大咖谈 | PET显像预测和评价恶性黑色素瘤免疫治疗疗效的价值

2023-10-23 iCombo iCombo 发表于上海

PET/CT是通过正电子核素标记的生命代谢必须的小分子物质，基于示踪原理显示活体内组织细胞的功能代谢变化的一类显像技术，在清晰显示病灶形态基础上分析研究病变组织的代谢功能变化。

导读

PET/CT是通过正电子核素标记的生命代谢必须的小分子物质，基于示踪原理显示活体内组织细胞的功能代谢变化的一类显像技术，在清晰显示病灶形态基础上分析研究病变组织的代谢功能变化。正电子显像药物很多，其中18F-FDG是最常用的显像剂。18F-FDG是葡萄糖的类似物，能够反映组织细胞和器官对葡萄糖利用能力。恶性黑色素瘤细胞增殖活跃，对葡萄糖利用度高，呈18F-FDG高代谢，在PET图像上有增殖活性病灶表现为放射性浓聚；而肿瘤组织经过治疗后有活性的肿瘤细胞被杀灭，PET显像表现为放射性浓聚程度明显减低或恢复到本底水平。18F-FDG PET/CT显像适用于恶性黑色素瘤治疗前分期，治疗早期疗效预测及评估疗效。

免疫检查点抑制剂治疗改善了恶性黑色素瘤患者的无进展生存期和总生存期，但免疫反应模式复杂多样，仅依靠病灶大小的改变难以准确评价疗效。18F-FDG PET/CT显像在肿瘤治疗早期能通过治疗前后代谢的改变预测疗效，筛选治疗应答者。在免疫治疗12个月后，PET/CT扫描可用来评价疗效，显像阴性达到完全缓解者可考虑停用免疫治疗。

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2023-10-24 ms8000001184766686 来自河北省

我觉得治疗胃癌的关键可能在脾脏

25 0
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2023-10-24 ms8000001184766686 来自河北省

要是不发生肿瘤为什么

29 0
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2023-10-24 ms8000001184766686 来自河北省

心脏和小肠能发生肿瘤吗

23 0
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2023-10-24 ms8000001184766686 来自河北省

可以用内脏感觉神经的机制，把信号放大，用来检测和预防肿瘤

22 0
[GetPortalCommentsPageByObjectIdResponse(id=2164510, encodeId=77e5216451065, content=我觉得治疗胃癌的关键可能在脾脏, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:46:46 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164509, encodeId=20762164509af, content=要是不发生肿瘤为什么, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:45:22 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164508, encodeId=bf33216450827, content=心脏和小肠能发生肿瘤吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:44:52 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164506, encodeId=2f8f2164506d9, content=可以用内脏感觉神经的机制，把信号放大，用来检测和预防肿瘤, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:23:45 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164505, encodeId=6ada216450527, content=内脏感觉神经是机制, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:20:52 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164504, encodeId=76b1216450490, content=变化的物质超级追踪吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:20:02 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164503, encodeId=a954216450347, content=肿瘤细胞在发生过程中代谢会变化吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:19:10 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164502, encodeId=08cb2164502c2, content=心肌用什么代谢物，可以标记吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:18:21 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164512, encodeId=3f6d216451294, content=我觉得肺癌和大肠癌症，可能是一类，疾病, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:49:59 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省)]
2023-10-24 ms8000001184766686 来自河北省

内脏感觉神经是机制

22 0
[GetPortalCommentsPageByObjectIdResponse(id=2164510, encodeId=77e5216451065, content=我觉得治疗胃癌的关键可能在脾脏, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:46:46 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164509, encodeId=20762164509af, content=要是不发生肿瘤为什么, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:45:22 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164508, encodeId=bf33216450827, content=心脏和小肠能发生肿瘤吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:44:52 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164506, encodeId=2f8f2164506d9, content=可以用内脏感觉神经的机制，把信号放大，用来检测和预防肿瘤, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:23:45 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164505, encodeId=6ada216450527, content=内脏感觉神经是机制, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:20:52 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164504, encodeId=76b1216450490, content=变化的物质超级追踪吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:20:02 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164503, encodeId=a954216450347, content=肿瘤细胞在发生过程中代谢会变化吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:19:10 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164502, encodeId=08cb2164502c2, content=心肌用什么代谢物，可以标记吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:18:21 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164512, encodeId=3f6d216451294, content=我觉得肺癌和大肠癌症，可能是一类，疾病, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:49:59 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省)]
2023-10-24 ms8000001184766686 来自河北省

变化的物质超级追踪吗

20 0
[GetPortalCommentsPageByObjectIdResponse(id=2164510, encodeId=77e5216451065, content=我觉得治疗胃癌的关键可能在脾脏, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:46:46 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164509, encodeId=20762164509af, content=要是不发生肿瘤为什么, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:45:22 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164508, encodeId=bf33216450827, content=心脏和小肠能发生肿瘤吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:44:52 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164506, encodeId=2f8f2164506d9, content=可以用内脏感觉神经的机制，把信号放大，用来检测和预防肿瘤, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:23:45 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164505, encodeId=6ada216450527, content=内脏感觉神经是机制, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:20:52 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164504, encodeId=76b1216450490, content=变化的物质超级追踪吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:20:02 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164503, encodeId=a954216450347, content=肿瘤细胞在发生过程中代谢会变化吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:19:10 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164502, encodeId=08cb2164502c2, content=心肌用什么代谢物，可以标记吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:18:21 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164512, encodeId=3f6d216451294, content=我觉得肺癌和大肠癌症，可能是一类，疾病, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:49:59 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省)]
2023-10-24 ms8000001184766686 来自河北省

肿瘤细胞在发生过程中代谢会变化吗

23 0
[GetPortalCommentsPageByObjectIdResponse(id=2164510, encodeId=77e5216451065, content=我觉得治疗胃癌的关键可能在脾脏, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:46:46 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164509, encodeId=20762164509af, content=要是不发生肿瘤为什么, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:45:22 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164508, encodeId=bf33216450827, content=心脏和小肠能发生肿瘤吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:44:52 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164506, encodeId=2f8f2164506d9, content=可以用内脏感觉神经的机制，把信号放大，用来检测和预防肿瘤, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:23:45 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164505, encodeId=6ada216450527, content=内脏感觉神经是机制, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:20:52 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164504, encodeId=76b1216450490, content=变化的物质超级追踪吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:20:02 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164503, encodeId=a954216450347, content=肿瘤细胞在发生过程中代谢会变化吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:19:10 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164502, encodeId=08cb2164502c2, content=心肌用什么代谢物，可以标记吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:18:21 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164512, encodeId=3f6d216451294, content=我觉得肺癌和大肠癌症，可能是一类，疾病, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:49:59 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省)]
2023-10-24 ms8000001184766686 来自河北省

心肌用什么代谢物，可以标记吗

23 0
[GetPortalCommentsPageByObjectIdResponse(id=2164510, encodeId=77e5216451065, content=我觉得治疗胃癌的关键可能在脾脏, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:46:46 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164509, encodeId=20762164509af, content=要是不发生肿瘤为什么, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:45:22 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164508, encodeId=bf33216450827, content=心脏和小肠能发生肿瘤吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:44:52 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164506, encodeId=2f8f2164506d9, content=可以用内脏感觉神经的机制，把信号放大，用来检测和预防肿瘤, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:23:45 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164505, encodeId=6ada216450527, content=内脏感觉神经是机制, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:20:52 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164504, encodeId=76b1216450490, content=变化的物质超级追踪吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:20:02 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164503, encodeId=a954216450347, content=肿瘤细胞在发生过程中代谢会变化吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:19:10 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164502, encodeId=08cb2164502c2, content=心肌用什么代谢物，可以标记吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:18:21 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省), GetPortalCommentsPageByObjectIdResponse(id=2164512, encodeId=3f6d216451294, content=我觉得肺癌和大肠癌症，可能是一类，疾病, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a5018583938, createdName=ms8000001184766686, createdTime=Tue Oct 24 02:49:59 CST 2023, time=2023-10-24, status=1, ipAttribution=河北省)]
2023-10-24 ms8000001184766686 来自河北省

我觉得肺癌和大肠癌症，可能是一类，疾病

19 0

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