Lancet Diab & Endo:中国人更容易患糖尿病?

2014-10-11 伊文 柳叶刀

全球每4位糖尿病患者中就有1位来自中国。看来,中国人似乎比其他国家的人更容易患上糖尿病。但为什么?发表在《柳叶刀》上的系列文章认为,糖尿病的蔓延,是生物进化与当今外界环境间不协调的结果。 从大环境来看,中国经济飞速发展,城市化进程加快,人们的生活方式与饮食习惯出现显著变化。比如含糖饮料、膳食脂肪、红肉以及细粮充斥每日餐桌,而这些以及米饭的摄入数量与质量,也在一定程度上也影响着2型糖尿病的

全球每4位糖尿病患者中就有1位来自中国。看来,中国人似乎比其他国家的人更容易患上糖尿病。但为什么?发表在《柳叶刀》上的系列文章认为,糖尿病的蔓延,是生物进化与当今外界环境间不协调的结果。

从大环境来看,中国经济飞速发展,城市化进程加快,人们的生活方式与饮食习惯出现显著变化。比如含糖饮料、膳食脂肪、红肉以及细粮充斥每日餐桌,而这些以及米饭的摄入数量与质量,也在一定程度上也影响着2型糖尿病的发生风险。

另外,缺乏运动也是中国人群的生活常态。有研究显示,2010年仅有11.9%的中国成年人进行日常锻炼。在1991年~1997年购买汽车的中国男士比没有购车的多增加了1.8公斤的体重。

此外,遗传背景也是很重要的因素。学者们指出,家族因素如遗传变异非常重要,遗传结构的差异表明,与欧裔人群相比,不同遗传变异组合可能是中国人群中2型糖尿病最重要的风险因素。

因此,对于高度遗传易感性的个体,肥胖、不良生活方式和环境因素等的影响尤为容易扣动发病的“扳机”。要知道,糖尿病的发生从出生前到终老,都存在风险(图)。

  

比如在生命早期,母体营养不良、母体肥胖和妊娠期糖尿病等就均与后代糖尿病发病风险增高相关。

因此,学者们认为,目前亟需针对生命周期不同阶段的风险因素采取多种防御措施,以降低糖尿病的发生、发展。

原始出处:

Ma RC1, Lin X2, Jia W3.Causes of type 2 diabetes in China.Lancet Diabetes Endocrinol. 2014 Sep 10. pii: S2213-8587(14)70145-7. doi: 10.1016/S2213-8587(14)70145-7. [Epub ahead of print]

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    2014-10-20 howi
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    2015-04-11 x35042875

    控制好糖尿病可能提高肝硬化患者的预后。

    0

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    2014-10-15 tianjin2001

    学习了,谢谢!

    0

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