BMJ Open：先天性心脏病手术量和预后间关系

2015-12-31 Seven L MedSci原创

研究者检索相关数据库，复习相关文献，以探究成人和儿童先天性心脏病手术量与预后之间的关系。纳入了包括手术过程和患者预后等信息量的定量观察和干预研究。在34篇文献中纳入了31篇 (91.2%)回顾性观察性研究，包括1篇关于新生儿病人的研究。25 (73.5%) 篇调查了手术量和死亡率的关系，7 (20.6%篇是死亡率和其他结局的研究，2 (5.9%) 篇非死亡率相关结局研究。其中88.2%的研究来自美

研究者检索相关数据库，复习相关文献，以探究成人和儿童先天性心脏病手术量与预后之间的关系。纳入了包括手术过程和患者预后等信息量的定量观察和干预研究。

在34篇文献中纳入了31篇 (91.2%)回顾性观察性研究，包括1篇关于新生儿病人的研究。25 (73.5%) 篇调查了手术量和死亡率的关系，7 (20.6%篇是死亡率和其他结局的研究，2 (5.9%) 篇非死亡率相关结局研究。其中88.2%的研究来自美国，97%是多中心研究。20 (58.8%) 项研究包含了先天性心脏病情况，14 (41.2%) 项研究包含了单个条件或手术过程。纳入的文献里没有英国相关研究。

大多数研究表明手术量和预后间有关系，但结论存在争议。单一复杂条件手术过程与之关系强烈。手术量和非死亡率间联系的证据不足。除了手术量，病情严重程度、个别情况和外科医生和随着时间推移临床的进展等均会影响患者预后。

观察性研究结果的异质性表明，虽然手术量和患者预后之间的关系存在，但不是一个简单的、独立的、直接的因果关系。

原始出处：

Preston L, Turner J,et al.Is there a relationship between surgical case volume and mortality in congenital heart disease services? A rapid evidence review.BMJ Open. 2015 Dec 18;5(12):e009252.

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2016-09-23 gaoxiaoe

#BMJ#

35 0
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2016-01-24 1de3b290m83(暂无匿称)

突破

120 0
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2016-01-11 三三五五

棒

93 0
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2016-01-09 medsic

好文章

88 0
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2016-01-09 medsic

哦

75 0
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2016-01-09 medsic

值得收藏

137 0
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2016-01-09 medsic

谢谢分享哦

114 0
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2016-10-15 feather89

#PE#

22 0
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2016-01-07 xyfg98

有意思

50 0
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2016-01-07 xyfg98

好文章

140 0

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