Aust Dent J:Er:YAG激光治疗慢性牙周炎后牙周致病菌的水平

2015-03-29 MedSci MedSci原创

Aust Dent J:Er:YAG激光治疗慢性牙周炎后牙周致病菌的水平关键词:Er:YAG激光 慢性牙周炎 牙周致病菌 qRT-PCR  SRP慢性牙周炎是细菌诱导的炎症性疾病,临床表现为结缔组织附着丧失,牙槽骨吸收,牙周袋形成。世界上,牙周炎是成人失牙的首要原因。牙周袋内定植的微生物是以菌斑微生物膜的形式存在的,多种细菌的复杂作用引发了宿主的免疫反应,二者最终导致了牙周炎的发生发展


慢性牙周炎是细菌诱导的炎症性疾病,临床表现为结缔组织附着丧失,牙槽骨吸收,牙周袋形成。世界上,牙周炎是成人失牙的首要原因。牙周袋内定植的微生物是以菌斑微生物膜的形式存在的,多种细菌的复杂作用引发了宿主的免疫反应,二者最终导致了牙周炎的发生发展。
当前牙周炎的治疗主要是机械性去除龈上和龈下菌斑。洁治和跟面平整(SRP)通常具有局限性,不能清除不能到达的深牙周袋内的致病菌。而Er:YAG激光可以清除根面的致病菌,可快速而有效的防止细菌的定植,并可显著改善临床附着水平。

目的:比较Er:YAG激光和SRP治疗慢性牙周炎后牙周致病菌的水平。

方法:口内分组,随机分为两个象限。收集21位患者的250例龈下菌斑,分别为治疗前、治疗后第六周和治疗后第十二周的菌斑。使用多重qPCR测定牙龈卟啉单胞菌(Pg)、齿垢密螺旋体(Td)、褔赛坦氏菌(Tf)和伴放线放线杆菌(Aa)的水平。

结果:经ERL或SRP治疗后Tf和Pg的水平明显降低。ERL治疗后第十二周Td明显降低,SRP治疗后第十二周Aa明显降低。对比治疗后第六周和第十二周的结果,差异无统计学意义。

结论:与治疗金标准SRP相比,Er:YAG同样可显著减少Tf和Pg的水平,但是在清除Td上ERL较SRP有效,在清除Aa上SRP较ERL更为有效。

原始出处:

Milne TJ, Coates DE, Leichter JW, Soo L, Williams SM, Seymour GJ, Cullinan MP. Periodontopathogen levels following the use of an Er:YAG laser in the treatment of
chronic periodontitis.
Aust Dent J.2015 Jan 29. doi: 10.1111/adj.12306. 

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    2016-09-13 1e10c84am36(暂无匿称)

    好文章,还会关注

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    2015-07-07 hyf028
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    2015-03-30 ixiaochengdudu

    Aa就是个难搞的货

    0

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    2015-03-30 oliver169
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  7. [GetPortalCommentsPageByObjectIdResponse(id=125373, encodeId=32681253e362, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 14:31:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2005139, encodeId=643b2005139cb, content=<a href='/topic/show?id=2e1e6e542cb' target=_blank style='color:#2F92EE;'>#牙周致病菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67542, encryptionId=2e1e6e542cb, topicName=牙周致病菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60b4474, createdName=bbwuyu_003, createdTime=Sun Nov 29 07:27:00 CST 2015, time=2015-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2033274, encodeId=521020332e4d3, content=<a href='/topic/show?id=692328816d7' target=_blank style='color:#2F92EE;'>#光治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28816, encryptionId=692328816d7, topicName=光治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7d40148, createdName=hyf028, createdTime=Tue Jul 07 12:27:00 CST 2015, time=2015-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=19074, encodeId=c714190e4de, content=Aa就是个难搞的货, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=ixiaochengdudu, createdTime=Mon Mar 30 16:43:00 CST 2015, time=2015-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279645, encodeId=42e212e964511, content=<a href='/topic/show?id=265c66e50ea' target=_blank style='color:#2F92EE;'>#激光#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66750, encryptionId=265c66e50ea, topicName=激光)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4fd6156, createdName=oliver169, createdTime=Mon Mar 30 15:27:00 CST 2015, time=2015-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1368614, encodeId=20da1368614da, content=<a href='/topic/show?id=0e30535657b' target=_blank style='color:#2F92EE;'>#慢性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53565, encryptionId=0e30535657b, topicName=慢性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c64275, createdName=piaojinhua, createdTime=Mon Mar 30 15:27:00 CST 2015, time=2015-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1434708, encodeId=16451434e0811, content=<a href='/topic/show?id=817f66e686a' target=_blank style='color:#2F92EE;'>#激光治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66768, encryptionId=817f66e686a, topicName=激光治疗)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Mon Mar 30 15:27:00 CST 2015, time=2015-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450397, encodeId=2243145039e53, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Mon Mar 30 15:27:00 CST 2015, time=2015-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626185, encodeId=49321626185b7, content=<a href='/topic/show?id=c11d864884d' target=_blank style='color:#2F92EE;'>#致病菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86488, encryptionId=c11d864884d, topicName=致病菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32d320995014, createdName=cooco, createdTime=Mon Mar 30 15:27:00 CST 2015, time=2015-03-30, status=1, ipAttribution=)]
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    2015-03-30 cooco