JACC:梗死后室间隔缺损的体内形态学及闭合的影响

2017-06-27 xiangting MedSci原创

这是首个在活体患者中关于PIVSD的详细解剖描述。收缩期或舒张期缺损可能会更大,这意味着单相测量是不合适的。

这项研究的目的是定义梗死后室间隔缺损(PIVSD)的动态体内形态,而之前这在活体中从来没有被描述过。

PIVSD是急性心肌梗死的破坏性并发症。研究人员回顾性分析CT扫描或MRI显示的PIVSD的解剖特征。

共评估了32个PIVSDs,16个左冠状动脉和16个右冠状动脉PIVSDs。PIVSDs是大的(平均最大尺寸26.5±11.5mm,平均面积5.2±4.2cm2)和椭圆形(平均偏心指数1.7±0.5),具有薄边缘(舒张平均厚度5mm距离PIVSD的边缘6.4mm±3.0mm ),只有22%的PIVSDs完全限于隔膜。在舒张期或收缩期缺损可能更大。最大的Amplatzer封堵器干(St.Jude Medical,St.Paul,Minnesota)仅填充了50%的缺损。小缺损的患者可以在没有闭合的情况下生存。大缺损的患者没有关闭会死亡。如果闭合,PIVSD大小和冠状动脉区域不能预测>1年的生存率(总体60%)。

这是首个在活体患者中关于PIVSD的详细解剖描述。收缩期或舒张期缺损可能会更大,这意味着单相测量是不合适的。其复杂的性质意味着最常用的封堵器装置通常是不合适的。成功的关闭导致生存期延长,并应尽可能的尝试。这项研究可能会影响患者选择、改善闭合技术和装置的设计。

原始出处:
Mark C.K. Hamilton,et al. The In Vivo Morphology of Post-Infarct Ventricular Septal Defect and the Implications for Closure.JACC   Cardiovascular Interventions. June 2017.

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    2017-08-28 hbwxf
  3. [GetPortalCommentsPageByObjectIdResponse(id=1924273, encodeId=818119242e35d, content=<a href='/topic/show?id=a1444624457' target=_blank style='color:#2F92EE;'>#室间隔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46244, encryptionId=a1444624457, topicName=室间隔)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05202500204, createdName=minhuang75_72521584, createdTime=Sat Mar 24 23:41:00 CST 2018, time=2018-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1853669, encodeId=a8aa185366914, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Mon Aug 28 15:41:00 CST 2017, time=2017-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216767, encodeId=e794216e6765, content=不错的,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Thu Jun 29 18:54:28 CST 2017, time=2017-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325410, encodeId=a48013254108c, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Thu Jun 29 06:41:00 CST 2017, time=2017-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216051, encodeId=9e4e2160517d, content=签到学习了很多。, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A3E53E62691178E2F18D7B999FD22131/100, createdBy=f44d2003846, createdName=Chongyang Zhang, createdTime=Tue Jun 27 17:29:45 CST 2017, time=2017-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216028, encodeId=d18c21602857, content=这是首个在活体患者中关于PIVSD的详细解剖描述。收缩期或舒张期缺损可能会更大,这意味着单相测量是不合适的。其复杂的性质意味着最常用的封堵器装置通常是不合适的。成功的关闭导致生存期延长,并应尽可能的尝试。这项研究可能会影响患者选择、改善闭合技术和装置的设计。, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Tue Jun 27 16:58:27 CST 2017, time=2017-06-27, status=1, ipAttribution=)]
    2017-06-29 虈亣靌

    不错的,学习了,谢谢分享!

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1924273, encodeId=818119242e35d, content=<a href='/topic/show?id=a1444624457' target=_blank style='color:#2F92EE;'>#室间隔#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46244, encryptionId=a1444624457, topicName=室间隔)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05202500204, createdName=minhuang75_72521584, createdTime=Sat Mar 24 23:41:00 CST 2018, time=2018-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1853669, encodeId=a8aa185366914, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Mon Aug 28 15:41:00 CST 2017, time=2017-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216767, encodeId=e794216e6765, content=不错的,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Thu Jun 29 18:54:28 CST 2017, time=2017-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325410, encodeId=a48013254108c, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Thu Jun 29 06:41:00 CST 2017, time=2017-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216051, encodeId=9e4e2160517d, content=签到学习了很多。, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A3E53E62691178E2F18D7B999FD22131/100, createdBy=f44d2003846, createdName=Chongyang Zhang, createdTime=Tue Jun 27 17:29:45 CST 2017, time=2017-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216028, encodeId=d18c21602857, content=这是首个在活体患者中关于PIVSD的详细解剖描述。收缩期或舒张期缺损可能会更大,这意味着单相测量是不合适的。其复杂的性质意味着最常用的封堵器装置通常是不合适的。成功的关闭导致生存期延长,并应尽可能的尝试。这项研究可能会影响患者选择、改善闭合技术和装置的设计。, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Tue Jun 27 16:58:27 CST 2017, time=2017-06-27, status=1, ipAttribution=)]
    2017-06-27 Chongyang Zhang

    签到学习了很多。

    0

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    2017-06-27 有备才能无患

    这是首个在活体患者中关于PIVSD的详细解剖描述。收缩期或舒张期缺损可能会更大,这意味着单相测量是不合适的。其复杂的性质意味着最常用的封堵器装置通常是不合适的。成功的关闭导致生存期延长,并应尽可能的尝试。这项研究可能会影响患者选择、改善闭合技术和装置的设计。

    0

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