Med Sci Monit:假性剥脱综合征患者角膜上皮、基质和内皮的光密度差异

2018-09-09 MedSci MedSci原创

波兰尼古拉斯哥白尼大学Collegium Medicum医学院眼科学系的Urbaniak D近日在Med Sci Monit杂志上发表了一篇文章,他们的研究评估了假性剥脱综合征(PEX)患者中角膜和晶状体前囊的特定层的光密度。

波兰尼古拉斯哥白尼大学Collegium Medicum医学院眼科学系的Urbaniak D近日在Med Sci Monit杂志上发表了一篇文章,他们的研究评估了假性剥脱综合征(PEX)患者中角膜和晶状体前囊的特定层的光密度。

他们将60例白内障和PEX患者(平均年龄76.6±5.6岁,年龄范围62-88岁)与55例无PEX综合征的白内障患者(平均年龄76.3±6.09岁,范围62-90岁)进行比较。在白内障手术之前,使用Oculus的Pentacam HR检查每位患者的眼睛前段。

经过分析,发现PEX组和对照组在角膜上皮、基质和内皮部位的平均光密度分别为25.3±6.09%和19.9±3.41%(P <0.001),23.1±5.5%和19.2±3.6%(P <0.0001),以及14.6±3.4%和12.3±2.1%(P <0.0001)。PEX组的晶状体前囊的光密度为13.6±4.2%,对照组为9.74±2.23%(P <0.0001)。PEX组和对照组角膜的平均厚度分别为555μm和556μm,内皮细胞的平均光密度分别为2240 / mm 2和2323 / mm 2(P <0.05)。

因此,他们认为,在PEX患者中,不仅可以通过裂隙灯检测到具有假粘连的结构,而且还可以在角膜上皮和基质中观察到光密度增加。同时,作者指出,光密度的增加与内皮细胞密度的降低或中央角膜厚度的增加无关。

原文出处:

Urbaniak, D., et al., Scheimpflug Camera Measurement of Optical Density of the Corneal Epithelium, Stroma, and Endothelium in Patients with Pseudoexfoliation Syndrome. Med Sci Monit, 2018. 24: p. 5826-5831.

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    2018-09-11 snowpeakxu
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    2018-09-09 ylzr123

    认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。给点赞啦

    0