JACC:贲门上部脂肪组织或与冠脉事件相关

2013-02-27 高晓方 译 医学论坛网

    德国学者的一项研究表明,在普通人群中,贲门上部脂肪组织(EAT)与致命性和非致命性冠脉事件具有相关性,并且独立于传统心血管危险因素。论文于2013年2月在线发表于《美国心血管病学会杂志》(J Am Coll Cardiol)。   此项研究的无心血管疾病受试者来自于基于人群的前瞻性Heinz Nixdorf Recall队列研

贲门上部脂肪组织
 

  德国学者的一项研究表明,在普通人群中,贲门上部脂肪组织(EAT)与致命性和非致命性冠脉事件具有相关性,并且独立于传统心血管危险因素。论文于2013年2月在线发表于《美国心血管病学会杂志》(J Am Coll Cardiol)。

  此项研究的无心血管疾病受试者来自于基于人群的前瞻性Heinz Nixdorf Recall队列研究。在随访8.0 ± 1.5年期间对偶发性冠脉事件进行评估。利用回归分析评估EAT与心血管危险因素、冠状动脉钙化(CAC)和冠脉事件的多变量相关性。

  结果显示,在4093例受试者(年龄59.4岁,男性47%)中,共有130例出现致命和非致命性冠脉事件。冠脉事件发病率随EAT四分位数升高而增加;第1和第4四分位分别为0.9%和4.7%(P<0.001)。对心血管危险因素进行校正之后,EAT倍增与冠脉事件风险升高1.5倍具有相关性(危险比[HR] 1.54),并且对CAC评分行进一步校正后相关性仍存在。对伴和未伴冠脉事件受试者进行区分之后,EAT的Harrell's一致性指数和可解释变差较传统心血管危险因素有改善趋势,但不具有统计学显著性。

冠脉相关的拓展阅读:


Objectives  
This study sought to determine whether epicardial fat volume predicts coronary events in the general population.
Background  
Epicardial adipose tissue (EAT) is suggested to promote plaque development in the coronary artery tree.
Methods  
We quantified EAT volume in participants from the prospective population-based Heinz Nixdorf Recall cohort study free of cardiovascular disease. Incident coronary events were assessed during a follow-up period of 8.0 ± 1.5 years. Multivariable association of EAT with cardiovascular risk factors, coronary artery calcification (CAC), and coronary events was assessed using regression analysis.
Results  
From the overall 4,093 participants (age 59.4 years, 47% male), 130 subjects developed a fatal or nonfatal coronary event. Incidence of coronary events increased by quartile of EAT (0.9% vs. 4.7% for 1st and 4th quartile, respectively, p < 0.001). Doubling of EAT was associated with a 1.5-fold risk of coronary events when adjusting for cardiovascular risk factors (hazard ratio [HR] [95% confidence interval (CI)]: 1.54 [1.09 to 2.19]), which remained unaltered after further adjustment for CAC score (HR [95% CI]: 1.50 [1.07 to 2.11]). For discrimination of subjects with events from those without, we observed a trend for improvement of Harrell's C and explained variance by EAT over traditional cardiovascular risk factors, which, however, did not reach statistical significance (0.720 to 0.730 for risk factors alone and with EAT added, respectively, p = 0.10, R2 = 2.73% to R2 = 2.92%, time-dependent integrated discrimination improvement = 0.196%).
Conclusions  
Epicardial fat is associated with fatal and nonfatal coronary events in the general population independent of traditional cardiovascular risk factors and complements information from cardiac computed tomography above the CAC score.

    

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1747122, encodeId=bb8b1e471225c, content=<a href='/topic/show?id=d9d192468dd' target=_blank style='color:#2F92EE;'>#贲门#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92468, encryptionId=d9d192468dd, topicName=贲门)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d50035925343, createdName=gostraight, createdTime=Thu Apr 04 06:45:00 CST 2013, time=2013-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009983, encodeId=dec8200998320, content=<a href='/topic/show?id=6e869246941' target=_blank style='color:#2F92EE;'>#贲门上部脂肪组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92469, encryptionId=6e869246941, topicName=贲门上部脂肪组织)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7387164, createdName=zhangj7108, createdTime=Mon Sep 16 07:45:00 CST 2013, time=2013-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1634815, encodeId=4a551634815ad, content=<a href='/topic/show?id=dbcc30940cb' target=_blank style='color:#2F92EE;'>#冠脉事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30940, encryptionId=dbcc30940cb, topicName=冠脉事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccfc22296342, createdName=ms3117646317107274, createdTime=Sun Jan 26 07:45:00 CST 2014, time=2014-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1853217, encodeId=4bfd185321eed, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sun May 19 08:45:00 CST 2013, time=2013-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1324803, encodeId=9ee3132480376, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Mar 01 06:45:00 CST 2013, time=2013-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345719, encodeId=99a61345e19ff, content=<a href='/topic/show?id=f8c5843e3c5' target=_blank style='color:#2F92EE;'>#脂肪组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84373, encryptionId=f8c5843e3c5, topicName=脂肪组织)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=66962500501, createdName=yige2004, createdTime=Fri Mar 01 06:45:00 CST 2013, time=2013-03-01, status=1, ipAttribution=)]
    2013-04-04 gostraight
  2. [GetPortalCommentsPageByObjectIdResponse(id=1747122, encodeId=bb8b1e471225c, content=<a href='/topic/show?id=d9d192468dd' target=_blank style='color:#2F92EE;'>#贲门#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92468, encryptionId=d9d192468dd, topicName=贲门)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d50035925343, createdName=gostraight, createdTime=Thu Apr 04 06:45:00 CST 2013, time=2013-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009983, encodeId=dec8200998320, content=<a href='/topic/show?id=6e869246941' target=_blank style='color:#2F92EE;'>#贲门上部脂肪组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92469, encryptionId=6e869246941, topicName=贲门上部脂肪组织)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7387164, createdName=zhangj7108, createdTime=Mon Sep 16 07:45:00 CST 2013, time=2013-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1634815, encodeId=4a551634815ad, content=<a href='/topic/show?id=dbcc30940cb' target=_blank style='color:#2F92EE;'>#冠脉事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30940, encryptionId=dbcc30940cb, topicName=冠脉事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccfc22296342, createdName=ms3117646317107274, createdTime=Sun Jan 26 07:45:00 CST 2014, time=2014-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1853217, encodeId=4bfd185321eed, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sun May 19 08:45:00 CST 2013, time=2013-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1324803, encodeId=9ee3132480376, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Mar 01 06:45:00 CST 2013, time=2013-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345719, encodeId=99a61345e19ff, content=<a href='/topic/show?id=f8c5843e3c5' target=_blank style='color:#2F92EE;'>#脂肪组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84373, encryptionId=f8c5843e3c5, topicName=脂肪组织)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=66962500501, createdName=yige2004, createdTime=Fri Mar 01 06:45:00 CST 2013, time=2013-03-01, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1747122, encodeId=bb8b1e471225c, content=<a href='/topic/show?id=d9d192468dd' target=_blank style='color:#2F92EE;'>#贲门#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92468, encryptionId=d9d192468dd, topicName=贲门)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d50035925343, createdName=gostraight, createdTime=Thu Apr 04 06:45:00 CST 2013, time=2013-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009983, encodeId=dec8200998320, content=<a href='/topic/show?id=6e869246941' target=_blank style='color:#2F92EE;'>#贲门上部脂肪组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92469, encryptionId=6e869246941, topicName=贲门上部脂肪组织)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7387164, createdName=zhangj7108, createdTime=Mon Sep 16 07:45:00 CST 2013, time=2013-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1634815, encodeId=4a551634815ad, content=<a href='/topic/show?id=dbcc30940cb' target=_blank style='color:#2F92EE;'>#冠脉事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30940, encryptionId=dbcc30940cb, topicName=冠脉事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccfc22296342, createdName=ms3117646317107274, createdTime=Sun Jan 26 07:45:00 CST 2014, time=2014-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1853217, encodeId=4bfd185321eed, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sun May 19 08:45:00 CST 2013, time=2013-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1324803, encodeId=9ee3132480376, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Mar 01 06:45:00 CST 2013, time=2013-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345719, encodeId=99a61345e19ff, content=<a href='/topic/show?id=f8c5843e3c5' target=_blank style='color:#2F92EE;'>#脂肪组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84373, encryptionId=f8c5843e3c5, topicName=脂肪组织)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=66962500501, createdName=yige2004, createdTime=Fri Mar 01 06:45:00 CST 2013, time=2013-03-01, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1747122, encodeId=bb8b1e471225c, content=<a href='/topic/show?id=d9d192468dd' target=_blank style='color:#2F92EE;'>#贲门#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92468, encryptionId=d9d192468dd, topicName=贲门)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d50035925343, createdName=gostraight, createdTime=Thu Apr 04 06:45:00 CST 2013, time=2013-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009983, encodeId=dec8200998320, content=<a href='/topic/show?id=6e869246941' target=_blank style='color:#2F92EE;'>#贲门上部脂肪组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92469, encryptionId=6e869246941, topicName=贲门上部脂肪组织)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7387164, createdName=zhangj7108, createdTime=Mon Sep 16 07:45:00 CST 2013, time=2013-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1634815, encodeId=4a551634815ad, content=<a href='/topic/show?id=dbcc30940cb' target=_blank style='color:#2F92EE;'>#冠脉事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30940, encryptionId=dbcc30940cb, topicName=冠脉事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccfc22296342, createdName=ms3117646317107274, createdTime=Sun Jan 26 07:45:00 CST 2014, time=2014-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1853217, encodeId=4bfd185321eed, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sun May 19 08:45:00 CST 2013, time=2013-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1324803, encodeId=9ee3132480376, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Mar 01 06:45:00 CST 2013, time=2013-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345719, encodeId=99a61345e19ff, content=<a href='/topic/show?id=f8c5843e3c5' target=_blank style='color:#2F92EE;'>#脂肪组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84373, encryptionId=f8c5843e3c5, topicName=脂肪组织)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=66962500501, createdName=yige2004, createdTime=Fri Mar 01 06:45:00 CST 2013, time=2013-03-01, status=1, ipAttribution=)]
    2013-05-19 hbwxf
  5. [GetPortalCommentsPageByObjectIdResponse(id=1747122, encodeId=bb8b1e471225c, content=<a href='/topic/show?id=d9d192468dd' target=_blank style='color:#2F92EE;'>#贲门#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92468, encryptionId=d9d192468dd, topicName=贲门)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d50035925343, createdName=gostraight, createdTime=Thu Apr 04 06:45:00 CST 2013, time=2013-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009983, encodeId=dec8200998320, content=<a href='/topic/show?id=6e869246941' target=_blank style='color:#2F92EE;'>#贲门上部脂肪组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92469, encryptionId=6e869246941, topicName=贲门上部脂肪组织)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7387164, createdName=zhangj7108, createdTime=Mon Sep 16 07:45:00 CST 2013, time=2013-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1634815, encodeId=4a551634815ad, content=<a href='/topic/show?id=dbcc30940cb' target=_blank style='color:#2F92EE;'>#冠脉事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30940, encryptionId=dbcc30940cb, topicName=冠脉事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccfc22296342, createdName=ms3117646317107274, createdTime=Sun Jan 26 07:45:00 CST 2014, time=2014-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1853217, encodeId=4bfd185321eed, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sun May 19 08:45:00 CST 2013, time=2013-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1324803, encodeId=9ee3132480376, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Mar 01 06:45:00 CST 2013, time=2013-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345719, encodeId=99a61345e19ff, content=<a href='/topic/show?id=f8c5843e3c5' target=_blank style='color:#2F92EE;'>#脂肪组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84373, encryptionId=f8c5843e3c5, topicName=脂肪组织)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=66962500501, createdName=yige2004, createdTime=Fri Mar 01 06:45:00 CST 2013, time=2013-03-01, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1747122, encodeId=bb8b1e471225c, content=<a href='/topic/show?id=d9d192468dd' target=_blank style='color:#2F92EE;'>#贲门#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92468, encryptionId=d9d192468dd, topicName=贲门)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d50035925343, createdName=gostraight, createdTime=Thu Apr 04 06:45:00 CST 2013, time=2013-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009983, encodeId=dec8200998320, content=<a href='/topic/show?id=6e869246941' target=_blank style='color:#2F92EE;'>#贲门上部脂肪组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92469, encryptionId=6e869246941, topicName=贲门上部脂肪组织)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7387164, createdName=zhangj7108, createdTime=Mon Sep 16 07:45:00 CST 2013, time=2013-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1634815, encodeId=4a551634815ad, content=<a href='/topic/show?id=dbcc30940cb' target=_blank style='color:#2F92EE;'>#冠脉事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30940, encryptionId=dbcc30940cb, topicName=冠脉事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccfc22296342, createdName=ms3117646317107274, createdTime=Sun Jan 26 07:45:00 CST 2014, time=2014-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1853217, encodeId=4bfd185321eed, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sun May 19 08:45:00 CST 2013, time=2013-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1324803, encodeId=9ee3132480376, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Mar 01 06:45:00 CST 2013, time=2013-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345719, encodeId=99a61345e19ff, content=<a href='/topic/show?id=f8c5843e3c5' target=_blank style='color:#2F92EE;'>#脂肪组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84373, encryptionId=f8c5843e3c5, topicName=脂肪组织)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=66962500501, createdName=yige2004, createdTime=Fri Mar 01 06:45:00 CST 2013, time=2013-03-01, status=1, ipAttribution=)]