Arthritis Rheumatol:自身免疫性风湿病的选择性终止妊娠

2020-03-19 xiangting MedSci原创

许多ARD患者接受ETOP;并发症很少见。在符合医学指征的ETOP中,没有异常并发症或疾病发作的不良信号。

这项研究旨在提供有关在两个转诊数据库随访的自身免疫性风湿病(ARD)女性患者选择性终止妊娠(ETOP)的发生率和安全性的参考数据。

检索了两个大型数据库,即关注妊娠的转诊ARD临床实践(BVC)以及一项对SLE和抗磷脂抗体相关妊娠(PROMISSE)的观察性研究,以了解既往ETOP病史和与ETOP相关的并发症。

既往怀孕的女性中,BVC数据库的1,307例女性中有21.7%,PROMISSE数据库的297例患者中有25.3%有1-5次的既往ETOPs病史。BVC患者未报告因ETOP引起的发作或住院并发症。在674例意外怀孕中, 15例(2%)因胎儿或产妇原因被建议终止妊娠;其中,有2例胎儿在手术前死亡;1例女性患者拒绝终止妊娠,并且尽管重病仍成功分娩。3年后,该患者死于心肌病。

许多ARD患者接受ETOP;并发症很少见。在符合医学指征的ETOP中,没有异常并发症或疾病发作的不良信号。

原始出处:

Michael D. Lockshin. Elective termination of pregnancy in autoimmune rheumatic diseases. Arthritis Rheumatol. March 2020.

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    2020-03-21 zhaojie88
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