Diabetes Care:2型糖尿病QT间期可独立预测死亡风险

2014-03-07 永燊 编译 中国医学论坛报糖尿病手机报

美国糖尿病心脏研究(Diabetes Heart Study)显示,在2型糖尿病人群中,心率校正QT(QTc)间期是全因死亡及心血管病(CVD)死亡的独立预测因素。论文2月26日在线发表于《糖尿病护理》(Diabetes Care)杂志。研究者纳入1020例2型糖尿病患者,基线时这些患者没有心房颤动、严重心室传导障碍及没有接受抗心律失常治疗。中位随访8.5年后,204例患者死亡。在校正多变量模型中

美国糖尿病心脏研究(Diabetes Heart Study)显示,在2型糖尿病人群中,心率校正QT(QTc)间期是全因死亡及心血管病(CVD)死亡的独立预测因素。论文2月26日在线发表于《糖尿病护理》(Diabetes Care)杂志。

研究者纳入1020例2型糖尿病患者,基线时这些患者没有心房颤动、严重心室传导障碍及没有接受抗心律失常治疗。中位随访8.5年后,204例患者死亡。在校正多变量模型中,QTc间期每增加一个标准差(SD)与全因死亡风险升高18%及CVD死亡风险升高29%相关。

原始出处:
Amanda J. Cox1,2,3, Amir Azeem4, Joseph Yeboah4, Elsayed Z. Soliman5, Shivani R. Aggarwal4, Alain G. Bertoni5, J. Jeffrey Carr6, Barry I. Freedman7, David M. Herrington4 and Donald W. Bowden1,2,3⇑.Heart Rate–Corrected QT Interval Is an Independent Predictor of All-Cause and Cardiovascular Mortality in Individuals With Type 2 Diabetes: The Diabetes Heart Study.Diabetes Care February 26, 2014 doi: 10.2337/dc13-1257

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    2014-06-20 智智灵药
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    2014-03-09 xinmeili

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