New Engl J Med:抗艾滋病治疗失败的根本原因是什么?

2017-10-29 佚名 medicalxpress

根据10月25日在新英格兰医学杂志上发表的一篇透视文章,抗逆转录病毒治疗(ART)的抗药性威胁着最近得到治疗的新的艾滋病毒感染率。

根据10月25日在新英格兰医学杂志上发表的一篇透视文章,抗逆转录病毒治疗(ART)的抗药性威胁着最近得到治疗的新的艾滋病毒感染率。

来自纽约州霍普金斯大学彭博社巴尔的摩公共卫生学院的ChrisBeyrer先生,以及来自伦敦切尔西和威斯敏斯特医院的AntonPozniak,M.D.讨论了艾滋病毒耐药性的出现,对艾滋病毒治疗的积极影响构成威胁。

研究人员指出,自全球引入抗逆转录病毒治疗以来,艾滋病毒耐药性的普及率已从11%增加到29%。在接受调查的11个国家中,有6个国家的预防药物耐药率首次超过了10%。世界卫生组织(WHO)提出了一项监测,打击和预防耐药性五项全球计划。建议支持和改进现有计划的方法包括扩大病毒载量监测能力的重要部署,以确保及早转用有效的抗逆转录病毒疗法,并改善参与护理和遵守抗逆转录病毒治疗。除了这些建议的执行之外,另一个步骤将包括采用具有较高遗传基因阻力的较新方案。

作者写道:“耐药性是艾滋病项目失败的标志之一。“它所造成的威胁在于个体患者的临床治疗将会失败,那些疾病继续感染的病毒血症患者的社区将面临风险。”

原始出处:

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1785497, encodeId=e5011e85497c5, content=<a href='/topic/show?id=34b86e91f9' target=_blank style='color:#2F92EE;'>#Engl#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6791, encryptionId=34b86e91f9, topicName=Engl)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7eeb2500172, createdName=haouestc, createdTime=Sat Sep 01 06:52:00 CST 2018, time=2018-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2081414, encodeId=2aa62081414e7, content=<a href='/topic/show?id=57406e8506' target=_blank style='color:#2F92EE;'>#Eng#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6785, encryptionId=57406e8506, topicName=Eng)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Thu Sep 06 05:52:00 CST 2018, time=2018-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1717268, encodeId=4a3d1e17268e6, content=<a href='/topic/show?id=e3436460313' target=_blank style='color:#2F92EE;'>#治疗失败#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64603, encryptionId=e3436460313, topicName=治疗失败)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b1c332383811, createdName=ligang4450, createdTime=Tue Jul 31 00:52:00 CST 2018, time=2018-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608186, encodeId=6cf6160818678, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue Oct 31 08:52:00 CST 2017, time=2017-10-31, status=1, ipAttribution=)]
    2018-09-01 haouestc
  2. [GetPortalCommentsPageByObjectIdResponse(id=1785497, encodeId=e5011e85497c5, content=<a href='/topic/show?id=34b86e91f9' target=_blank style='color:#2F92EE;'>#Engl#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6791, encryptionId=34b86e91f9, topicName=Engl)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7eeb2500172, createdName=haouestc, createdTime=Sat Sep 01 06:52:00 CST 2018, time=2018-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2081414, encodeId=2aa62081414e7, content=<a href='/topic/show?id=57406e8506' target=_blank style='color:#2F92EE;'>#Eng#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6785, encryptionId=57406e8506, topicName=Eng)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Thu Sep 06 05:52:00 CST 2018, time=2018-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1717268, encodeId=4a3d1e17268e6, content=<a href='/topic/show?id=e3436460313' target=_blank style='color:#2F92EE;'>#治疗失败#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64603, encryptionId=e3436460313, topicName=治疗失败)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b1c332383811, createdName=ligang4450, createdTime=Tue Jul 31 00:52:00 CST 2018, time=2018-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608186, encodeId=6cf6160818678, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue Oct 31 08:52:00 CST 2017, time=2017-10-31, status=1, ipAttribution=)]
    2018-09-06 spoonycyy
  3. [GetPortalCommentsPageByObjectIdResponse(id=1785497, encodeId=e5011e85497c5, content=<a href='/topic/show?id=34b86e91f9' target=_blank style='color:#2F92EE;'>#Engl#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6791, encryptionId=34b86e91f9, topicName=Engl)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7eeb2500172, createdName=haouestc, createdTime=Sat Sep 01 06:52:00 CST 2018, time=2018-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2081414, encodeId=2aa62081414e7, content=<a href='/topic/show?id=57406e8506' target=_blank style='color:#2F92EE;'>#Eng#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6785, encryptionId=57406e8506, topicName=Eng)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Thu Sep 06 05:52:00 CST 2018, time=2018-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1717268, encodeId=4a3d1e17268e6, content=<a href='/topic/show?id=e3436460313' target=_blank style='color:#2F92EE;'>#治疗失败#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64603, encryptionId=e3436460313, topicName=治疗失败)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b1c332383811, createdName=ligang4450, createdTime=Tue Jul 31 00:52:00 CST 2018, time=2018-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608186, encodeId=6cf6160818678, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue Oct 31 08:52:00 CST 2017, time=2017-10-31, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1785497, encodeId=e5011e85497c5, content=<a href='/topic/show?id=34b86e91f9' target=_blank style='color:#2F92EE;'>#Engl#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6791, encryptionId=34b86e91f9, topicName=Engl)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7eeb2500172, createdName=haouestc, createdTime=Sat Sep 01 06:52:00 CST 2018, time=2018-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2081414, encodeId=2aa62081414e7, content=<a href='/topic/show?id=57406e8506' target=_blank style='color:#2F92EE;'>#Eng#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6785, encryptionId=57406e8506, topicName=Eng)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Thu Sep 06 05:52:00 CST 2018, time=2018-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1717268, encodeId=4a3d1e17268e6, content=<a href='/topic/show?id=e3436460313' target=_blank style='color:#2F92EE;'>#治疗失败#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64603, encryptionId=e3436460313, topicName=治疗失败)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b1c332383811, createdName=ligang4450, createdTime=Tue Jul 31 00:52:00 CST 2018, time=2018-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608186, encodeId=6cf6160818678, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue Oct 31 08:52:00 CST 2017, time=2017-10-31, status=1, ipAttribution=)]

相关资讯

CRISPR将以7大方式改变世界:治愈癌症,消灭艾滋病……

据TechCrunch报道,如果你有能力,你会帮助根除癌症吗?帮助打造没有HIV的世界?亦或是消灭携带寨卡病毒的蚊子吗?最新基因编辑技术CRISPR正帮助科学家通过精确手术剪掉多余的DNA片段,它可能会在不久的将来从根本上改变我们的世界。

彭丽媛出席艾滋病校园宣传活动

9月5日,国家主席习近平夫人彭丽媛邀请出席金砖国家领导人第九次会晤和新兴市场国家与发展中国家对话会外方代表团团长夫人共同出席“‘美好青春我做主’艾滋病防治宣传校园行——走进厦门大学”活动。

Lancet psychiat:精神病患者中艾滋、乙肝和丙肝的发病率研究

重度精神病会增加发病率和死亡率。在重度精神病患者中血源性病毒(BBVs)的患病风险增加。

PNAS:确定艾滋病毒发展和传播的“根源”,全新治疗方案即将问世

美国西北医学院的一项研究发现,人类免疫缺陷病毒(HIV)使用名为透明甲酸精(DRFs)的蛋白质劫持健康细胞的细胞骨架,这一发现加深了了解艾滋病毒感染,以及开发潜在治疗目标的新方法。

Science:为何女性感染艾滋病防不胜防?根源原来在这里!

一些特定种类的阴道微生物对预防HIV感染用品的干扰作用。据报道,每年HIV感染者中的女性人数超过百万,此次研究的目的是基于了解替诺福韦对预防艾滋病感染的作用。 在使用药物预防艾滋病感染的进程中,男性的成功率非常高,而女性的药物预防作用令人失望,在2010年的一份报道中指出,女性使用替诺福韦可以使艾滋病感染率降低39%。 在此次研究中,参与者均为HIV感染者,并且经常使用替诺福韦

Lancet oncol:精神病患者中艾滋、乙肝和丙肝的发病率和风险因子

精神病患者中艾滋、乙肝和丙肝的发病率和风险因子