J Int Oral Health:绝经后女性的骨质疏松状况可增加牙周病的发病率及其严重程度

2015-10-12 sunshine 译 MedSci原创

J Int Oral Health:绝经后女性的骨质疏松状况可增加牙周病的发病率及其严重程度骨质疏松症及牙周炎都是局部和全身因素介导的慢性炎症反应,其特点是骨的丧失,二者具有相同的危险因素。既往研究表明,骨质疏松症本身就是绝经妇女牙周组织破坏的一个诱发因素,但是,研究表明二者仅有中等程度的联系。本研究中,我们对比了绝经后骨质疏松妇女与绝经后但并无骨质疏松的妇女的牙周病的严重程度。研究共纳入了100

骨质疏松症及牙周炎都是局部和全身因素介导的慢性炎症反应,其特点是骨的丧失,二者具有相同的危险因素。既往研究表明,骨质疏松症本身就是绝经妇女牙周组织破坏的一个诱发因素,但是,研究表明二者仅有中等程度的联系。本研究中,我们对比了绝经后骨质疏松妇女与绝经后但并无骨质疏松的妇女的牙周病的严重程度。

研究共纳入了100名绝经后妇女,年龄在50-65岁之间。随机分组:A组,50名骨质疏松症患者;B组,50名非骨质疏松症患者。测量所有研究对象的牙周参数,包括探针出血指数,简化口腔卫生指数,牙周袋深度(PPD),临床附着丧失(CAL),邻面牙槽骨丧失(ABL)以及缺牙数。双能X线骨密度仪用以评估研究对象的牙周疾病状态与全身骨密度(BMD)之间的关系。

结果表明,与B组相比,A组女性的PPD、CAL及ABL数值更大一些(P < 0.0001)。两组BMD与牙周各参数之间并无显著相关关系。

总之,本研究结果发现绝经后骨质疏松症可增加机体牙周病的发病率,并可加重机体牙周病的严重程度。应教育绝经后骨质疏松的女性认识到良好的口腔卫生护理是自我健康管理的重要部分。因而,我们可以推断出牙周手术与牙周病之间的或可存在某种联系,但是仍需要长期的前瞻性研究以提供明确的证据。

原始出处:

Juluri R, Prashanth E et al.Association of Postmenopausal Osteoporosis and Periodontal Disease: A Double-Blind Case-Control Study. J Int Oral Health. 2015 Sep;7(9):119-23.

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    2016-09-13 1e10c84am36(暂无匿称)

    好文章,还会关注

    0

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    2016-01-02 shizhenshan
  3. 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  4. 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createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Tue Feb 23 22:48:00 CST 2016, time=2016-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1257028, encodeId=ca1f125e02883, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Wed Oct 14 10:48:00 CST 2015, time=2015-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1282232, encodeId=817a128223261, content=<a href='/topic/show?id=46a06e5220c' target=_blank style='color:#2F92EE;'>#牙周病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67522, encryptionId=46a06e5220c, topicName=牙周病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1376173, createdName=linagood, createdTime=Wed Oct 14 10:48:00 CST 2015, time=2015-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450429, encodeId=a97e1450429d1, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Wed Oct 14 10:48:00 CST 2015, time=2015-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1526612, encodeId=576a1526612a8, content=<a href='/topic/show?id=2fe6e88863a' target=_blank style='color:#2F92EE;'>#绝经后女性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78886, encryptionId=2fe6e88863a, topicName=绝经后女性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b55511745984, createdName=chenhongpeng, createdTime=Wed Oct 14 10:48:00 CST 2015, time=2015-10-14, status=1, ipAttribution=)]
    2015-12-22 xiaotaiyang1

    又是系统性疾病

    0

  5. 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createdName=shizhenshan, createdTime=Sat Jan 02 08:48:00 CST 2016, time=2016-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823248, encodeId=b673182324831, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Thu Jun 30 23:48:00 CST 2016, time=2016-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47085, encodeId=66fa4e085ec, content=又是系统性疾病, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, 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createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Tue Feb 23 22:48:00 CST 2016, time=2016-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1257028, encodeId=ca1f125e02883, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Wed Oct 14 10:48:00 CST 2015, time=2015-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1282232, encodeId=817a128223261, content=<a href='/topic/show?id=46a06e5220c' target=_blank style='color:#2F92EE;'>#牙周病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67522, encryptionId=46a06e5220c, topicName=牙周病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1376173, createdName=linagood, createdTime=Wed Oct 14 10:48:00 CST 2015, time=2015-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450429, encodeId=a97e1450429d1, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Wed Oct 14 10:48:00 CST 2015, time=2015-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1526612, encodeId=576a1526612a8, content=<a href='/topic/show?id=2fe6e88863a' target=_blank style='color:#2F92EE;'>#绝经后女性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78886, encryptionId=2fe6e88863a, topicName=绝经后女性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b55511745984, createdName=chenhongpeng, createdTime=Wed Oct 14 10:48:00 CST 2015, time=2015-10-14, status=1, ipAttribution=)]
    2015-12-10 De_dzw

    休息口腔卫生

    0

  6. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67522, encryptionId=46a06e5220c, topicName=牙周病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1376173, createdName=linagood, createdTime=Wed Oct 14 10:48:00 CST 2015, time=2015-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450429, encodeId=a97e1450429d1, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Wed Oct 14 10:48:00 CST 2015, time=2015-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1526612, encodeId=576a1526612a8, content=<a href='/topic/show?id=2fe6e88863a' target=_blank style='color:#2F92EE;'>#绝经后女性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78886, encryptionId=2fe6e88863a, topicName=绝经后女性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b55511745984, createdName=chenhongpeng, createdTime=Wed Oct 14 10:48:00 CST 2015, time=2015-10-14, status=1, ipAttribution=)]
    2016-02-23 小几洁
  7. 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重要性: 百分之八十五的被收容的老年人相对于社区老年人,骨质疏松症骨折率的程度要高8到9倍。然而,大多数的人不及时治疗骨质疏松,被排除在关键的试验之外。 摘要目的: 确定唑来膦酸针对于虚弱的长期护理的老年妇女用于治疗骨质疏松症的疗效和安全性。 设计,设定和参与者: 从2007年12月到2012年3月间,我们进行了2年,随机,安慰剂对照的,双盲研究。包括181名妇女,65岁或以上的老年骨质疏松症

Pediatr Obes:补充维生素D剂量越大越好?不一定

梅奥诊所的通过对肥胖儿童进行调查,将调查结果发表在Pediatric Obesity杂志上。根据CDC的调查显示,肥胖儿童的数量是30年前的2倍,肥胖的青少年是三十年前的4倍。JAMA报道,1/5的美国青少年处于肥胖状态。许多观察性研究表明,维生素D缺乏会导致青少年出现肥胖相关性并发症,如患心血管疾病和胰岛素抵抗。因此。许多医疗机构建议青少年摄入高剂量的维生素D,以减缓并发症的发展或避免疾病的出现

J Cell Biochem:警惕老年人补钙的心血管并发症

长期以来人们众所周知:补充钙剂有可能增加肾功能不全病人发生心血管疾病的风险。最近“奥克兰钙实验”的研究学学者表明,这些心血管事件风险也可能发生在希望通过使用钙剂达到预防骨质疏松症目的的老年人身上。研究者后续的Meta-分析亦证实,老人补充钙剂,无论与此同时补充或者不补充维生素D,都对于心血管系统有着一定程度不利的影响——增加心肌梗死和脑卒中的发生风险。 Kaplan–Meier生存曲线(心梗及中风