_blank style='color:#2F92EE;'>#AIDS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2170, encryptionId=41fa21e036, topicName=AIDS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbcc223, createdName=cooco, createdTime=Sun Oct 19 00:25:00 CST 2014, time=2014-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554344, encodeId=948e1554344ea, content=<a href='/topic/show?id=d4bf5580e02' target=_blank style='color:#2F92EE;'>#抗逆转录病毒治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55807, encryptionId=d4bf5580e02, topicName=抗逆转录病毒治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=804c14523313, createdName=crystal0567, createdTime=Sun Oct 19 00:25:00 CST 2014, time=2014-10-19, status=1, ipAttribution=)]
    2015-03-13 mjldent
  7. 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00:25:00 CST 2014, time=2014-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1365605, encodeId=0156136560547, content=<a href='/topic/show?id=41fa21e036' target=_blank style='color:#2F92EE;'>#AIDS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2170, encryptionId=41fa21e036, topicName=AIDS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbcc223, createdName=cooco, createdTime=Sun Oct 19 00:25:00 CST 2014, time=2014-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554344, encodeId=948e1554344ea, content=<a href='/topic/show?id=d4bf5580e02' target=_blank style='color:#2F92EE;'>#抗逆转录病毒治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55807, encryptionId=d4bf5580e02, topicName=抗逆转录病毒治疗)], attachment=null, 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  8. 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00:25:00 CST 2014, time=2014-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1365605, encodeId=0156136560547, content=<a href='/topic/show?id=41fa21e036' target=_blank style='color:#2F92EE;'>#AIDS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2170, encryptionId=41fa21e036, topicName=AIDS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbcc223, createdName=cooco, createdTime=Sun Oct 19 00:25:00 CST 2014, time=2014-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554344, encodeId=948e1554344ea, content=<a href='/topic/show?id=d4bf5580e02' target=_blank style='color:#2F92EE;'>#抗逆转录病毒治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55807, encryptionId=d4bf5580e02, topicName=抗逆转录病毒治疗)], attachment=null, 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    2014-10-19 cooco
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