Blood Rev:使用光学相干断层扫描血管造影术来研究镰状细胞视网膜病变的研究进展

2019-05-17 不详 网络

巴西Bahiana医学与公共卫生学院眼科的LeitaoGuerraRL等人近日在Blood Rev杂志上发表了一篇综述性文章,对镰状细胞视网膜病变(SCR)的诊断,尤其是通过光学相干断层扫描血管造影技术的研究进展进行了综述。

巴西Bahiana医学与公共卫生学院眼科的LeitaoGuerraRL等人近日在Blood Rev杂志上发表了一篇综述性文章,对镰状细胞视网膜病变(SCR)的诊断,尤其是通过光学相干断层扫描血管造影技术的研究进展进行了综述。

四十多年来,人们一直在努力建立镰状细胞视网膜病变(SCR)的评估标准,试图根据戈德堡的分类(1971)来确定外周高危血管的异常。黄斑是视网膜中心的一个区域,负责高分辨率的中心视觉,并且还受到SCR的影响。随着视网膜成像技术的发展,黄斑成为镰状细胞病(SCD)研究的主要焦点。光学相干断层扫描血管造影是一种现代的非侵入性方法,可以对黄斑区域中的视网膜血管网络进行定性和定量分析。

研究者总共筛选出86项关于SCD和光学相干断层扫描血管造影的研究。其中12个符合研究的纳入标准。镰状细胞黄斑病变的患病率在SCD人群中为45.6%,并且随年龄增长而增加。

综上,研究者对主要的血管特征、视觉障碍和病理生理学、基因型和外周高危血管异常等进行了讨论,并对血液学专家、全科医生和儿科医生在治疗中的作用进行了评价。

原文出处:

LeitaoGuerraRL., et al., Progress in the study of sickle cell retinopathy using optical coherence tomography angiography. Blood Rev, 2019.

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    2019-05-19 zutt
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    2019-05-19 sodoo
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