Clin Endocrinol:男性不孕不育健康危害多

2016-03-15 Mechront 译 MedSci原创

研究者进行了一项横断面的病例对照研究,纳入了192名不孕不育男性,年龄18-50岁,精子浓度 <20 × 106/ml,同时基于人口按年龄匹配199名对照组,探究不孕不育年轻男性的性腺机能减退的发病率和其与代谢、骨相关指标的关系。以总睾酮<8·0 nmol/l和/或促黄体激素 ≥8·6 IU/l和/或持续进行雄激素替代疗法定义为性腺机能减退。研究者检测了参与者血清性激素、血脂、血糖、胰

研究者进行了一项横断面的病例对照研究,纳入了192名不孕不育男性,年龄18-50岁,精子浓度 <20 × 106/ml,同时基于人口按年龄匹配199名对照组,探究不孕不育年轻男性的性腺机能减退的发病率和其与代谢、骨相关指标的关系。

以总睾酮<8·0 nmol/l和/或促黄体激素 ≥8·6 IU/l和/或持续进行雄激素替代疗法定义为性腺机能减退。研究者检测了参与者血清性激素、血脂、血糖、胰岛素、糖化血红蛋白等代谢相关指标,以及骨密度(BMD)。

与对照组相比,不孕不育男性,其性腺机能减退的风险更高(OR 10; 95% CI, 5.1, 22),尤其是非梗阻性无精子症患者,风险最高。性腺机能减退的男性,其糖化血红蛋白含量更高(MD 2.8 mmol/mol; 95% CI, 0.64, 4.9; P = 0.011),腰椎BMD更低(MD 0.05 g/cm2; 95% CI, 0.01, 0.10; P = 0.032)。伴有低睾酮水平的不孕不育男性,与正常生育能力男性相比,这些差异更显著。

研究结果表明,年轻不孕不育男性其性腺机能减退的风险是正常生育男性的10倍,不仅如此,性腺机能减退还会导致更高的糖化血红蛋白水平和更低的BMD。在对不孕不育男性的管理中,如果有需要应进行内分泌评估,及早发现问题并进行干预,以降低代谢后遗症和骨质疏松症风险。

原始出处:

Johannes Bobjer, Karolina Bogefors,et al.High prevalence of hypogonadism and associated impaired metabolic and bone mineral status in subfertile men.Clinical Endocrinology.Published online 29 February 2016

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    2016-04-03 inter158

    不孕不育年轻男性的性腺机能减退的发病率和其与代谢、骨相关指标的关系。

    0

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    2016-03-27 1de8c9efm46(暂无匿称)

    试管婴儿越来越多

    0

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    2016-03-22 kingjiang

    可以写篇文章探讨一下这个问题

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1973474, encodeId=b6ab19e3474a8, content=<a href='/topic/show?id=20952e77045' target=_blank style='color:#2F92EE;'>#健康危害#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27770, encryptionId=20952e77045, topicName=健康危害)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b632500090, createdName=h.y200607_23674418, createdTime=Sat Nov 26 10:17:00 CST 2016, time=2016-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=75303, encodeId=52cbe530307, content=不孕不育年轻男性的性腺机能减退的发病率和其与代谢、骨相关指标的关系。, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151226/IMG567EB873985DE3928.jpg, createdBy=ea941622301, createdName=inter158, createdTime=Sun Apr 03 00:34:00 CST 2016, time=2016-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73969, encodeId=ebb0e396917, content=试管婴儿越来越多, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5dd51704841, createdName=1de8c9efm46(暂无匿称), createdTime=Sun Mar 27 08:59:00 CST 2016, time=2016-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72500, encodeId=b489e250041, content=可以写篇文章探讨一下这个问题, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erJaiboOUVrGYoHV8Essd0EJvx0DPLDeqP3qkvaGD39DdvMmzT98iaib209rApLicEN84Nu8RefibOh8jA/132, createdBy=75ba1609552, createdName=kingjiang, createdTime=Tue Mar 22 00:10:00 CST 2016, time=2016-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71979, encodeId=3c6be197917, content=目前不孕不育患者也呈上升趋势!, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Sun Mar 20 10:30:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355075, encodeId=a89b13550e589, content=<a href='/topic/show?id=b9e02036159' target=_blank style='color:#2F92EE;'>#不孕不育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20361, encryptionId=b9e02036159, topicName=不孕不育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Mar 17 11:17:00 CST 2016, time=2016-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=69619, encodeId=7603696195c, content=肾为后天, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9a01693879, createdName=任然, createdTime=Wed Mar 16 13:18:00 CST 2016, time=2016-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=69620, encodeId=53f369620b1, content=之本, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9a01693879, createdName=任然, createdTime=Wed Mar 16 13:18:00 CST 2016, time=2016-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=69618, encodeId=c7626961846, content=好的吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9a01693879, createdName=任然, createdTime=Wed Mar 16 13:17:00 CST 2016, time=2016-03-16, status=1, ipAttribution=)]
    2016-03-20 Lisa971

    目前不孕不育患者也呈上升趋势!

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1973474, encodeId=b6ab19e3474a8, content=<a href='/topic/show?id=20952e77045' target=_blank style='color:#2F92EE;'>#健康危害#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27770, encryptionId=20952e77045, topicName=健康危害)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b632500090, createdName=h.y200607_23674418, createdTime=Sat Nov 26 10:17:00 CST 2016, time=2016-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=75303, encodeId=52cbe530307, content=不孕不育年轻男性的性腺机能减退的发病率和其与代谢、骨相关指标的关系。, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151226/IMG567EB873985DE3928.jpg, createdBy=ea941622301, createdName=inter158, createdTime=Sun Apr 03 00:34:00 CST 2016, time=2016-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73969, encodeId=ebb0e396917, content=试管婴儿越来越多, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5dd51704841, createdName=1de8c9efm46(暂无匿称), createdTime=Sun Mar 27 08:59:00 CST 2016, time=2016-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72500, encodeId=b489e250041, content=可以写篇文章探讨一下这个问题, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erJaiboOUVrGYoHV8Essd0EJvx0DPLDeqP3qkvaGD39DdvMmzT98iaib209rApLicEN84Nu8RefibOh8jA/132, createdBy=75ba1609552, createdName=kingjiang, createdTime=Tue Mar 22 00:10:00 CST 2016, time=2016-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71979, encodeId=3c6be197917, content=目前不孕不育患者也呈上升趋势!, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Sun Mar 20 10:30:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355075, encodeId=a89b13550e589, content=<a href='/topic/show?id=b9e02036159' target=_blank style='color:#2F92EE;'>#不孕不育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20361, encryptionId=b9e02036159, topicName=不孕不育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Mar 17 11:17:00 CST 2016, time=2016-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=69619, encodeId=7603696195c, content=肾为后天, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9a01693879, createdName=任然, createdTime=Wed Mar 16 13:18:00 CST 2016, time=2016-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=69620, encodeId=53f369620b1, content=之本, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9a01693879, createdName=任然, createdTime=Wed Mar 16 13:18:00 CST 2016, time=2016-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=69618, encodeId=c7626961846, content=好的吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9a01693879, createdName=任然, createdTime=Wed Mar 16 13:17:00 CST 2016, time=2016-03-16, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1973474, encodeId=b6ab19e3474a8, content=<a href='/topic/show?id=20952e77045' target=_blank style='color:#2F92EE;'>#健康危害#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27770, encryptionId=20952e77045, topicName=健康危害)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b632500090, createdName=h.y200607_23674418, createdTime=Sat Nov 26 10:17:00 CST 2016, time=2016-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=75303, encodeId=52cbe530307, content=不孕不育年轻男性的性腺机能减退的发病率和其与代谢、骨相关指标的关系。, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151226/IMG567EB873985DE3928.jpg, createdBy=ea941622301, createdName=inter158, createdTime=Sun Apr 03 00:34:00 CST 2016, time=2016-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73969, encodeId=ebb0e396917, content=试管婴儿越来越多, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5dd51704841, createdName=1de8c9efm46(暂无匿称), createdTime=Sun Mar 27 08:59:00 CST 2016, time=2016-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72500, encodeId=b489e250041, content=可以写篇文章探讨一下这个问题, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erJaiboOUVrGYoHV8Essd0EJvx0DPLDeqP3qkvaGD39DdvMmzT98iaib209rApLicEN84Nu8RefibOh8jA/132, createdBy=75ba1609552, createdName=kingjiang, createdTime=Tue Mar 22 00:10:00 CST 2016, time=2016-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71979, encodeId=3c6be197917, content=目前不孕不育患者也呈上升趋势!, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Sun Mar 20 10:30:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355075, encodeId=a89b13550e589, content=<a href='/topic/show?id=b9e02036159' target=_blank style='color:#2F92EE;'>#不孕不育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20361, encryptionId=b9e02036159, topicName=不孕不育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Mar 17 11:17:00 CST 2016, time=2016-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=69619, encodeId=7603696195c, content=肾为后天, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9a01693879, createdName=任然, createdTime=Wed Mar 16 13:18:00 CST 2016, time=2016-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=69620, encodeId=53f369620b1, content=之本, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9a01693879, createdName=任然, createdTime=Wed Mar 16 13:18:00 CST 2016, time=2016-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=69618, encodeId=c7626961846, content=好的吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9a01693879, createdName=任然, createdTime=Wed Mar 16 13:17:00 CST 2016, time=2016-03-16, status=1, ipAttribution=)]
    2016-03-16 任然

    肾为后天

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1973474, encodeId=b6ab19e3474a8, content=<a href='/topic/show?id=20952e77045' target=_blank style='color:#2F92EE;'>#健康危害#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27770, encryptionId=20952e77045, topicName=健康危害)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b632500090, createdName=h.y200607_23674418, createdTime=Sat Nov 26 10:17:00 CST 2016, time=2016-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=75303, encodeId=52cbe530307, content=不孕不育年轻男性的性腺机能减退的发病率和其与代谢、骨相关指标的关系。, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151226/IMG567EB873985DE3928.jpg, createdBy=ea941622301, createdName=inter158, createdTime=Sun Apr 03 00:34:00 CST 2016, time=2016-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73969, encodeId=ebb0e396917, content=试管婴儿越来越多, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5dd51704841, createdName=1de8c9efm46(暂无匿称), createdTime=Sun Mar 27 08:59:00 CST 2016, time=2016-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72500, encodeId=b489e250041, content=可以写篇文章探讨一下这个问题, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erJaiboOUVrGYoHV8Essd0EJvx0DPLDeqP3qkvaGD39DdvMmzT98iaib209rApLicEN84Nu8RefibOh8jA/132, createdBy=75ba1609552, createdName=kingjiang, createdTime=Tue Mar 22 00:10:00 CST 2016, time=2016-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71979, encodeId=3c6be197917, content=目前不孕不育患者也呈上升趋势!, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Sun Mar 20 10:30:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355075, encodeId=a89b13550e589, content=<a href='/topic/show?id=b9e02036159' target=_blank style='color:#2F92EE;'>#不孕不育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20361, encryptionId=b9e02036159, topicName=不孕不育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Mar 17 11:17:00 CST 2016, time=2016-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=69619, encodeId=7603696195c, content=肾为后天, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9a01693879, createdName=任然, createdTime=Wed Mar 16 13:18:00 CST 2016, time=2016-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=69620, encodeId=53f369620b1, content=之本, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9a01693879, createdName=任然, createdTime=Wed Mar 16 13:18:00 CST 2016, time=2016-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=69618, encodeId=c7626961846, content=好的吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9a01693879, createdName=任然, createdTime=Wed Mar 16 13:17:00 CST 2016, time=2016-03-16, status=1, ipAttribution=)]
    2016-03-16 任然

    之本

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1973474, encodeId=b6ab19e3474a8, content=<a href='/topic/show?id=20952e77045' target=_blank style='color:#2F92EE;'>#健康危害#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27770, encryptionId=20952e77045, topicName=健康危害)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b632500090, createdName=h.y200607_23674418, createdTime=Sat Nov 26 10:17:00 CST 2016, time=2016-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=75303, encodeId=52cbe530307, content=不孕不育年轻男性的性腺机能减退的发病率和其与代谢、骨相关指标的关系。, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151226/IMG567EB873985DE3928.jpg, createdBy=ea941622301, createdName=inter158, createdTime=Sun Apr 03 00:34:00 CST 2016, time=2016-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73969, encodeId=ebb0e396917, content=试管婴儿越来越多, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5dd51704841, createdName=1de8c9efm46(暂无匿称), createdTime=Sun Mar 27 08:59:00 CST 2016, time=2016-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72500, encodeId=b489e250041, content=可以写篇文章探讨一下这个问题, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erJaiboOUVrGYoHV8Essd0EJvx0DPLDeqP3qkvaGD39DdvMmzT98iaib209rApLicEN84Nu8RefibOh8jA/132, createdBy=75ba1609552, createdName=kingjiang, createdTime=Tue Mar 22 00:10:00 CST 2016, time=2016-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71979, encodeId=3c6be197917, content=目前不孕不育患者也呈上升趋势!, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160313/IMG56E50DEC424F44672.jpg, createdBy=ce5b1699635, createdName=Lisa971, createdTime=Sun Mar 20 10:30:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355075, encodeId=a89b13550e589, content=<a href='/topic/show?id=b9e02036159' target=_blank style='color:#2F92EE;'>#不孕不育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20361, encryptionId=b9e02036159, topicName=不孕不育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Mar 17 11:17:00 CST 2016, time=2016-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=69619, encodeId=7603696195c, content=肾为后天, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9a01693879, createdName=任然, createdTime=Wed Mar 16 13:18:00 CST 2016, time=2016-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=69620, encodeId=53f369620b1, content=之本, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9a01693879, createdName=任然, createdTime=Wed Mar 16 13:18:00 CST 2016, time=2016-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=69618, encodeId=c7626961846, content=好的吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9a01693879, createdName=任然, createdTime=Wed Mar 16 13:17:00 CST 2016, time=2016-03-16, status=1, ipAttribution=)]
    2016-03-16 任然

    好的吧

    0

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