Dig Dis Sci:酸性咽反流与喉反流引起的症状和喉部损伤无关

2019-06-10 不详 MedSci原创

当酸性胃食管反流(GER)进入喉部时会出现喉咽反流(LPR)症状。然而,LPR强度与症状和喉部损伤之间的关系尚未明确。因此,本项研究我们旨在限制混杂因素以分析LPR与症状和喉部损伤之间的关系。

背景
当酸性食管反流(GER)进入喉部时会出现喉咽反流(LPR)症状。然而,LPR强度与症状和喉部损伤之间的关系尚未明确。因此,本项研究我们旨在限制混杂因素以分析LPR与症状和喉部损伤之间的关系。

方法
研究人员使用双咽和远端食管24小时pH值监测仪来监测咽部反流的GER起源,评估整个酸度范围(pH <6,pH <5.5,pH <5.0) 持续30天。

结果
咽部反流静止期pH值为14,咽部反流急性发作时pH值为4,pH <6.0和pH <5.5较为多见。pH <5.0的咽部反流是罕见的。综合分析未发现症状(反流症状指数)或喉部损伤(反流发现评分)与任何pH水平的咽部反流发作次数或咽酸暴露持续时间之间的任何相关性。

结论
本项研究结果未发现酸性咽反流与LPR引起的症状或喉部损伤之间存在任何关系。

原始出处:

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    2019-06-12 feifers