JACC:CABG术前血糖控制不良会出现不良预后

2015-08-04 徐媛媛译 MedSci原创

1型糖尿病(T1DM)患者发生心血管事件的风险很高。本研究旨在研究1型糖尿病患者CABG术前血糖控制不良是否会增加长期全因死亡及严重不良心血管事件(MACE)风险。 研究人员收纳了来自瑞典糖尿病研究注册中心的764名1型糖尿病患者。在平均4.7年的随访中,334名(44%)患者死亡或发生MACE事件(发病率:82/1000人/年)。调整多变量后,与对照组(HbA1c>7.0%)相比,1型糖尿病患

1型糖尿病(T1DM)患者发生心血管事件的风险很高。本研究旨在研究1型糖尿病患者CABG术前血糖控制不良是否会增加长期全因死亡及严重不良心血管事件(MACE)风险。

研究人员收纳了来自瑞典糖尿病研究注册中心的764名1型糖尿病患者。在平均4.7年的随访中,334名(44%)患者死亡或发生MACE事件(发病率:82/1000人/年)。调整多变量后,与对照组(HbA1c>7.0%)相比,1型糖尿病患者术前HbAc1水平较高(>10%)会使死亡及MACE风险增加2倍以上。术前HbAc1较高者死亡或MACE风险明显高于血糖控制良好患者。HbAc1最高组中CABG术后因低血糖住院的患者术最多(17% vs. 15%),使用Cox模型校正多个变量后发现,HbAc1每升高1%时的风险比为1.18(95% CI 1.06~1.32;P=0.002)。

研究表明,1型糖尿病患者CABG术前血糖控制不良会增加长期全因死亡及严重不良心血管事件(MACE)风险。

原始出处

Nyström T1, Holzmann MJ2, Eliasson B3, Kuhl J4, Sartipy U5.Glycemic Control in Type 1 Diabetes and Long-Term Risk of Cardiovascular Events or Death After Coronary Artery Bypass Grafting.J Am Coll Cardiol. 2015 Aug 4

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    2016-01-04 hbwxf
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    2015-08-04 owlhealth

    同意楼上

    0

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    2015-08-04 lovetcm

    术前控制血糖其实非常关键不仅仅是搭桥手术了,就是常规手术也应该控制血糖。

    0

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