BMC Res Notes:血清肌酐正常的成人门诊患者的肾功能评估结果

2020-03-02 不详 网络

本研究旨在评估使用估计的肾小球滤过率(eGFR)正常的患者的肾小球滤过率评估肾功能不全的患病率。研究共纳入414名SCr正常的患者。使用MDRD方程计算的平均GFR(ml/min/1.73 m2)为116.8±43.5,根据C-G公式为90.5±33.1。根据MDRD公式,21.5%的患者轻度肾功能不全(即eGFR 60-89.9 ml/min/1.73 m2),7.7%的患者中度肾功能不全(即e

本研究旨在评估使用估计的肾小球滤过率(eGFR)正常的患者的肾小球滤过率评估肾功能不全的患病率。

研究共纳入414名SCr正常的患者。使用MDRD方程计算的平均GFR(ml/min/1.73 m2)为116.8±43.5,根据C-G公式为90.5±33.1。根据MDRD公式,21.5%的患者轻度肾功能不全(即eGFR 60-89.9 ml/min/1.73 m2),7.7%的患者中度肾功能不全(即eGFR 30-59.9 ml/min/1.73 m2)。根据Cockcroft-Gault(C-G)公式,SCr正常的患者中发现轻度肾功能不全的占38.2%,中度肾功能不全的占16.9%。在多变量分析中,年龄,女性,肾脏疾病或其他慢性疾病的家族病史以及高收缩压与普遍的肾功能不全有关,这取决于用于估算GFR的公式。

总之,这项研究表明,在患有正常SCr的埃塞俄比亚成年门诊患者中,肾功能受损的患病率很高。在常规实验室报告中包括对GFR的估算值可能有助于促进识别,从而优化肾功能不全患者的治疗。

原始出处:

Temesgen Fiseha, Tizita Mengesha, et al., Estimation of renal function in adult outpatients with normal serum creatinine. BMC Res Notes. 2019; 12: 462. doi: 10.1186/s13104-019-4487-6

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    2020-12-06 yese
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    2020-03-03 俅侠