近端胃癌根治术后早期复发危险因素

2012-06-23 小哲 摘编 医学论坛网

  近日,天津医科大学附属肿瘤医院胃部肿瘤科、天津市肿瘤防治重点实验室李昉璇、张汝鹏、刘辉等人共同发表论文,旨在探讨近端胃癌根治术后早期复发(2年内)的危险因素。研究指出,对原发肿瘤浸润深度达T3以上、病理类型为腺鳞癌的近端胃癌患者,应适当扩大手术切除范围、积极行标准或扩大的淋巴结清扫,于术中或术后常规加行辅助治疗。该文发表在2012年第15卷第2期《中华胃肠外科杂志》上。   回顾性分析200

  近日,天津医科大学附属肿瘤医院胃部肿瘤科、天津市肿瘤防治重点实验室李昉璇、张汝鹏、刘辉等人共同发表论文,旨在探讨近端胃癌根治术后早期复发(2年内)的危险因素。研究指出,对原发肿瘤浸润深度达T3以上、病理类型为腺鳞癌的近端胃癌患者,应适当扩大手术切除范围、积极行标准或扩大的淋巴结清扫,于术中或术后常规加行辅助治疗。该文发表在2012年第15卷第2期《中华胃肠外科杂志》上。

  回顾性分析2000年1月至2006年5月年间天津医科大学附属肿瘤医院行根治性切除、且有完整随访资料的367例近端胃癌患者的临床资料,其中术后早期复发71例。通过单因素和多因素分析来明确近端胃癌术后早期复发的危险因素。

  早期复发危险因素的单因素分析结果显示,Borrmann分型、病理类型、浸润深度和阴性淋巴结数与近端胃癌早期复发有关;多因素分析显示,病理类型、浸润深度和阴性淋巴结数是近端胃癌早期复发的独立危险因素。早期复发患者的阴性淋巴结数明显低于无早期复发者。
    

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    2012-06-25 hittouch
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    2012-06-25 jeanqiuqiu